Activity profiles of 309 ToxCast™ chemicals evaluated across 292 biochemical targets.
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Current perspectives on the use of alternative species in human health and ecological hazard assessmentsThe biomechanisms of metal and metal-oxide nanoparticles' interactions with cellsComputational toxicology using the OpenTox application programming interface and BioclipseA computational model predicting disruption of blood vessel developmentHuman iPSC-derived endothelial cell sprouting assay in synthetic hydrogel arraysThe eTOX data-sharing project to advance in silico drug-induced toxicity predictionEditor's Highlight: Development of an In vitro Assay Measuring Uterine-Specific Estrogenic Responses for Use in Chemical Safety AssessmentA Workflow to Investigate Exposure and Pharmacokinetic Influences on High-Throughput in Vitro Chemical Screening Based on Adverse Outcome PathwaysIncorporating new technologies into toxicity testing and risk assessment: moving from 21st century vision to a data-driven framework.Linking field-based metabolomics and chemical analyses to prioritize contaminants of emerging concern in the Great Lakes basin.Development and Validation of a Computational Model for Androgen Receptor ActivityEnvironmental impact on vascular development predicted by high-throughput screening.Predictive in silico off-target profiling in drug discovery.The curation paradigm and application tool used for manual curation of the scientific literature at the Comparative Toxicogenomics Database.Integrated Model of Chemical Perturbations of a Biological Pathway Using 18 In Vitro High-Throughput Screening Assays for the Estrogen Receptor.Obesogens, stem cells and the developmental programming of obesity.Editor's Highlight: Negative Predictors of Carcinogenicity for Environmental Chemicals.Incorporating High-Throughput Exposure Predictions With Dosimetry-Adjusted In Vitro Bioactivity to Inform Chemical Toxicity Testing.Caenorhabditis elegans as a model in developmental toxicology.Triflumizole is an obesogen in mice that acts through peroxisome proliferator activated receptor gamma (PPARγ).Addressing Early Life Sensitivity Using Physiologically Based Pharmacokinetic Modeling and In Vitro to In Vivo Extrapolation.In vitro models for liver toxicity testing.The nematode Caenorhabditis elegans as a tool to predict chemical activity on mammalian development and identify mechanisms influencing toxicological outcomeProfiling 976 ToxCast chemicals across 331 enzymatic and receptor signaling assaysImproving the human hazard characterization of chemicals: a Tox21 updateOn the Utility of ToxCast™ and ToxPi as Methods for Identifying New Obesogens.Reply to "Comment on 'On the Utility of ToxCast™ and ToxPi as Methods for Identifying New Obesogens'".Comment on "On the Utility of ToxCast™ and ToxPi as Methods for Identifying New Obesogens".Laboratory models and their role in assessing teratogenesis.In vitro and modelling approaches to risk assessment from the U.S. Environmental Protection Agency ToxCast programme.SEURAT-1 liver gold reference compounds: a mechanism-based review.Regulatory toxicology in the twenty-first century: challenges, perspectives and possible solutions.Predicting organ toxicity using in vitro bioactivity data and chemical structure.Screening the ToxCast phase II libraries for alterations in network function using cortical neurons grown on multi-well microelectrode array (mwMEA) plates.An "EAR" on Environmental Surveillance and Monitoring: A Case Study on the Use of Exposure-Activity Ratios (EARs) to Prioritize Sites, Chemicals, and Bioactivities of Concern in Great Lakes Waters.Grouping 34 Chemicals Based on Mode of Action Using Connectivity Mapping.In Silico Prediction of Physicochemical Properties of Environmental Chemicals Using Molecular Fingerprints and Machine Learning.Relative impact of incorporating pharmacokinetics on predicting in vivo hazard and mode of action from high-throughput in vitro toxicity assays.Editor's Highlight: Analysis of the Effects of Cell Stress and Cytotoxicity on In Vitro Assay Activity Across a Diverse Chemical and Assay Space.Evaluating the Impact of Uncertainties in Clearance and Exposure When Prioritizing Chemicals Screened in High-Throughput Assays.
P2860
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P2860
Activity profiles of 309 ToxCast™ chemicals evaluated across 292 biochemical targets.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
Activity profiles of 309 ToxCast™ chemicals evaluated across 292 biochemical targets.
@en
Activity profiles of 309 ToxCast™ chemicals evaluated across 292 biochemical targets.
@nl
type
label
Activity profiles of 309 ToxCast™ chemicals evaluated across 292 biochemical targets.
@en
Activity profiles of 309 ToxCast™ chemicals evaluated across 292 biochemical targets.
@nl
prefLabel
Activity profiles of 309 ToxCast™ chemicals evaluated across 292 biochemical targets.
@en
Activity profiles of 309 ToxCast™ chemicals evaluated across 292 biochemical targets.
@nl
P2093
P50
P1433
P1476
Activity profiles of 309 ToxCast™ chemicals evaluated across 292 biochemical targets.
@en
P2093
Ann M Richard
Arthur Weissman
David J Dix
James R Rabinowitz
Keith A Houck
Nisha S Sipes
R Woodrow Setzer
Robert J Kavlock
Thomas B Knudsen
P356
10.1016/J.TOX.2010.12.010
P407
P50
P577
2011-01-18T00:00:00Z