Pacidamycin biosynthesis: identification and heterologous expression of the first uridyl peptide antibiotic gene cluster.
about
Biosynthesis of the tunicamycin antibiotics proceeds via unique exo-glycal intermediatesRevealing the first uridyl peptide antibiotic biosynthetic gene cluster and probing pacidamycin biosynthesisIdentification of the biosynthetic gene cluster for the pacidamycin group of peptidyl nucleoside antibiotics.Characterization of the amicetin biosynthesis gene cluster from Streptomyces vinaceusdrappus NRRL 2363 implicates two alternative strategies for amide bond formation.Characterization of LipL as a non-heme, Fe(II)-dependent α-ketoglutarate:UMP dioxygenase that generates uridine-5'-aldehyde during A-90289 biosynthesis.Characterization of biosynthetic genes of ascamycin/dealanylascamycin featuring a 5'-O-sulfonamide moiety in Streptomyces sp. JCM9888.tRNA-dependent peptide bond formation by the transferase PacB in biosynthesis of the pacidamycin group of pentapeptidyl nucleoside antibiotics.Biosynthetic origin and mechanism of formation of the aminoribosyl moiety of peptidyl nucleoside antibiotics.Identification of novel mureidomycin analogues via rational activation of a cryptic gene cluster in Streptomyces roseosporus NRRL 15998.Biosynthesis of albomycin δ(2) provides a template for assembling siderophore and aminoacyl-tRNA synthetase inhibitor conjugates.Streptomyces lividans blasticidin S deaminase and its application in engineering a blasticidin S-producing strain for ease of genetic manipulationSsaA, a member of a novel class of transcriptional regulators, controls sansanmycin production in Streptomyces sp. strain SS through a feedback mechanism.Improving the N-terminal diversity of sansanmycin through mutasynthesis.Pleiotropic regulatory genes bldA, adpA and absB are implicated in production of phosphoglycolipid antibiotic moenomycin.Sansanmycin natural product analogues as potent and selective anti-mycobacterials that inhibit lipid I biosynthesis.The regulation and biosynthesis of antimycinsBiosynthesis of natural products containing β-amino acids.Natural and engineered biosynthesis of nucleoside antibiotics in Actinomycetes.Prospecting for new bacterial metabolites: a glossary of approaches for inducing, activating and upregulating the biosynthesis of bacterial cryptic or silent natural products.Nature's combinatorial biosynthesis and recently engineered production of nucleoside antibiotics in Streptomyces.Chemical logic and enzymatic machinery for biological assembly of peptidyl nucleoside antibioticsLiving GenoChemetics by hyphenating synthetic biology and synthetic chemistry in vivoCrystallization and preliminary X-ray analysis of Pac17 from the pacidamycin-biosynthetic cluster of Streptomyces coeruleorubidus.Mechanism of action of the uridyl peptide antibiotics: an unexpected link to a protein-protein interaction site in translocase MraY.Nine enzymes are required for assembly of the pacidamycin group of peptidyl nucleoside antibioticsIdentification of mureidomycin analogues and functional analysis of an N-acetyltransferase in napsamycin biosynthesis.Identification of the gene cluster involved in muraymycin biosynthesis from Streptomyces sp. NRRL 30471.Pac13 is a Small, Monomeric Dehydratase that Mediates the Formation of the 3'-Deoxy Nucleoside of Pacidamycins.MbtH homology codes to identify gifted microbes for genome mining.Exploiting the genome sequence of Streptomyces nodosus for enhanced antibiotic production.Synthetic Biology of Antibiotic Production
P2860
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P2860
Pacidamycin biosynthesis: identification and heterologous expression of the first uridyl peptide antibiotic gene cluster.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
2010年论文
@zh
2010年论文
@zh-cn
name
Pacidamycin biosynthesis: iden ...... ptide antibiotic gene cluster.
@en
Pacidamycin biosynthesis: iden ...... ptide antibiotic gene cluster.
@nl
type
label
Pacidamycin biosynthesis: iden ...... ptide antibiotic gene cluster.
@en
Pacidamycin biosynthesis: iden ...... ptide antibiotic gene cluster.
@nl
prefLabel
Pacidamycin biosynthesis: iden ...... ptide antibiotic gene cluster.
@en
Pacidamycin biosynthesis: iden ...... ptide antibiotic gene cluster.
@nl
P2093
P50
P356
P1433
P1476
Pacidamycin biosynthesis: iden ...... ptide antibiotic gene cluster.
@en
P2093
Emma J Rackham
Rebecca J M Goss
Sabine Grüschow
Shilo Dickens
P304
P356
10.1002/CBIC.201000200
P577
2010-08-01T00:00:00Z