Distinct and redundant functions of histone deacetylases HDAC1 and HDAC2 in proliferation and tumorigenesis. - Wikidata - awgldk - TriplyDB

Distinct and redundant functions of histone deacetylases HDAC1 and HDAC2 in proliferation and tumorigenesis.

Distinct and redundant functions of histone deacetylases HDAC1 and HDAC2 in proliferation and tumorigenesis.

http://www.wikidata.org/entity/Q42757408

about

Therapeutic efficacy of valproic acid in a combined monocrotaline and chronic hypoxia rat model of severe pulmonary hypertension Loss of the deubiquitylase BAP1 alters class I histone deacetylase expression and sensitivity of mesothelioma cells to HDAC inhibitors.Regulation of epithelial-mesenchymal transition through epigenetic and post-translational modifications TFPI1 mediates resistance to doxorubicin in breast cancer cells by inducing a hypoxic-like response LSD1 regulates pluripotency of embryonic stem/carcinoma cells through histone deacetylase 1-mediated deacetylation of histone H4 at lysine 16 A meta-analysis of multiple matched copy number and transcriptomics data sets for inferring gene regulatory relationships.Minireview: The versatile roles of lysine deacetylases in steroid receptor signaling HDAC2 overexpression correlates with aggressive clinicopathological features and DNA-damage response pathway of breast cancer.Histone deacetylase inhibition synergistically enhances pemetrexed cytotoxicity through induction of apoptosis and autophagy in non-small cell lung cancer.Small-molecular modulators of cancer-associated epigenetic mechanisms.HDAC1 and HDAC2 restrain the intestinal inflammatory response by regulating intestinal epithelial cell differentiation.Inference of interactions between chromatin modifiers and histone modifications: from ChIP-Seq data to chromatin-signaling HDACs Regulate miR-133a Expression in Pressure Overload-Induced Cardiac Fibrosis.Phospho-ΔNp63α/microRNA feedback regulation in squamous carcinoma cells upon cisplatin exposure The role of HDAC2 in chromatin remodelling and response to chemotherapy in ovarian cancer.Tcf21 regulates the specification and maturation of proepicardial cells.Acetylation dynamics of human nuclear proteins during the ionizing radiation-induced DNA damage response HDAC1 and HDAC2 in mouse oocytes and preimplantation embryos: Specificity versus compensation.Histone deacetylase regulation of ATM-mediated DNA damage signaling.The NuRD complex cooperates with DNMTs to maintain silencing of key colorectal tumor suppressor genes Mathematical model of dynamic protein interactions regulating p53 protein stability for tumor suppression.Class I HDACs specifically regulate E-cadherin expression in human renal epithelial cells.HDAC2 regulates cell proliferation, cell cycle progression and cell apoptosis in esophageal squamous cell carcinoma EC9706 cells.Targeting class I histone deacetylases in cancer therapy.Transcription and beyond: the role of mammalian class I lysine deacetylases Overexpression of histone deacetylase 2 predicts unfavorable prognosis in human gallbladder carcinoma.Inhibition of histone deacetylase 1 or 2 reduces induced cytokine expression in microglia through a protein synthesis independent mechanism.Genetic compensation: A phenomenon in search of mechanisms.Subcellular Distribution of HDAC1 in Neurotoxic Conditions Is Dependent on Serine Phosphorylation.A single allele of Hdac2 but not Hdac1 is sufficient for normal mouse brain development in the absence of its paralog.Pre-clinical characterization of 4SC-202, a novel class I HDAC inhibitor, against colorectal cancer cells.Phenotypic impact of deregulated expression of class I histone deacetylases in urothelial cell carcinoma of the bladder.A role for paralog-specific sumoylation in histone deacetylase 1 stability.Histone Deacetylase 2 Is a Component of Influenza A Virus-Induced Host Antiviral Response.The histone deacetylase Hdac1 regulates inflammatory signalling in intestinal epithelial cells Protein kinase CK2 regulates the dimerization of histone deacetylase 1 (HDAC1) and HDAC2 during mitosis.Roles of histone deacetylases in epigenetic regulation: emerging paradigms from studies with inhibitors Histone deacetylation inhibition in pulmonary hypertension: therapeutic potential of valproic acid and suberoylanilide hydroxamic acid.Histone deacetylase 1 and 2 are essential for murine neural crest proliferation, pharyngeal arch development, and craniofacial morphogenesis.TOPK Promotes Microglia/Macrophage Polarization towards M2 Phenotype via Inhibition of HDAC1 and HDAC2 Activity after Transient Cerebral Ischemia.

