β-catenin tyrosine 654 phosphorylation increases Wnt signalling and intestinal tumorigenesis. - Wikidata - awgldk - TriplyDB

β-catenin tyrosine 654 phosphorylation increases Wnt signalling and intestinal tumorigenesis.

β-catenin tyrosine 654 phosphorylation increases Wnt signalling and intestinal tumorigenesis.

http://www.wikidata.org/entity/Q42860097

about

Wnt/beta-catenin signaling and small molecule inhibitors Epigenetic and Posttranslational Modifications in Light Signal Transduction and the Circadian Clock in Neurospora crassa Is Wilms tumor a candidate neoplasia for treatment with WNT/β-catenin pathway modulators?--A report from the renal tumors biology-driven drug development workshop The many faces and functions of β-catenin Current Understanding on EGFR and Wnt/β-Catenin Signaling in Glioma and Their Possible Crosstalk Inhibition of melanogenesis by the pyridinyl imidazole class of compounds: possible involvement of the Wnt/β-catenin signaling pathway Evolutionary conservation of early mesoderm specification by mechanotransduction in Bilateria A basal gradient of Wnt and stem-cell number influences regional tumour distribution in human and mouse intestinal tracts Dominant β-catenin mutations cause intellectual disability with recognizable syndromic features.Abl regulates planar polarized junctional dynamics through β-catenin tyrosine phosphorylation Bidirectional KCNQ1:β-catenin interaction drives colorectal cancer cell differentiation Downregulated connexin32 promotes EMT through the Wnt/β-catenin pathway by targeting Snail expression in hepatocellular carcinoma.The regulation of β-catenin activity and function in cancer: therapeutic opportunities A positive role of cadherin in Wnt/β-catenin signalling during epithelial-mesenchymal transition.β-catenin signaling in murine liver zonation and regeneration: a Wnt-Wnt situation!E-cadherin phosphorylation occurs during its biosynthesis to promote its cell surface stability and adhesion.Wnt signaling in cancer iNOS activation regulates β-catenin association with its partners in endothelial cells.Integrated β-catenin, BMP, PTEN, and Notch signalling patterns the nephron.α-Catenin phosphorylation promotes intercellular adhesion through a dual-kinase mechanism.Transcriptome analysis of Wnt3a-treated triple-negative breast cancer cells.A conserved phosphorylation switch controls the interaction between cadherin and β-catenin in vitro and in vivo.Nuclear signaling from cadherin adhesion complexes Can we safely target the WNT pathway?Specific armadillo repeat sequences facilitate β-catenin nuclear transport in live cells via direct binding to nucleoporins Nup62, Nup153, and RanBP2/Nup358.Merlin-deficient human tumors show loss of contact inhibition and activation of Wnt/β-catenin signaling linked to the PDGFR/Src and Rac/PAK pathways The BMP pathway either enhances or inhibits the Wnt pathway depending on the SMAD4 and p53 status in CRC.Axin pathway activity regulates in vivo pY654-β-catenin accumulation and pulmonary fibrosis.Wnt/β-Catenin Signaling Activation beyond Robust Nuclear β-Catenin Accumulation in Nondysplastic Barrett's Esophagus: Regulation via Dickkopf-1.VE-cadherin cleavage by ovarian cancer microparticles induces β-catenin phosphorylation in endothelial cells Enhancement of β-catenin activity by BIG1 plus BIG2 via Arf activation and cAMP signals.Phosphorylation of E-cadherin at threonine 790 by protein kinase Cδ reduces β-catenin binding and suppresses the function of E-cadherin.Increasing β-catenin/Wnt3A activity levels drive mechanical strain-induced cell cycle progression through mitosis.β-catenin signaling is required for RAS-driven thyroid cancer through PI3K activation.Synchronization by Daytime Restricted Food Access Modulates the Presence and Subcellular Distribution of β-Catenin and Its Phosphorylated Forms in the Rat Liver.Cancer-associated fibroblasts drive the progression of metastasis through both paracrine and mechanical pressure on cancer tissue.Mechanisms of RAS/β-catenin interactions.Safely targeting cancer stem cells via selective catenin coactivator antagonism.Structural and functional characterization of the α-catenin·β-catenin binding interface in Caenorhabditis elegans reveals conserved requirements for cell-cell adhesion in metazoans.Blocking Wnt Secretion Reduces Growth of Hepatocellular Carcinoma Cell Lines Mostly Independent of β-Catenin Signaling.

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P2860

β-catenin tyrosine 654 phosphorylation increases Wnt signalling and intestinal tumorigenesis.

http://www.wikidata.org/entity/Q42860097

description

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2011年論文

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2011年论文

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2011年论文

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2011年论文

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name

β-catenin tyrosine 654 phospho ...... and intestinal tumorigenesis.

@en

β-catenin tyrosine 654 phospho ...... and intestinal tumorigenesis.

@nl

type

label

β-catenin tyrosine 654 phospho ...... and intestinal tumorigenesis.

@en

β-catenin tyrosine 654 phospho ...... and intestinal tumorigenesis.

@nl

prefLabel

β-catenin tyrosine 654 phospho ...... and intestinal tumorigenesis.

@en

β-catenin tyrosine 654 phospho ...... and intestinal tumorigenesis.

@nl

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GUT.2010.233460

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β-catenin tyrosine 654 phospho ...... and intestinal tumorigenesis.

@en

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Elvira R M Bakker

http://www.w3.org/2001/XMLSchema#string

Frits Meijlink

http://www.w3.org/2001/XMLSchema#string

Lau Blonden

http://www.w3.org/2001/XMLSchema#string

Léon van Gurp

http://www.w3.org/2001/XMLSchema#string

Martin A van der Valk

http://www.w3.org/2001/XMLSchema#string

Myrte Theeuwes

http://www.w3.org/2001/XMLSchema#string

Ngoc H Le

http://www.w3.org/2001/XMLSchema#string

Patrick F Franken

http://www.w3.org/2001/XMLSchema#string

Ron Smits

http://www.w3.org/2001/XMLSchema#string

Wendy van Veelen

http://www.w3.org/2001/XMLSchema#string

P2860

A targeted chain-termination mutation in the mouse Apc gene results in multiple intestinal tumors

Dapper, a Dishevelled-associated antagonist of beta-catenin and JNK signaling, is required for notochord formation

Crystal Structure of a Full-Length β-Catenin

Geldanamycin abrogates ErbB2 association with proteasome-resistant beta-catenin in melanoma cells, increases beta-catenin-E-cadherin association, and decreases beta-catenin-sensitive transcription

Dickkopf1 is required for embryonic head induction and limb morphogenesis in the mouse

Genetic interaction of PGE2 and Wnt signaling regulates developmental specification of stem cells and regeneration

Balancing cell adhesion and Wnt signaling, the key role of beta-catenin

Genetic dissection of differential signaling threshold requirements for the Wnt/beta-catenin pathway in vivo

Expression of CD44 in Apc and Tcf mutant mice implies regulation by the WNT pathway

Tumorigenesis in the multiple intestinal neoplasia mouse: redundancy of negative regulators and specificity of modifiers

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10.1136/GUT.2010.233460

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9

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60

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Ernst J Kuipers

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2011-02-09T00:00:00Z

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49822923

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21307168

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phosphorylation

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3152867

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