Human leukocyte elastase is an endogenous ligand for the integrin CR3 (CD11b/CD18, Mac-1, alpha M beta 2) and modulates polymorphonuclear leukocyte adhesion. - Wikidata - awgldk - TriplyDB

Human leukocyte elastase is an endogenous ligand for the integrin CR3 (CD11b/CD18, Mac-1, alpha M beta 2) and modulates polymorphonuclear leukocyte adhesion.

Human leukocyte elastase is an endogenous ligand for the integrin CR3 (CD11b/CD18, Mac-1, alpha M beta 2) and modulates polymorphonuclear leukocyte adhesion.

http://www.wikidata.org/entity/Q42943798

about

JAM-C is a component of desmosomes and a ligand for CD11b/CD18-mediated neutrophil transepithelial migration Neutrophil primary granule proteins HBP and HNP1-3 boost bacterial phagocytosis by human and murine macrophages Leukocyte integrins: role in leukocyte recruitment and as therapeutic targets in inflammatory disease Regulation of CD18 expression on neutrophils in response to fluid shear stress α1Proteinase inhibitor regulates CD4+ lymphocyte levels and is rate limiting in HIV-1 disease Cleavage of the CD11b extracellular domain by the leukocyte serprocidins is critical for neutrophil detachment during chemotaxis.Identification of a negatively charged peptide motif within the catalytic domain of progelatinases that mediates binding to leukocyte beta 2 integrins.Integrins as "functional hubs" in the regulation of pathological angiogenesis The alphaMbeta2 integrin and its role in neutrophil function.Leukocyte proteinases in wound healing: roles in physiologic and pathologic processes.Proteolysis of monocyte CD14 by human leukocyte elastase inhibits lipopolysaccharide-mediated cell activation Alpha1-antitrypsin monotherapy prolongs islet allograft survival in mice.Enzymatic activities of bovine peripheral blood leukocytes and milk polymorphonuclear neutrophils during intramammary inflammation caused by lipopolysaccharide.Leukocyte elastase: physiological functions and role in acute lung injury.Ligand recognition specificity of leukocyte integrin αMβ2 (Mac-1, CD11b/CD18) and its functional consequences.The opioid peptide dynorphin A induces leukocyte responses via integrin Mac-1 (αMβ2, CD11b/CD18).Leukocyte cell surface proteinases: regulation of expression, functions, and mechanisms of surface localization.Neutrophil serine proteases fine-tune the inflammatory response Small GTPases and LFA-1 reciprocally modulate adhesion and signaling.The heparan sulfate proteoglycan form of epithelial CD44v3 serves as a CD11b/CD18 counter-receptor during polymorphonuclear leukocyte transepithelial migration.Influence of parasite encoded inhibitors of serine peptidases in early infection of macrophages with Leishmania major Transepithelial migration of neutrophils: mechanisms and implications for acute lung injury Neutrophil-derived azurocidin alarms the immune system.Mechanisms of immune complex-mediated neutrophil recruitment and tissue injury.Neutrophils: game changers in glomerulonephritis?Antagonist-induced deadhesion of specifically adhered vesicles.Epithelial adhesion molecules and the regulation of intestinal homeostasis during neutrophil transepithelial migration.Pathobiology of neutrophil-epithelial interactions.Neutrophil elastase is needed for neutrophil emigration into lungs in ventilator-induced lung injury Dipeptidyl peptidase I activates neutrophil-derived serine proteases and regulates the development of acute experimental arthritis.Bordetella pertussis adenylate cyclase toxin (ACT) induces cyclooxygenase-2 (COX-2) in murine macrophages and is facilitated by ACT interaction with CD11b/CD18 (Mac-1).Aberrant subcellular targeting of the G185R neutrophil elastase mutant associated with severe congenital neutropenia induces premature apoptosis of differentiating promyelocytes.Association of BAP31 with CD11b/CD18. Potential role in intracellular trafficking of CD11b/CD18 in neutrophils.A molecular basis for integrin alphaMbeta 2 ligand binding promiscuity.Size-fractionated heparins have differential effects on human neutrophil function in vitro.Leukotriene B4-Neutrophil Elastase Axis Drives Neutrophil Reverse Transendothelial Cell Migration In Vivo.Pharmacological activities of TEI-8362, a novel inhibitor of human neutrophil elastase.Leishmania inhibitor of serine peptidase 2 prevents TLR4 activation by neutrophil elastase promoting parasite survival in murine macrophages.Regulation of apoptosis and priming of neutrophil oxidative burst by diisopropyl fluorophosphate.Fibrinogen is degraded and internalized during incubation with neutrophils, and fibrinogen products localize to electron lucent vesicles.

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Human leukocyte elastase is an endogenous ligand for the integrin CR3 (CD11b/CD18, Mac-1, alpha M beta 2) and modulates polymorphonuclear leukocyte adhesion.

http://www.wikidata.org/entity/Q42943798

description

1996 nî lūn-bûn

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Human leukocyte elastase is an ...... phonuclear leukocyte adhesion.

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P2860

T-cell receptor cross-linking transiently stimulates adhesiveness through LFA-1

Down-regulation of a serine protease, myeloblastin, causes growth arrest and differentiation of promyelocytic leukemia cells

ADAM, a novel family of membrane proteins containing A Disintegrin And Metalloprotease domain: multipotential functions in cell-cell and cell-matrix interactions

Cell surface-bound elastase and cathepsin G on human neutrophils: a novel, non-oxidative mechanism by which neutrophils focus and preserve catalytic activity of serine proteinases

Amino acid sequence of CAP37, a human neutrophil granule-derived antibacterial and monocyte-specific chemotactic glycoprotein structurally similar to neutrophil elastase

Elastase and cathepsin G of human monocytes. Quantification of cellular content, release in response to stimuli, and heterogeneity in elastase-mediated proteolytic activity

Complementary DNA sequence of human neutrophil azurocidin, an antibiotic with extensive homology to serine proteases

Isolation, characterization, and amino-terminal amino acid sequence analysis of human neutrophil cathepsin G from normal donors

Adhesive receptor Mac-1 coordinates the activation of factor X on stimulated cells of monocytic and myeloid differentiation: an alternative initiation of the coagulation protease cascade.

Complement receptor type three (CD11b/CD18) of human polymorphonuclear leukocytes recognizes fibrinogen.

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