P2860

Q27316522-EDC155B8-1726-4D7E-8B31-C286B87469BD Q27853165-0EB4260F-2E39-4417-AF9E-5A826B576497 Q28076697-24F8166A-0DB6-48C7-B639-C67A151B04D0 Q28539226-B9A4A971-8B5D-4D8E-9A1C-4E8F2F64AAC0 Q28593421-F0B648FE-E1F9-43EA-B6D2-968482B9CC0A Q30844284-78C492BB-87B8-492F-BDF4-8639F612E4C5 Q33632070-7FBDA4F2-21F9-4E1D-8CC2-D91D1CAFF95E Q33733042-EBDC4E9D-DE1B-494C-9F47-CA6C49B6DF90 Q34346813-B886BA9B-806F-468F-91E3-AE28E776EA2A Q34628002-94CC785D-20AE-4482-B418-02E10A271666 Q34989302-7AD5294B-B8D6-44FD-8B46-D519EE8AA03D Q35441409-6585971D-61DD-4D77-A98A-C1F6B515952D Q36296735-87E20CE8-F6C7-48CB-B775-569B8BB4EC6E Q36674365-8EE87888-9AE0-4A47-9443-549E4452405A Q36782553-15781397-BB78-4533-A77F-EE28F85A8095 Q36842821-F3BF39B2-4646-4958-B336-4C4EB12E63BD Q37018228-C8973F3C-A7EA-4A17-870B-2981C7E02C8E Q37098834-42537C0D-B8F3-444D-A9F7-DAB81F775B30 Q37291739-2B90F428-9383-4A72-87AE-F2B773D9DF1E Q37445834-C42DE09E-7999-4581-88E7-35B22BDCFF82 Q37465881-C1EB449E-0689-4D0A-8DAC-7EE3874624E3 Q37466825-6BDB10E3-966B-41CE-A52C-9FEE5A48534F Q37594003-DF6CA775-BA15-48AD-B63B-6F5264AAD983 Q38051736-C6EAE18C-F8AA-4DCC-845D-2A4610F5E469 Q38156341-6BBBDF5F-443C-4F01-806F-088D23256561 Q38398975-A8542BB8-CBEA-4AAA-A406-782EBA903F89 Q38630674-98519497-6B3F-4A90-B5BA-6F9C915A8C59 Q38680916-8CC93E6F-C2DC-4F48-8FA2-10ADE12C2636 Q38701633-861F1167-C3FB-4415-B47C-157D366EFDA3 Q38712941-510FB92C-96B2-4CC7-A904-3031B48DFB21 Q38797637-AB30AE8D-5367-4D0B-9C15-8C1C5F9BDA9B Q39051488-F4C3D811-1F4A-4081-84F0-E2C4722BA442 Q39091679-6CED5FA3-3FE7-499C-97B0-1BE3AED55C6F Q40097305-DF1DBA60-595B-49CE-99DD-3CF675514173 Q41531051-FFC146D8-CEF0-4AB7-8AAC-1FF49FBD4B33 Q42144052-2DC87EC6-48AD-4F18-8B0F-4A90F9973462 Q42555454-2F6F9459-E287-41DD-BDB9-730A21D95EE5 Q42688359-50EAB7AE-CEE0-4D48-8965-2120C01621FC Q48268665-CBB854D1-1400-4953-8132-94644AC87AE6 Q55040197-5115F0FB-7079-4C63-8FCC-8A5806D9DDD4

P2860

Distinct and redundant functions of histone deacetylases HDAC1 and HDAC2 in proliferation and tumorigenesis.

http://www.wikidata.org/entity/Q42757408

description

2011 nî lūn-bûn

@nan

2011年の論文

@ja

2011年論文

@yue

2011年論文

@zh-hant

2011年論文

@zh-hk

2011年論文

@zh-mo

2011年論文

@zh-tw

2011年论文

@wuu

2011年论文

@zh

2011年论文

@zh-cn

name

Distinct and redundant functio ...... oliferation and tumorigenesis.

@en

Distinct and redundant functio ...... oliferation and tumorigenesis.

@nl

type

label

Distinct and redundant functio ...... oliferation and tumorigenesis.

@en

Distinct and redundant functio ...... oliferation and tumorigenesis.

@nl

prefLabel

Distinct and redundant functio ...... oliferation and tumorigenesis.

