High-affinity receptor-mediated internalization and degradation of interleukin 2 in human T cells.
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Chloroquine inhibits T cell proliferation by interfering with IL-2 production and responsivenessPhosphorylation and internalization of gp130 occur after IL-6 activation of Jak2 kinase in hepatocytesRegulation of interleukin 2 receptor alpha subunit (Tac or CD25 antigen) gene expression: binding of inducible nuclear proteins to discrete promoter sequences correlates with transcriptional activation.Evidence for two extracellular domains in the human interleukin-2 receptor: localization of IL-2 binding.Loss of hippocampal CA3 pyramidal neurons in mice lacking STAM1.Activation of interleukin 2 and interleukin 2 receptor (Tac) promoter expression by the trans-activator (tat) gene product of human T-cell leukemia virus, type I.Increased concentrations of interleukin 1 beta, interleukin-2, and soluble interleukin-2 receptors in endoscopical mucosal biopsy specimens with active inflammatory bowel diseasePlasma interleukin-2 and a soluble/shed interleukin-2 receptor in serum of patients with Crohn's disease. Effect of cyclosporin.Interleukin 2 binding molecule distinct from the Tac protein: analysis of its role in formation of high-affinity receptors.Differential internalization of hu14.18-IL2 immunocytokine by NK and tumor cell: impact on conjugation, cytotoxicity, and targeting.Men with low vitamin A stores respond adequately to primary yellow fever and secondary tetanus toxoid vaccination.Transcriptional regulation of two cytotoxic T lymphocyte-specific serine protease genes.Cytokines in inflammatory bowel disease.Interleukin-2 receptor-directed immunosuppressive therapies: antibody- or cytokine-based targeting molecules.Interferon-alpha and interleukin 2 synergistically enhance basic fibroblast growth factor synthesis and induce release, promoting endothelial cell growth.Constitutive secretion of soluble interleukin-2 receptor by human T cell lymphoma xenografted into SCID mice. Correlation of tumor volume with concentration of tumor-derived soluble interleukin-2 receptor in body fluids of the host mice.Affinity of IL-2 receptors and proliferation of mitogen activated lymphocytes in Hodgkin's diseaseReconstitution of functional interleukin 2 receptor complexes on fibroblastoid cells: involvement of the cytoplasmic domain of the gamma chain in two distinct signaling pathwaysInterleukin 2 high-affinity receptor expression requires two distinct binding proteins.Internalization of interleukin 2 is mediated by the beta chain of the high-affinity interleukin 2 receptorInterleukin 2 receptor-targeted cytotoxicity. Interleukin 2 receptor-mediated action of a diphtheria toxin-related interleukin 2 fusion proteinInteractions between receptors for interleukin 2 and interleukin 4 on lines of helper T cells (HT-2) and B lymphoma cells (BCL1).Immunotoxins and cytokine toxin fusion proteins.Protein engineering of DAB-IL-2 fusion toxins to increase biologic potency.Demonstration of a non-Tac peptide that binds interleukin 2: a potential participant in a multichain interleukin 2 receptor complex.Photoaffinity labeling of ATP and NAD+ binding sites on recombinant human interleukin 2.An overview of the human interleukin-2 receptor: molecular, biochemical, and functional properties.The human interleukin-2 receptor. Recent studies of structure and regulation.Clonal and functional analysis for the augmentation of tumour-infiltrating lymphocytes by interleukin 4.Expression of novel interleukin 2 binding molecules and their functional roles in human B cell differentiation.Transient induction of IL-2 receptor in cultured T cell lines by HTLV-1 LTR-linked tax-1 gene.Increased endosomal sorting of ligand to recycling enhances potency of an interleukin-2 analog.Purified protein from Salmonella typhimurium inhibits the interleukin-2 response of murine splenic T-lymphocytes activated with anti-CD3 antibody.Endocytosis of interleukin 2 receptors in human T lymphocytes: distinct intracellular localization and fate of the receptor alpha, beta, and gamma chainsDistinct downstream signaling mechanism between erythropoietin receptor and interleukin-2 receptor.Reconstituted human granulocyte-macrophage colony-stimulating factor receptor transduces growth-promoting signals in mouse NIH 3T3 cells: comparison with signalling in BA/F3 pro-B cells.Intermolecular cystine-bonding of murine interleukin 2 indicates that ligand dimerization is important for the formation of the high-affinity receptor complex.Binding and internalization of interleukin 1 by T cells. Direct evidence for high- and low-affinity classes of interleukin 1 receptor.Characterization of interleukin 2-stimulated phosphorylation of 67 and 63 kDa proteins in human T-cells.Contrasting interleukin 2 binding properties of the alpha (p55) and beta (p70) protein subunits of the human high-affinity interleukin 2 receptor.
P2860
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P2860
High-affinity receptor-mediated internalization and degradation of interleukin 2 in human T cells.
description
1986 nî lūn-bûn
@nan
1986年の論文
@ja
1986年論文
@yue
1986年論文
@zh-hant
1986年論文
@zh-hk
1986年論文
@zh-mo
1986年論文
@zh-tw
1986年论文
@wuu
1986年论文
@zh
1986年论文
@zh-cn
name
High-affinity receptor-mediate ...... nterleukin 2 in human T cells.
@en
High-affinity receptor-mediate ...... nterleukin 2 in human T cells.
@nl
type
label
High-affinity receptor-mediate ...... nterleukin 2 in human T cells.
@en
High-affinity receptor-mediate ...... nterleukin 2 in human T cells.
@nl
prefLabel
High-affinity receptor-mediate ...... nterleukin 2 in human T cells.
@en
High-affinity receptor-mediate ...... nterleukin 2 in human T cells.
@nl
P2093
P2860
P356
P1476
High-affinity receptor-mediate ...... nterleukin 2 in human T cells.
@en
P2093
P2860
P304
P356
10.1084/JEM.163.3.550
P407
P577
1986-03-01T00:00:00Z