A defective response to Hedgehog signaling in disorders of cholesterol biosynthesis. - Wikidata - awgldk - TriplyDB

A defective response to Hedgehog signaling in disorders of cholesterol biosynthesis.

A defective response to Hedgehog signaling in disorders of cholesterol biosynthesis.

http://www.wikidata.org/entity/Q42803883

about

Repression of smoothened by patched-dependent (pro-)vitamin D3 secretion Immunohistochemical analysis of Sonic hedgehog signalling in normal human urinary tract development RAB23 mutations in Carpenter syndrome imply an unexpected role for hedgehog signaling in cranial-suture development and obesity The hedgehog receptor patched is involved in cholesterol transport Recent insights into the Smith-Lemli-Opitz syndrome.Oxysterols stimulate Sonic hedgehog signal transduction and proliferation of medulloblastoma cells The molecular biology, biochemistry, and physiology of human steroidogenesis and its disorders Pathogenesis of permeability barrier abnormalities in the ichthyoses: inherited disorders of lipid metabolism Nanostructure-initiator mass spectrometry (NIMS) imaging of brain cholesterol metabolites in Smith-Lemli-Opitz syndrome Late gestational lung hypoplasia in a mouse model of the Smith-Lemli-Opitz syndrome Holoprosencephaly: signaling interactions between the brain and the face, the environment and the genes, and the phenotypic variability in animal models and humans Cholesterol metabolism is required for intracellular hedgehog signal transduction in vivo Lipoprotein particles are required for Hedgehog and Wingless signalling Structural basis of Smoothened regulation by its extracellular domains Itraconazole, a commonly used antifungal that inhibits Hedgehog pathway activity and cancer growth A mutation in the mouse ttc26 gene leads to impaired hedgehog signaling Ethanol induces cholesterol efflux and up-regulates ATP-binding cassette cholesterol transporters in fetal astrocytes.Inhibition of HMG CoA reductase reveals an unexpected role for cholesterol during PGC migration in the mouse.Inositol hexakisphosphate kinase-2 acts as an effector of the vertebrate Hedgehog pathway.In vivo analysis of compound activity and mechanism of action using epistasis in Drosophila.Hedgehog signaling and response to cyclopamine differ in epithelial and stromal cells in benign breast and breast cancer.Smoothened goes molecular: new pieces in the hedgehog signaling puzzle Quantitative proteomics analysis of inborn errors of cholesterol synthesis: identification of altered metabolic pathways in DHCR7 and SC5D deficiency Formation of 7-dehydrocholesterol-containing membrane rafts in vitro and in vivo, with relevance to the Smith-Lemli-Opitz syndrome.Smith-Lemli-Opitz syndrome and inborn errors of cholesterol synthesis: summary of the 2007 SLO/RSH Foundation scientific conference sponsored by the National Institutes of Health.Lipid modifications of Sonic hedgehog ligand dictate cellular reception and signal response.NPC1L1 and cholesterol transport Abnormal sterol metabolism in holoprosencephaly Recent advances on skin-resident stem/progenitor cell functions in skin regeneration, aging and cancers and novel anti-aging and cancer therapies.Small-molecule modulators of the Sonic Hedgehog signaling pathway.Molecular mechanisms of Sonic hedgehog mutant effects in holoprosencephaly.Selective identification of hedgehog pathway antagonists by direct analysis of smoothened ciliary translocation.Characterization of two ectrodactyly-associated translocation breakpoints separated by 2.5 Mb on chromosome 2q14.1-q14.2.Hypomorphic temperature-sensitive alleles of NSDHL cause CK syndrome Malformation syndromes caused by disorders of cholesterol synthesis.Reduced cholesterol levels impair Smoothened activation in Smith-Lemli-Opitz syndrome.Mutations causing Greenberg dysplasia but not Pelger anomaly uncouple enzymatic from structural functions of a nuclear membrane protein.Enhanced placental cholesterol efflux by fetal HDL in Smith-Lemli-Opitz syndrome.Conditional ablation of Pten in osteoprogenitors stimulates FGF signaling Cholesterol biosynthesis and homeostasis in regulation of the cell cycle.

P2860

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P2860

A defective response to Hedgehog signaling in disorders of cholesterol biosynthesis.

http://www.wikidata.org/entity/Q42803883

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2003 nî lūn-bûn

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2003年の論文

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2003年论文

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2003年论文

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2003年论文

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name

A defective response to Hedgehog signaling in disorders of cholesterol biosynthesis.

@en

A defective response to Hedgehog signaling in disorders of cholesterol biosynthesis.

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type

label

A defective response to Hedgehog signaling in disorders of cholesterol biosynthesis.

@en

A defective response to Hedgehog signaling in disorders of cholesterol biosynthesis.

@nl

prefLabel

A defective response to Hedgehog signaling in disorders of cholesterol biosynthesis.

@en

A defective response to Hedgehog signaling in disorders of cholesterol biosynthesis.

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Nature Genetics

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A defective response to Hedgehog signaling in disorders of cholesterol biosynthesis.

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Forbes D Porter

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Jussi Taipale

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Michael K Cooper

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Patrycja A Krakowiak

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Philip A Beachy

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Richard I Kelley

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Ruoyu Gong

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Christopher A Wassif

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