@en

Distinct and redundant functio ...... oliferation and tumorigenesis.

@nl

P1433

Q42757408-97E571BB-EA73-469A-94E4-61BC80352EF0

P1476

Q42757408-32D8B2AE-1E2D-4415-909E-D1D48D11D0F0

P2093

Q42757408-63F845E0-E0EB-44A3-892F-C750E9936316

Q42757408-83DEFCBF-1EAB-4323-AFD3-48FD8AB78093

Q42757408-AAF1F083-E974-412D-94D8-8B2ACB2344B1

P2860

Q42757408-066E77A2-5BE6-43D8-9FB0-0993A320BACE

Q42757408-0691540B-4A82-49FA-BF9A-326F8BC4841D

Q42757408-1464A50D-E545-4EC1-AA28-EDB1530AECD5

Q42757408-17814F8D-A8B3-4E20-BA7C-4D4063AA0FB8

Q42757408-19C93147-F64E-4CC2-B9B7-994D9902503C

Q42757408-1BAED074-CF40-4B3E-8B8A-1A9E188118C2

Q42757408-2245DA87-16B1-4A93-93C3-233764F504FC

Q42757408-234835CE-6183-4843-9693-97B293FCD6C9

Q42757408-25A8B24E-A2F0-40AA-91D2-6EF678C3E1B8

Q42757408-2B9442A7-E945-4B8D-85BD-C40877AD3483

P304

Q42757408-FA7E3EB1-6DE7-446B-8B5F-6DA021D859A0

P31

Q42757408-16877212-2BAF-4272-9D3E-5C5589E631EC

P356

Q42757408-91C136D6-5E07-49A6-A93C-D36FD8504D0C

P433

Q42757408-25CD84B4-6D4F-4918-A5AC-3923A3AE183D

P478

Q42757408-B8AD6FA1-D43E-4916-98CF-7E4D73A53A20

P50

Q42757408-134CE58F-F0FD-4855-B0F0-2529B2A8C866

Q42757408-3C173AF2-EC2C-4B9C-9C6D-C878DAD7A54B

Q42757408-89FA4E9D-A398-4849-9D7C-9E051F0C4A7B

Q42757408-CB5C78AD-75BB-489B-BF1D-DB3BC218CF88

P577

Q42757408-27459319-DD8E-46F2-B3B6-AB5FD1FFE12B

P5875

Q42757408-C7AF45D8-0D54-4A28-AC0B-79443C9DA500

P698

Q42757408-D10F2C7B-4D92-4BAB-9296-255043C64426

P932

Q42757408-2DF89EA7-2E1A-4039-BBC6-2D9970A6C966

P356

P1433

P1476

Distinct and redundant functio ...... roliferation and tumorigenesis

@en

P2093

Astrid Hagelkruys

http://www.w3.org/2001/XMLSchema#string

Jennifer Jurkin

http://www.w3.org/2001/XMLSchema#string

Reinhard Grausenburger

http://www.w3.org/2001/XMLSchema#string

P2860

Class I histone deacetylase expression has independent prognostic impact in human colorectal cancer: specific role of class I histone deacetylases in vitro and in vivo

HDAC2 regulates chromatin plasticity and enhances DNA vulnerability

Selective inhibition of histone deacetylase 2 silences progesterone receptor-mediated signaling

A truncating mutation of HDAC2 in human cancers confers resistance to histone deacetylase inhibition

Histone deacetylases (HDACs): characterization of the classical HDAC family

Lysine acetylation: codified crosstalk with other posttranslational modifications

Retinoblastoma protein represses transcription by recruiting a histone deacetylase

Identification of mouse histone deacetylase 1 as a growth factor-inducible gene

HDAC1 and HDAC2 regulate oligodendrocyte differentiation by disrupting the beta-catenin-TCF interaction

Histone deacetylases 1 and 2 control the progression of neural precursors to neurons during brain development

P304

406-412

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.4161/CC.10.3.14712

http://www.w3.org/2001/XMLSchema#string

P433

3

http://www.w3.org/2001/XMLSchema#string

P478

10

http://www.w3.org/2001/XMLSchema#string

P50

Gordin Zupkovitz

P577

2011-02-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

49788527

http://www.w3.org/2001/XMLSchema#string

P698

21270520

http://www.w3.org/2001/XMLSchema#string

P932

3115015

http://www.w3.org/2001/XMLSchema#string