c-Myc mediates pre-TCR-induced proliferation but not developmental progression - Wikidata - awgldk - TriplyDB

c-Myc mediates pre-TCR-induced proliferation but not developmental progression

c-Myc mediates pre-TCR-induced proliferation but not developmental progression

http://www.wikidata.org/entity/Q42742027

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ShcA regulates thymocyte proliferation through specific transcription factors and a c-Abl-dependent signaling axis.TLX1 and NOTCH coregulate transcription in T cell acute lymphoblastic leukemia cells.The transcription factor Myc controls metabolic reprogramming upon T lymphocyte activation Notch dimerization is required for leukemogenesis and T-cell development.Transcriptional control of invariant NKT cell development.A NOTCH1-driven MYC enhancer promotes T cell development, transformation and acute lymphoblastic leukemia.A critical role for Mnt in Myc-driven T-cell proliferation and oncogenesis Immature single-positive CD8+ thymocytes represent the transition from Notch-dependent to Notch-independent T-cell development.RasGRP1, but not RasGRP3, is required for efficient thymic β-selection and ERK activation downstream of CXCR4 Miz-1 regulates translation of Trp53 via ribosomal protein L22 in cells undergoing V(D)J recombination Myc roles in hematopoiesis and leukemia Differential requirements for c-Myc in chronic hematopoietic hyperplasia and acute hematopoietic malignancies in Pten-null mice.Downregulation of the transcription factor KLF4 is required for the lineage commitment of T cells.Gads regulates the expansion phase of CD8+ T cell-mediated immunity.Asymmetric cell division during T cell development controls downstream fate.HES1 opposes a PTEN-dependent check on survival, differentiation, and proliferation of TCRβ-selected mouse thymocytes.T cell receptor-instructed alphabeta versus gammadelta lineage commitment revealed by single-cell analysis.Glucose and glutamine fuel protein O-GlcNAcylation to control T cell self-renewal and malignancy.β-Selection-induced proliferation is required for αβ T cell differentiation.Notch signaling in leukemia.Harnessing endogenous miR-181a to segregate transgenic antigen receptor expression in developing versus post-thymic T cells in murine hematopoietic chimeras.Intrathymic proliferation wave essential for Valpha14+ natural killer T cell development depends on c-Myc.An overview of MYC and its interactome.β-Catenin induces T-cell transformation by promoting genomic instability.c-Myc inhibition prevents leukemia initiation in mice and impairs the growth of relapsed and induction failure pediatric T-ALL cells.MYC in Regulating Immunity: Metabolism and Beyond.Regulation of glucose metabolism in T cells: new insight into the role of Phosphoinositide 3-kinases.mTORC1 regulates CD8+ T-cell glucose metabolism and function independently of PI3K and PKB.Cellular metabolism on T-cell development and function.Transcription factors and target genes of pre-TCR signaling.Single cell tuning of Myc expression by antigen receptor signal strength and interleukin-2 in T lymphocytes.The transcriptional landscape of αβ T cell differentiation.Aberrant Signaling Pathways in T-Cell Acute Lymphoblastic Leukemia.Placing ion channels into a signaling network of T cells: from maturing thymocytes to healthy T lymphocytes or leukemic T lymphoblasts.An oncogenic enhancer enemy (N-Me) in T-ALL Oncogenes in immune cells as potential therapeutic targets.Role of Polyamines in Immune Cell Functions.The Transcription Factor Zfx Regulates Peripheral T Cell Self-Renewal and Proliferation

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c-Myc mediates pre-TCR-induced proliferation but not developmental progression

http://www.wikidata.org/entity/Q42742027

description

2006 nî lūn-bûn

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2006年の論文

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2006年論文

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2006年論文

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2006年論文

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2006年論文

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2006年論文

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2006年论文

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2006年论文

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2006年论文

@zh-cn

name

c-Myc mediates pre-TCR-induced proliferation but not developmental progression

@en

c-Myc mediates pre-TCR-induced proliferation but not developmental progression

@nl

type

label

c-Myc mediates pre-TCR-induced proliferation but not developmental progression

@en

c-Myc mediates pre-TCR-induced proliferation but not developmental progression

@nl

prefLabel

c-Myc mediates pre-TCR-induced proliferation but not developmental progression

@en

c-Myc mediates pre-TCR-induced proliferation but not developmental progression

@nl

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c-Myc mediates pre-TCR-induced proliferation but not developmental progression

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Andreas Krueger

http://www.w3.org/2001/XMLSchema#string

Damian Kovalovsky

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Fotini Gounari

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Harald von Boehmer

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Irum Khan

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Khashayarsha Khazaie

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Zhuyan Guo

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P2860

The GADD45 inhibition of Cdc2 kinase correlates with GADD45-mediated growth suppression

Three distinct IL-2 signaling pathways mediated by bcl-2, c-myc, and lck cooperate in hematopoietic cell proliferation

Genomic targets of the human c-Myc protein

An integrated database of genes responsive to the Myc oncogenic transcription factor: identification of direct genomic targets

Analysis of C-MYC function in normal cells via conditional gene-targeted mutation

Myc pathways provoking cell suicide and cancer

c-Myc binds to human ribosomal DNA and stimulates transcription of rRNA genes by RNA polymerase I

Requirement for cyclin D3 in lymphocyte development and T cell leukemias

Hedgehog signaling regulates differentiation from double-negative to double-positive thymocyte

c-Myc-deficient B lymphocytes are resistant to spontaneous and induced cell death

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