Rap1 mediates sustained MAP kinase activation induced by nerve growth factor.
about
A Rap guanine nucleotide exchange factor enriched highly in the basal gangliaNOEY2 (ARHI), an imprinted putative tumor suppressor gene in ovarian and breast carcinomasCharacterization of GFR, a novel guanine nucleotide exchange factor for Rap1Fibroblast growth factor receptor-1-mediated endothelial cell proliferation is dependent on the Src homology (SH) 2/SH3 domain-containing adaptor protein CrkActivation of the ERK/MAPK pathway by an isoform of rap1GAP associated with G alpha(i)RA-GEF, a novel Rap1A guanine nucleotide exchange factor containing a Ras/Rap1A-associating domain, is conserved between nematode and humansCyclic AMP acts through Rap1 and JNK signaling to increase expression of cutaneous smooth muscle alpha2C-adrenoceptorsRA-GEF-1, a guanine nucleotide exchange factor for Rap1, is activated by translocation induced by association with Rap1*GTP and enhances Rap1-dependent B-Raf activationExendin-4 differentiation of a human pancreatic duct cell line into endocrine cells: involvement of PDX-1 and HNF3beta transcription factorsThe Traf2- and Nck-interacting kinase as a putative effector of Rap2 to regulate actin cytoskeletonDirect binding of p130(Cas) to the guanine nucleotide exchange factor C3GRap1-PDZ-GEF1 interacts with a neurotrophin receptor at late endosomes, leading to sustained activation of Rap1 and ERK and neurite outgrowthDistinct requirements for the Sprouty domain for functional activity of Spred proteinsCritical role for Kalirin in nerve growth factor signaling through TrkA.Meaningful relationships: the regulation of the Ras/Raf/MEK/ERK pathway by protein interactionsR-Ras3/M-Ras induces neuronal differentiation of PC12 cells through cell-type-specific activation of the mitogen-activated protein kinase cascade.Comprehensive mutation analysis of TSC1 and TSC2-and phenotypic correlations in 150 families with tuberous sclerosis.Mechanism of the spatio-temporal regulation of Ras and Rap1.Abl interactor 1 binds to sos and inhibits epidermal growth factor- and v-Abl-induced activation of extracellular signal-regulated kinasesThe strength of interaction at the Raf cysteine-rich domain is a critical determinant of response of Raf to Ras family small GTPasesRit contributes to nerve growth factor-induced neuronal differentiation via activation of B-Raf-extracellular signal-regulated kinase and p38 mitogen-activated protein kinase cascadesA unique pathway for sustained neurotrophin signaling through an ankyrin-rich membrane-spanning proteinCell signaling by receptor tyrosine kinasesGIPC and GAIP form a complex with TrkA: a putative link between G protein and receptor tyrosine kinase pathwaysNeurotrophins: roles in neuronal development and functionThe role of soluble adenylyl cyclase in neurite outgrowthTwo protein tyrosine phosphatases, Ptp2 and Ptp3, modulate the subcellular localization of the Hog1 MAP kinase in yeast.Differential regulation of transcription: repression by unactivated mitogen-activated protein kinase Kss1 requires the Dig1 and Dig2 proteins.Rin GTPase couples nerve growth factor signaling to p38 and b-Raf/ERK pathways to promote neuronal differentiationMultiple roles of Rap1 in hematopoietic cells: complementary versus antagonistic functionsNerve growth factor-dependent activation of the small GTPase RinIdentification and characterization of potential effector molecules of the Ras-related GTPase Rap2The signaling adapter FRS-2 competes with Shc for binding to the nerve growth factor receptor TrkA. A model for discriminating proliferation and differentiationApoptosis signal-regulating kinase 1 (ASK1) induces neuronal differentiation and survival of PC12 cellsDirect binding of the signaling adapter protein Grb2 to the activation loop tyrosines on the nerve growth factor receptor tyrosine kinase, TrkASignaling of hepatocyte growth factor/scatter factor (HGF) to the small GTPase Rap1 via the large docking protein Gab1 and the adapter protein CRKLMAGUIN, a novel neuronal membrane-associated guanylate kinase-interacting proteinFyn and Lck tyrosine kinases regulate tyrosine phosphorylation of p105CasL, a member of the p130Cas docking protein family, in T-cell receptor-mediated signallingThermodynamic and kinetic characterization of the interaction between the Ras binding domain of AF6 and members of the Ras subfamilyThe Csk homologous kinase associates with TrkA receptors and is involved in neurite outgrowth of PC12 cells
P2860
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P2860
Rap1 mediates sustained MAP kinase activation induced by nerve growth factor.
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
1998年论文
@zh
1998年论文
@zh-cn
name
Rap1 mediates sustained MAP kinase activation induced by nerve growth factor.
@en
Rap1 mediates sustained MAP kinase activation induced by nerve growth factor.
@nl
type
label
Rap1 mediates sustained MAP kinase activation induced by nerve growth factor.
@en
Rap1 mediates sustained MAP kinase activation induced by nerve growth factor.
@nl
prefLabel
Rap1 mediates sustained MAP kinase activation induced by nerve growth factor.
@en
Rap1 mediates sustained MAP kinase activation induced by nerve growth factor.
@nl
P2093
P356
P1433
P1476
Rap1 mediates sustained MAP kinase activation induced by nerve growth factor.
@en
P2093
McCleskey EW
P2888
P304
P356
10.1038/33451
P407
P577
1998-04-01T00:00:00Z
P6179
1022890904