Sphingosine kinase-1 mediates BCR/ABL-induced upregulation of Mcl-1 in chronic myeloid leukemia cells.
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Aclacinomycin A sensitizes K562 chronic myeloid leukemia cells to imatinib through p38MAPK-mediated erythroid differentiationThe apoptotic mechanism of action of the sphingosine kinase 1 selective inhibitor SKI-178 in human acute myeloid leukemia cell lines.Re-configuration of sphingolipid metabolism by oncogenic transformation.Sphingosine kinase 1 in cancer.Apoptotic sphingolipid ceramide in cancer therapy.Sphingosine kinase-1 and sphingosine 1-phosphate receptor 2 mediate Bcr-Abl1 stability and drug resistance by modulation of protein phosphatase 2A.Targeting sphingosine-1-phosphate in hematologic malignanciesCommunication between host organism and cancer cells is transduced by systemic sphingosine kinase 1/sphingosine 1-phosphate signalling to regulate tumour metastasis.Apoptosis induces expression of sphingosine kinase 1 to release sphingosine-1-phosphate as a "come-and-get-me" signal.A selective sphingosine kinase 1 inhibitor integrates multiple molecular therapeutic targets in human leukemia.Regulation and functions of sphingosine kinases in the brainTherapeutic applications of bioactive sphingolipids in hematological malignancies.Oncogenic properties of sphingosine kinases in haematological malignancies.Therapeutic potential of targeting sphingosine kinases and sphingosine 1-phosphate in hematological malignancies.Activin A induction of erythroid differentiation sensitizes K562 chronic myeloid leukemia cells to a subtoxic concentration of imatinib.Prokineticin-1/endocrine gland-derived vascular endothelial growth factor is a survival factor for human multiple myeloma cells.MPL W515L expression induces TGFβ secretion and leads to an increase in chemokinesis via phosphorylation of THOC5.Hepatopoietin Cn reduces ethanol-induced hepatoxicity via sphingosine kinase 1 and sphingosine 1-phosphate receptors.Increased radiation sensitivity of head and neck squamous cell carcinoma with sphingosine kinase 1 inhibition.Targeting glucosylceramide synthase sensitizes imatinib-resistant chronic myeloid leukemia cells via endogenous ceramide accumulation.
P2860
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P2860
Sphingosine kinase-1 mediates BCR/ABL-induced upregulation of Mcl-1 in chronic myeloid leukemia cells.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Sphingosine kinase-1 mediates ...... hronic myeloid leukemia cells.
@en
Sphingosine kinase-1 mediates ...... hronic myeloid leukemia cells.
@nl
type
label
Sphingosine kinase-1 mediates ...... hronic myeloid leukemia cells.
@en
Sphingosine kinase-1 mediates ...... hronic myeloid leukemia cells.
@nl
prefLabel
Sphingosine kinase-1 mediates ...... hronic myeloid leukemia cells.
@en
Sphingosine kinase-1 mediates ...... hronic myeloid leukemia cells.
@nl
P2093
P356
P1433
P1476
Sphingosine kinase-1 mediates ...... hronic myeloid leukemia cells.
@en
P2093
P2888
P304
P356
10.1038/SJ.ONC.1210587
P407
P577
2007-06-18T00:00:00Z
P5875
P6179
1023452761