Otx2 controls neuron subtype identity in ventral tegmental area and antagonizes vulnerability to MPTP. - Wikidata - awgldk - TriplyDB

Otx2 controls neuron subtype identity in ventral tegmental area and antagonizes vulnerability to MPTP.

Otx2 controls neuron subtype identity in ventral tegmental area and antagonizes vulnerability to MPTP.

http://www.wikidata.org/entity/Q42832693

about

Efficient conversion of astrocytes to functional midbrain dopaminergic neurons using a single polycistronic vector Neuroprotective Transcription Factors in Animal Models of Parkinson Disease Diversity matters - heterogeneity of dopaminergic neurons in the ventral mesencephalon and its relation to Parkinson's Disease Dopaminergic control of autophagic-lysosomal function implicates Lmx1b in Parkinson's disease Genetic dissection of midbrain dopamine neuron development in vivo.Mesodiencephalic dopaminergic neuronal differentiation does not involve GLI2A-mediated SHH-signaling and is under the direct influence of canonical WNT signaling.Embryonic development of selectively vulnerable neurons in Parkinson's disease.Phasic dopamine neuron activity elicits unique mesofrontal plasticity in adolescence Tracing lineages to uncover neuronal identity.Transcription factors Foxa1 and Foxa2 are required for adult dopamine neurons maintenance.Human ESC-derived dopamine neurons show similar preclinical efficacy and potency to fetal neurons when grafted in a rat model of Parkinson's disease.Defining midbrain dopaminergic neuron diversity by single-cell gene expression profiling.Rgs6 is required for adult maintenance of dopaminergic neurons in the ventral substantia nigra.The evolution of dopamine systems in chordates.Midbrain dopamine neurons associated with reward processing innervate the neurogenic subventricular zone.Transcription factors FOXA1 and FOXA2 maintain dopaminergic neuronal properties and control feeding behavior in adult mice.Low Levels of Prohibitin in Substantia Nigra Makes Dopaminergic Neurons Vulnerable in Parkinson's Disease.Excessive Wnt/beta-catenin signaling promotes midbrain floor plate neurogenesis, but results in vacillating dopamine progenitors.Molecular heterogeneity of midbrain dopaminergic neurons--Moving toward single cell resolution.Dynamic temporal requirement of Wnt1 in midbrain dopamine neuron development.Kappa opioid receptors on dopaminergic neurons are necessary for kappa-mediated place aversion Midbrain Gene Screening Identifies a New Mesoaccumbal Glutamatergic Pathway and a Marker for Dopamine Cells Neuroprotected in Parkinson's Disease.Mest/Peg1 Is Essential for the Development and Maintenance of a SNc Neuronal Subset.Survival of a Novel Subset of Midbrain Dopaminergic Neurons Projecting to the Lateral Septum Is Dependent on NeuroD Proteins.Otx genes in neurogenesis of mesencephalic dopaminergic neurons.Cell non-autonomous functions of homeoproteins in neuroprotection in the brain.Engrailed signaling in axon guidance and neuron survival.Cellular programming and reprogramming: sculpting cell fate for the production of dopamine neurons for cell therapy.Molecular mechanisms of dopaminergic subset specification: fundamental aspects and clinical perspectives.Genetic control of midbrain dopaminergic neuron development.Molecular determinants of selective dopaminergic vulnerability in Parkinson's disease: an update.Establishing diversity in the dopaminergic system.Dissecting the role of Engrailed in adult dopaminergic neurons--Insights into Parkinson disease pathogenesis Neuronal Subset-Specific Migration and Axonal Wiring Mechanisms in the Developing Midbrain Dopamine System.Orthodenticle is necessary for survival of a cluster of clonally related dopaminergic neurons in the Drosophila larval and adult brain Time course of dopamine neuron loss and glial response in the 6-OHDA striatal mouse model of Parkinson's disease.Engrailed Homeoprotein Protects Mesencephalic Dopaminergic Neurons from Oxidative Stress Molecular Programming of Mesodiencephalic Dopaminergic Neuronal Subsets.Pitx3 and En1 determine the size and molecular programming of the dopaminergic neuronal pool.A PBX1 transcriptional network controls dopaminergic neuron development and is impaired in Parkinson's disease.

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P2860

Otx2 controls neuron subtype identity in ventral tegmental area and antagonizes vulnerability to MPTP.

http://www.wikidata.org/entity/Q42832693

description

2010 nî lūn-bûn

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2010年の論文

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2010年論文

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name

Otx2 controls neuron subtype i ...... gonizes vulnerability to MPTP.

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Otx2 controls neuron subtype i ...... gonizes vulnerability to MPTP.

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type

label

Otx2 controls neuron subtype i ...... gonizes vulnerability to MPTP.

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Otx2 controls neuron subtype i ...... gonizes vulnerability to MPTP.

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Otx2 controls neuron subtype i ...... gonizes vulnerability to MPTP.

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Otx2 controls neuron subtype i ...... gonizes vulnerability to MPTP.

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Nature Neuroscience

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Otx2 controls neuron subtype i ...... gonizes vulnerability to MPTP.

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P2093

Daniela Omodei

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Dario Acampora

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Luca Giovanni Di Giovannantonio

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Nilima Prakash

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Raffaele Prosperi

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Wolfgang Wurst

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P2860

The foxa2 gene controls the birth and spontaneous degeneration of dopamine neurons in old age

The role of Nurr1 in the development of dopaminergic neurons and Parkinson's disease

Generalized lacZ expression with the ROSA26 Cre reporter strain

Early developmental failure of substantia nigra dopamine neurons in mice lacking the homeodomain gene Pitx3

Otx2 regulates the extent, identity and fate of neuronal progenitor domains in the ventral midbrain

Progressive loss of dopaminergic neurons in the ventral midbrain of adult mice heterozygote for Engrailed1

Differential regulation of midbrain dopaminergic neuron development by Wnt-1, Wnt-3a, and Wnt-5a

Otx dose-dependent integrated control of antero-posterior and dorso-ventral patterning of midbrain

Development of the mesencephalic dopaminergic neuron system is compromised in the absence of neurogenin 2

Nurr1 is essential for the induction of the dopaminergic phenotype and the survival of ventral mesencephalic late dopaminergic precursor neurons

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12

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13

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Antonio Simeone

Michela Di Salvio

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2010-11-07T00:00:00Z

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47701351

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1034281923

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21057506

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