A simple method for measuring the relative force exerted by myosin on actin filaments in the in vitro motility assay: evidence that tropomyosin and troponin increase force in single thin filaments.
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Ensemble force changes that result from human cardiac myosin mutations and a small-molecule effectorMolecular mechanical differences between isoforms of contractile actin in the presence of isoforms of smooth muscle tropomyosinA subdomain interaction at the base of the lever allosterically tunes the mechanochemical mechanism of myosin 5aThe molecular effects of skeletal muscle myosin regulatory light chain phosphorylation.A single-headed fission yeast myosin V transports actin in a tropomyosin-dependent mannerThe molecular basis of frictional loads in the in vitro motility assay with applications to the study of the loaded mechanochemistry of molecular motors.The direct molecular effects of fatigue and myosin regulatory light chain phosphorylation on the actomyosin contractile apparatus.Hypertrophic cardiomyopathy associated Lys104Glu mutation in the myosin regulatory light chain causes diastolic disturbance in miceElementary steps of the cross-bridge cycle in bovine myocardium with and without regulatory proteins.Elementary steps of the cross-bridge cycle in fast-twitch fiber types from rabbit skeletal muscles.Future challenges in single-molecule fluorescence and laser trap approaches to studies of molecular motors.A hearing loss-associated myo1c mutation (R156W) decreases the myosin duty ratio and force sensitivity.Use of thin filament reconstituted muscle fibres to probe the mechanism of force generation.Functional effects of nemaline myopathy mutations on human skeletal alpha-actin.Molecular consequences of the R453C hypertrophic cardiomyopathy mutation on human β-cardiac myosin motor function.Regulatory light chain mutations associated with cardiomyopathy affect myosin mechanics and kineticsRemoval of the cardiac myosin regulatory light chain increases isometric force productionHypertrophic and dilated cardiomyopathy: four decades of basic research on muscle lead to potential therapeutic approaches to these devastating genetic diseases.A study of tropomyosin's role in cardiac function and disease using thin-filament reconstituted myocardium.Actomyosin based contraction: one mechanokinetic model from single molecules to muscle?The role of tropomyosin domains in cooperative activation of the actin-myosin interaction.Force-generating capacity of human myosin isoforms extracted from single muscle fibre segments.Hypothesis and theory: mechanical instabilities and non-uniformities in hereditary sarcomere myopathies.Tropomyosin period 3 is essential for enhancement of isometric tension in thin filament-reconstituted bovine myocardium.Effects of tropomyosin internal deletion Delta23Tm on isometric tension and the cross-bridge kinetics in bovine myocardium.The effect of tropomyosin on force and elementary steps of the cross-bridge cycle in reconstituted bovine myocardium.A mixed-kinetic model describes unloaded velocities of smooth, skeletal, and cardiac muscle myosin filaments in vitro.Robust mechanobiological behavior emerges in heterogeneous myosin systems.Temperature change does not affect force between regulated actin filaments and heavy meromyosin in single-molecule experiments.The effect of mutations in alpha-tropomyosin (E40K and E54K) that cause familial dilated cardiomyopathy on the regulatory mechanism of cardiac muscle thin filaments.
P2860
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P2860
A simple method for measuring the relative force exerted by myosin on actin filaments in the in vitro motility assay: evidence that tropomyosin and troponin increase force in single thin filaments.
description
2000 nî lūn-bûn
@nan
2000年の論文
@ja
2000年学术文章
@wuu
2000年学术文章
@zh
2000年学术文章
@zh-cn
2000年学术文章
@zh-hans
2000年学术文章
@zh-my
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@zh-hant
name
A simple method for measuring ...... orce in single thin filaments.
@en
A simple method for measuring ...... orce in single thin filaments.
@nl
type
label
A simple method for measuring ...... orce in single thin filaments.
@en
A simple method for measuring ...... orce in single thin filaments.
@nl
prefLabel
A simple method for measuring ...... orce in single thin filaments.
@en
A simple method for measuring ...... orce in single thin filaments.
@nl
P2093
P2860
P1433
P1476
A simple method for measuring ...... orce in single thin filaments.
@en
P2093
P2860
P304
P356
10.1042/0264-6021:3500693
P407
P478
P577
2000-09-01T00:00:00Z