Rapamycin inhibition of the G1 to S transition is mediated by effects on cyclin D1 mRNA and protein stability.
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The regulation of cyclin D1 degradation: roles in cancer development and the potential for therapeutic inventionTSC1 sets the rate of ribosome export and protein synthesis through nucleophosmin translationTranslational Upregulation of an Individual p21Cip1 Transcript Variant by GCN2 Regulates Cell Proliferation and Survival under Nutrient StressSignaling by target of rapamycin proteins in cell growth controlRapamycin potentiates transforming growth factor beta-induced growth arrest in nontransformed, oncogene-transformed, and human cancer cells.mTOR-dependent activation of the transcription factor TIF-IA links rRNA synthesis to nutrient availabilityTargeting the mTOR signaling network for cancer therapyHIV-1 expression induces cyclin D1 expression and pRb phosphorylation in infected podocytes: cell-cycle mechanisms contributing to the proliferative phenotype in HIV-associated nephropathy.The proteasome inhibitor MG-132 sensitizes PC-3 prostate cancer cells to ionizing radiation by a DNA-PK-independent mechanism.Degradation of B-Myb by ubiquitin-mediated proteolysis: involvement of the Cdc34-SCF(p45Skp2) pathwaySalicylate-induced growth arrest is associated with inhibition of p70s6k and down-regulation of c-myc, cyclin D1, cyclin A, and proliferating cell nuclear antigenTarget of rapamycin (TOR)-signaling and RAIP motifs play distinct roles in the mammalian TOR-dependent phosphorylation of initiation factor 4E-binding protein 1p70(s6k) integrates phosphatidylinositol 3-kinase and rapamycin-regulated signals for E2F regulation in T lymphocytesThe physiology and pathophysiology of rapamycin resistance: implications for cancerNuclear receptor TLX prevents retinal dystrophy and recruits the corepressor atrophin1TOR regulates cell death induced by telomere dysfunction in budding yeast.Down-regulation of long non-coding RNA RP11-708H21.4 is associated with poor prognosis for colorectal cancer and promotes tumorigenesis through regulating AKT/mTOR pathway.Idiopathic pulmonary fibrosis is strongly associated with productive infection by herpesvirus saimiri.Effectiveness and molecular interactions of the clinically active mTORC1 inhibitor everolimus in combination with tamoxifen or letrozole in vitro and in vivo.Inhibitory effects of rapamycin on the different stages of hepatic fibrosisCell cycle regulators: mechanisms and their role in aetiology, prognosis, and treatment of cancer.The target of rapamycin signaling pathway regulates mRNA turnover in the yeast Saccharomyces cerevisiaeDown-regulation of cyclin D1 expression by prostaglandin A(2) is mediated by enhanced cyclin D1 mRNA turnover.Cellular function of p70S6K: a role in regulating cell motility.Cryptotanshinone inhibits cancer cell proliferation by suppressing Mammalian target of rapamycin-mediated cyclin D1 expression and Rb phosphorylation.Temsirolimus in the treatment of relapsed or refractory mantle cell lymphoma.Biological activities of fusarochromanone: a potent anti-cancer agentRapamycin-resistant proliferation of CD8+ T cells correlates with p27kip1 down-regulation and bcl-xL induction, and is prevented by an inhibitor of phosphoinositide 3-kinase activity.The rapamycin-sensitive signal transduction pathway as a target for cancer therapy.Rapamycin inhibits cytoskeleton reorganization and cell motility by suppressing RhoA expression and activity.Expression profile and molecular genetic regulation of cyclin D1 expression in epithelioid sarcoma.Everolimus - a new approach in the treatment of renal cell carcinomaThe mTOR kinase inhibitor rapamycin decreases iNOS mRNA stability in astrocytes.Sirolimus: a comprehensive review.Translational regulation in cell stress and apoptosis. Roles of the eIF4E binding proteins.Calcineurin inhibitors and rapamycin: cancer protection or promotion?2'-AMP and 3'-AMP inhibit proliferation of preglomerular vascular smooth muscle cells and glomerular mesangial cells via A2B receptors2',3'-cAMP, 3'-AMP, and 2'-AMP inhibit human aortic and coronary vascular smooth muscle cell proliferation via A2B receptorsThe role of the ubiquitin/proteasome system in cellular responses to radiation.Deptor knockdown enhances mTOR Activity and protein synthesis in myocytes and ameliorates disuse muscle atrophy.
P2860
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P2860
Rapamycin inhibition of the G1 to S transition is mediated by effects on cyclin D1 mRNA and protein stability.
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
1998年论文
@zh
1998年论文
@zh-cn
name
Rapamycin inhibition of the G1 ...... D1 mRNA and protein stability.
@en
Rapamycin inhibition of the G1 ...... D1 mRNA and protein stability.
@nl
type
label
Rapamycin inhibition of the G1 ...... D1 mRNA and protein stability.
@en
Rapamycin inhibition of the G1 ...... D1 mRNA and protein stability.
@nl
prefLabel
Rapamycin inhibition of the G1 ...... D1 mRNA and protein stability.
@en
Rapamycin inhibition of the G1 ...... D1 mRNA and protein stability.
@nl
P2093
P356
P1476
Rapamycin inhibition of the G1 ...... D1 mRNA and protein stability.
@en
P2093
Hashemolhosseini S
Nagamine Y
P304
14424-14429
P356
10.1074/JBC.273.23.14424
P407
P577
1998-06-01T00:00:00Z