Thrombospondin-1: an islet endothelial cell signal of importance for β-cell function. - Wikidata - awgldk - TriplyDB

Thrombospondin-1: an islet endothelial cell signal of importance for β-cell function.

Thrombospondin-1: an islet endothelial cell signal of importance for β-cell function.

http://www.wikidata.org/entity/Q42770584

about

Angiocrine functions of organ-specific endothelial cells Sustained beta-cell dysfunction but normalized islet mass in aged thrombospondin-1 deficient mice.Revisiting the matricellular concept.Thrombospondin-1 induction in the diabetic myocardium stabilizes the cardiac matrix in addition to promoting vascular rarefaction through angiopoietin-2 upregulation.Betatrophin in Diabetes Mellitus: the Epidemiological Evidence in Humans.Lung-Derived Microscaffolds Facilitate Diabetes Reversal after Mouse and Human Intraperitoneal Islet Transplantation Angiopoetin-2 Signals Do Not Mediate the Hypervascularization of Islets in Type 2 Diabetes.Normal glucose uptake in the brain and heart requires an endothelial cell-specific HIF-1α-dependent function.Peri-adipocyte ECM remodeling in obesity and adipose tissue fibrosis.Decreased Serum Thrombospondin-1 Levels in Pancreatic Cancer Patients Up to 24 Months Prior to Clinical Diagnosis: Association with Diabetes Mellitus.Thrombospondin-1 regulates adiposity and metabolic dysfunction in diet-induced obesity enhancing adipose inflammation and stimulating adipocyte proliferation The therapeutic role of endothelial progenitor cells in Type 1 diabetes mellitus.Endothelial dysfunction in (pre)diabetes: characteristics, causative mechanisms and pathogenic role in type 2 diabetes.Accessory cells for β-cell transplantation.Markers of Islet Endothelial Dysfunction Occur in Male B6.BKS(D)-Leprdb/J Mice and May Contribute to Reduced Insulin Release.Improving islet engraftment by gene therapy The islet endothelial cell: a novel contributor to beta cell secretory dysfunction in diabetes.Exploring inter-organ crosstalk to uncover mechanisms that regulate β-cell function and mass.Intra-islet endothelial cell and β-cell crosstalk: Implication for islet cell transplantation.The role of thrombospondin (TSP)-1 in obesity and diabetes.Imatinib mesylate stimulates low-density lipoprotein receptor-related protein 1-mediated ERK phosphorylation in insulin-producing cells.Activin receptor-like kinase 5 inhibition reverses impairment of endothelial cell viability by endogenous islet mesenchymal stromal cells.Thrombospondin 1 protects pancreatic β-cells from lipotoxicity via the PERK-NRF2 pathway.Alteration in cellular turnover and progenitor cell population in lacrimal glands from thrombospondin 1-/- mice, a model of dry eye.Pancreatic β-cell protection from inflammatory stress by the endoplasmic reticulum proteins thrombospondin 1 and mesencephalic astrocyte-derived neutrotrophic factor (MANF).

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Thrombospondin-1: an islet endothelial cell signal of importance for β-cell function.

http://www.wikidata.org/entity/Q42770584

description

2011 nî lūn-bûn

@nan

2011年の論文

@ja

2011年論文

@yue

2011年論文

@zh-hant

2011年論文

@zh-hk

2011年論文

@zh-mo

2011年論文

@zh-tw

2011年论文

@wuu

2011年论文

@zh

2011年论文

@zh-cn

name

Thrombospondin-1: an islet endothelial cell signal of importance for β-cell function.

@en

Thrombospondin-1: an islet endothelial cell signal of importance for β-cell function.

@nl

type

label

Thrombospondin-1: an islet endothelial cell signal of importance for β-cell function.

@en

Thrombospondin-1: an islet endothelial cell signal of importance for β-cell function.

@nl

prefLabel

Thrombospondin-1: an islet endothelial cell signal of importance for β-cell function.

@en

Thrombospondin-1: an islet endothelial cell signal of importance for β-cell function.

@nl

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P1476

Thrombospondin-1: an islet endothelial cell signal of importance for β-cell function

@en

P2093

Dariush Mokhtari

http://www.w3.org/2001/XMLSchema#string

Jack Lawler

http://www.w3.org/2001/XMLSchema#string

Johan Olerud

http://www.w3.org/2001/XMLSchema#string

Magnus Johansson

http://www.w3.org/2001/XMLSchema#string

Nils Welsh

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Per-Ola Carlsson

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P2860

Conditional expression of Smad7 in pancreatic beta cells disrupts TGF-beta signaling and induces reversible diabetes mellitus

Activation of latent TGF-beta by thrombospondin-1: mechanisms and physiology

Thrombospondin-1 is a major activator of TGF-beta1 in vivo

Low revascularization of experimentally transplanted human pancreatic islets.

Donor islet endothelial cells participate in formation of functional vessels within pancreatic islet grafts.

Changes in gene expression in beta cells after islet isolation and transplantation using laser-capture microdissection.

A tumor suppressor-dependent inhibitor of angiogenesis is immunologically and functionally indistinguishable from a fragment of thrombospondin

Overexpression of monocarboxylate transporter and lactate dehydrogenase alters insulin secretory responses to pyruvate and lactate in beta cells

Critical reduction in beta-cell mass results in two distinct outcomes over time. Adaptation with impaired glucose tolerance or decompensated diabetes.

Phagocyte recognition of cells undergoing apoptosis.

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1946-1954

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10.2337/DB10-0277

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7

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60

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Gustaf Christoffersson

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2011-05-26T00:00:00Z

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51169581

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21617177

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3121439

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