Insulin-stimulated disassociation of the SOS-Grb2 complex
about
A novel, multifuntional c-Cbl binding protein in insulin receptor signaling in 3T3-L1 adipocytesRegulation of Sos activity by intramolecular interactions.Insulin regulates the dynamic balance between Ras and Rap1 signaling by coordinating the assembly states of the Grb2-SOS and CrkII-C3G complexes.Fyn-dependent regulation of energy expenditure and body weight is mediated by tyrosine phosphorylation of LKB1Identification of the mitogen-activated protein kinase phosphorylation sites on human Sos1 that regulate interaction with Grb2Extracellular signal-regulated kinase activated by epidermal growth factor and cell adhesion interacts with and phosphorylates vinexinInteractions between Src homology (SH) 2/SH3 adapter proteins and the guanylnucleotide exchange factor SOS are differentially regulated by insulin and epidermal growth factorSignal transduction pathway of human fibroblast growth factor receptor 3. Identification of a novel 66-kDa phosphoproteinIdentification of sirm, a novel insulin-regulated SH3 binding protein that associates with Grb-2 and FYNInsulin enhances growth hormone induction of the MEK/ERK signaling pathwayMechanisms through which Sos-1 coordinates the activation of Ras and Rac.Vinexin forms a signaling complex with Sos and modulates epidermal growth factor-induced c-Jun N-terminal kinase/stress-activated protein kinase activities.Evidence that DOCK180 up-regulates signals from the CrkII-p130(Cas) complex.A potential SH3 domain-binding site in the Crk SH2 domain.Interactions of Cbl with two adapter proteins, Grb2 and Crk, upon T cell activation.Divergent mechanisms for homologous desensitization of p21ras by insulin and growth factors.The Grb2 adaptor.c-Raf-mediated inhibition of epidermal growth factor-stimulated cell migration.Insulin activates a PD 098059-sensitive kinase that is involved in the regulation of p70S6K and PHAS-I.Disabled-2 inactivation is an early step in ovarian tumorigenicity.Osmotic shock inhibits insulin signaling by maintaining Akt/protein kinase B in an inactive dephosphorylated stateSyntaxin4 interacting protein (Synip) binds phosphatidylinositol (3,4,5) triphosphate.Hormonal induction and roles of Disabled-2 in lactation and involution.p27Kip1 inhibition of GRB2-SOS formation can regulate Ras activation.Discrimination of GLUT4 vesicle trafficking from fusion using a temperature-sensitive Munc18c mutantFeedback regulation of lymphocyte signalling.Motogenic and morphogenic activity of epithelial receptor tyrosine kinases.Insulin stimulation of a MEK-dependent but ERK-independent SOS protein kinaseFeedback activation of neurofibromin terminates growth factor-induced Ras activation.GEFs in growth factor signaling.Prolactin stimulates serine/tyrosine phosphorylation and formation of heterocomplexes of multiple Stat5 isoforms in Nb2 lymphocytes.Requirement for phosphatidylinositol 3-kinase in epidermal growth factor-induced AP-1 transactivation and transformation in JB6 P+ cells.T cell receptor-induced phosphorylation of Sos requires activity of CD45, Lck, and protein kinase C, but not ERK.Regulation of epidermal growth factor receptor signaling by phosphorylation of the ras exchange factor hSOS1.Synergistic effects of insulin and phorbol ester on mitogen-activated protein kinase in Rat-1 HIR cells.Mitogen-activated protein kinase kinase inhibition does not block the stimulation of glucose utilization by insulin.Multiple decisive phosphorylation sites for the negative feedback regulation of SOS1 via ERK.Insulin and epidermal growth factor stimulate a conformational change in Rap1 and dissociation of the CrkII-C3G complex.Feedback regulation of Raf-1 and mitogen-activated protein kinase (MAP) kinase kinases 1 and 2 by MAP kinase phosphatase-1 (MKP-1).Different pathways of postreceptor desensitization following chronic insulin treatment and in cells overexpressing constitutively active insulin receptors.
P2860
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P2860
Insulin-stimulated disassociation of the SOS-Grb2 complex
description
1995 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
1995 թվականի մայիսին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 1995
@ast
im Mai 1995 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 1995/05/01)
@sk
vědecký článek publikovaný v roce 1995
@cs
wetenschappelijk artikel (gepubliceerd op 1995/05/01)
@nl
наукова стаття, опублікована в травні 1995
@uk
مقالة علمية (نشرت في مايو 1995)
@ar
name
Insulin-stimulated disassociation of the SOS-Grb2 complex
@ast
Insulin-stimulated disassociation of the SOS-Grb2 complex
@en
Insulin-stimulated disassociation of the SOS-Grb2 complex
@nl
type
label
Insulin-stimulated disassociation of the SOS-Grb2 complex
@ast
Insulin-stimulated disassociation of the SOS-Grb2 complex
@en
Insulin-stimulated disassociation of the SOS-Grb2 complex
@nl
prefLabel
Insulin-stimulated disassociation of the SOS-Grb2 complex
@ast
Insulin-stimulated disassociation of the SOS-Grb2 complex
@en
Insulin-stimulated disassociation of the SOS-Grb2 complex
@nl
P2093
P2860
P356
P1476
Insulin-stimulated disassociation of the SOS-Grb2 complex
@en
P2093
J. E. Pessin
K. Yamauchi
S. B. Waters
P2860
P304
P356
10.1128/MCB.15.5.2791
P407
P577
1995-05-01T00:00:00Z