Desensitization of Ras activation by a feedback disassociation of the SOS-Grb2 complex.
about
Regulation of Sos activity by intramolecular interactions.Insulin regulates the dynamic balance between Ras and Rap1 signaling by coordinating the assembly states of the Grb2-SOS and CrkII-C3G complexes.The molecular basis of viral oncolysis: usurpation of the Ras signaling pathway by reovirusIEX-1: a new ERK substrate involved in both ERK survival activity and ERK activationIdentification of the mitogen-activated protein kinase phosphorylation sites on human Sos1 that regulate interaction with Grb2Tyrosine phosphorylation of Grb2-associated proteins correlates with phospholipase C gamma 1 activation in T cellsTCGAP, a multidomain Rho GTPase-activating protein involved in insulin-stimulated glucose transportA comprehensive pathway map of epidermal growth factor receptor signalingHematopoietic progenitor kinase 1 associates physically and functionally with the adaptor proteins B cell linker protein and SLP-76 in lymphocytesInteractions between Src homology (SH) 2/SH3 adapter proteins and the guanylnucleotide exchange factor SOS are differentially regulated by insulin and epidermal growth factorSignal transduction pathway of human fibroblast growth factor receptor 3. Identification of a novel 66-kDa phosphoproteinTumor promoter arsenite activates extracellular signal-regulated kinase through a signaling pathway mediated by epidermal growth factor receptor and Shc.Identification of sirm, a novel insulin-regulated SH3 binding protein that associates with Grb-2 and FYNIntersectin can regulate the Ras/MAP kinase pathway independent of its role in endocytosis.Differential interactions of the growth factor receptor-bound protein 2 N-SH3 domain with son of sevenless and dynamin. Potential role in the Ras-dependent signaling pathway.c-Raf-mediated inhibition of epidermal growth factor-stimulated cell migration.Systematic quantification of negative feedback mechanisms in the extracellular signal-regulated kinase (ERK) signaling network.Version control of pathway models using XML patchesComputational modelling of cancerous mutations in the EGFR/ERK signalling pathway.Insulin receptor isoform A, a newly recognized, high-affinity insulin-like growth factor II receptor in fetal and cancer cells.Identification of the mechanisms regulating the differential activation of the mapk cascade by epidermal growth factor and nerve growth factor in PC12 cells.The Ras/Rac guanine nucleotide exchange factor mammalian Son-of-sevenless interacts with PACSIN 1/syndapin I, a regulator of endocytosis and the actin cytoskeleton.Spatial cycles in G-protein crowd controlInhibition of insulin receptor catalytic activity by the molecular adapter Grb14.Logical analysis of timing-dependent receptor signalling specificity: application to the insulin receptor metabolic and mitogenic signalling pathways.Regulation of cell polarity during eukaryotic chemotaxis: the chemotactic compass.Dephosphorylation by default, a potential mechanism for regulation of insulin receptor substrate-1/2, Akt, and ERK1/2.A role for K-ras in conferring resistance to the MEK inhibitor, CI-1040.Insulin stimulation of a MEK-dependent but ERK-independent SOS protein kinaseCalcium-dependent immediate-early gene induction in lymphocytes is negatively regulated by p21Ha-rasInvolvement of JNK-mediated pathway in EGF-mediated protection against paclitaxel-induced apoptosis in SiHa human cervical cancer cells.A negative-feedback loop regulating ERK1/2 activation and mediated by RasGPR2 phosphorylation.Activation of extracellular signal-regulated kinase but not of p38 mitogen-activated protein kinase pathways in lymphocytes requires allosteric activation of SOS.PI3K-dependent cross-talk interactions converge with Ras as quantifiable inputs integrated by ErkDisabled-2 Determines Commitment of a Pre-adipocyte Population in Juvenile Mice.Mitogen-activated protein kinase/extracellular signal-regulated kinase 2 regulates cytoskeletal organization and chemotaxis via catalytic and microtubule-specific interactionsRegulation of ras exchange factors and cellular localization of ras activation by lipid messengers in T cells.Inferring Intracellular Signal Transduction Circuitry from Molecular Perturbation Experiments.Quantification of growth factor signaling and pathway cross talk by live-cell imaging.Signal integration and coincidence detection in the mitogen-activated protein kinase/extracellular signal-regulated kinase (ERK) cascade: concomitant activation of receptor tyrosine kinases and of LRP-1 leads to sustained ERK phosphorylation via dow
P2860
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P2860
Desensitization of Ras activation by a feedback disassociation of the SOS-Grb2 complex.
description
1995 nî lūn-bûn
@nan
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
1995年论文
@zh
1995年论文
@zh-cn
name
Desensitization of Ras activation by a feedback disassociation of the SOS-Grb2 complex.
@en
Desensitization of Ras activation by a feedback disassociation of the SOS-Grb2 complex.
@nl
type
label
Desensitization of Ras activation by a feedback disassociation of the SOS-Grb2 complex.
@en
Desensitization of Ras activation by a feedback disassociation of the SOS-Grb2 complex.
@nl
prefLabel
Desensitization of Ras activation by a feedback disassociation of the SOS-Grb2 complex.
@en
Desensitization of Ras activation by a feedback disassociation of the SOS-Grb2 complex.
@nl
P2093
P2860
P356
P1476
Desensitization of Ras activation by a feedback disassociation of the SOS-Grb2 complex.
@en
P2093
A R Saltiel
G A Koretzky
J E Pessin
S B Waters
P2860
P304
20883-20886
P356
10.1074/JBC.270.36.20883
P407
P577
1995-09-01T00:00:00Z