Glycosyl coumarin carbonic anhydrase IX and XII inhibitors strongly attenuate the growth of primary breast tumors.
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Non-Classical Inhibition of Carbonic AnhydraseOvercoming Hypoxia-Mediated Tumor Progression: Combinatorial Approaches Targeting pH Regulation, Angiogenesis and Immune DysfunctionTargeting hypoxic response for cancer therapyAntioxidant Mechanisms and ROS-Related MicroRNAs in Cancer Stem CellsRecent developments in targeting carbonic anhydrase IX for cancer therapeuticsDithiocarbamates Strongly Inhibit Carbonic Anhydrases and Show Antiglaucoma Action in VivoCarbonic anhydrase IX inhibitors in cancer therapy: an update.Tumor microenvironmental changes induced by the sulfamate carbonic anhydrase IX inhibitor S4 in a laryngeal tumor modelMicroenvironmental acidosis in carcinogenesis and metastases: new strategies in prevention and therapy.A class of 4-sulfamoylphenyl-ω-aminoalkyl ethers with effective carbonic anhydrase inhibitory action and antiglaucoma effects.Synthesis, antitumor activity, and mechanism of action of 6-acrylic phenethyl ester-2-pyranone derivatives.Combination of lactate calcium salt with 5-indanesulfonamide and α-cyano-4-hydroxycinnamic acid to enhance the antitumor effect on HCT116 cells via intracellular acidificationStructure-based drug discovery of carbonic anhydrase inhibitors.Anti-infective carbonic anhydrase inhibitors: a patent and literature review.Exploiting the hydrophobic and hydrophilic binding sites for designing carbonic anhydrase inhibitors.Antiglaucoma carbonic anhydrase inhibitors: a patent review.Designing carbonic anhydrase inhibitors for the treatment of breast cancer.How many carbonic anhydrase inhibition mechanisms exist?Co-targeting intracellular pH and essential amino acid uptake cooperates to induce cell death of T-ALL/LL cells.Drug interaction considerations in the therapeutic use of carbonic anhydrase inhibitors.Design, Synthesis and Cytotoxicity of Novel Dihydroartemisinin-Coumarin Hybrids via Click Chemistry.Advances in structure-based drug discovery of carbonic anhydrase inhibitors.Anti-tumour activity of a novel coumarin-chalcone hybrid is mediated through intrinsic apoptotic pathway by inducing PUMA and altering Bax/Bcl-2 ratio.Targeting carbonic anhydrase IX depletes breast cancer stem cells within the hypoxic niche.Microwave-assisted extraction, HPLC analysis, and inhibitory effects on carbonic anhydrase I, II, VA, and VII isoforms of 14 blueberry Italian cultivars.Carbonic Anhydrase Glycoinhibitors belonging to the Aminoxysulfonamide Series.Carbonic Anhydrase Inhibition and the Management of Hypoxic Tumors.Targeting ion transport in cancerSynthesis of aminocyanopyrazoles via a multi-component reaction and anti-carbonic anhydrase inhibitory activity of their sulfamide derivatives against cytosolic and transmembrane isoforms.Novel antibody to a carbonic anhydrase: patent evaluation of WO2011138279A1.Novel coumarins and benzocoumarins acting as isoform-selective inhibitors against the tumor-associated carbonic anhydrase IX.7-Amino-3,4-dihydro-1H-quinolin-2-one, a compound similar to the substituted coumarins, inhibits α-carbonic anhydrases without hydrolysis of the lactam ring.Synthesis, biological activity and multiscale molecular modeling studies for coumaryl-carboxamide derivatives as selective carbonic anhydrase IX inhibitors.Sulfocoumarin-, Coumarin-, 4-Sulfamoylphenyl-Bearing Indazole-3-carboxamide Hybrids: Synthesis and Selective Inhibition of Tumor-Associated Carbonic Anhydrase Isozymes IX and XII.Novel 6- and 7-Substituted Coumarins with Inhibitory Action against Lipoxygenase and Tumor-Associated Carbonic Anhydrase IX.Rethinking the Combination of Proton Exchanger Inhibitors in Cancer Therapy.Design, synthesis and evaluation of 18F-labeled cationic carbonic anhydrase IX inhibitors for PET imaging.Probing binding specificity of the sucrose transporter AtSUC2 with fluorescent coumarin glucosides.A substituted sulfonamide and its Co (II), Cu (II), and Zn (II) complexes as potential antifungal agents.Monoclonal antibodies raised against 167-180 aa sequence of human carbonic anhydrase XII inhibit its enzymatic activity.
P2860
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P2860
Glycosyl coumarin carbonic anhydrase IX and XII inhibitors strongly attenuate the growth of primary breast tumors.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
Glycosyl coumarin carbonic anh ...... owth of primary breast tumors.
@en
Glycosyl coumarin carbonic anh ...... owth of primary breast tumors.
@nl
type
label
Glycosyl coumarin carbonic anh ...... owth of primary breast tumors.
@en
Glycosyl coumarin carbonic anh ...... owth of primary breast tumors.
@nl
prefLabel
Glycosyl coumarin carbonic anh ...... owth of primary breast tumors.
@en
Glycosyl coumarin carbonic anh ...... owth of primary breast tumors.
@nl
P2093
P50
P356
P1476
Glycosyl coumarin carbonic anh ...... rowth of primary breast tumors
@en
P2093
Alfonso Maresca
Claudiu T Supuran
Nadia Touisni
Paul C McDonald
Yuanmei Lou
P304
P356
10.1021/JM200983E
P407
P577
2011-11-22T00:00:00Z