Modulation of the hepatitis C virus RNA-dependent RNA polymerase activity by the non-structural (NS) 3 helicase and the NS4B membrane protein.
about
Protein kinase C-related kinase 2 regulates hepatitis C virus RNA polymerase function by phosphorylationRNA helicases at work: binding and rearrangingDocking studies of Pakistani HCV NS3 helicase: a possible antiviral drug targetCharacterization of Nonstructural Protein Membrane Anchor Deletion Mutants Expressed in the Context of the Hepatitis C Virus PolyproteinStimulation of hepatitis C virus (HCV) nonstructural protein 3 (NS3) helicase activity by the NS3 protease domain and by HCV RNA-dependent RNA polymeraseA novel, highly selective inhibitor of pestivirus replication that targets the viral RNA-dependent RNA polymerase.Hepatitis C virus subgenomic replicon requires an active NS3 RNA helicase.Effect of hepatitis C virus (HCV) NS5B-nucleolin interaction on HCV replication with HCV subgenomic replicon.Protein-Protein Interactions between Hepatitis C Virus Nonstructural ProteinsRole of Divalent Metal Cations in ATP Hydrolysis Catalyzed by the Hepatitis C Virus NS3 Helicase: Magnesium Provides a Bridge for ATP to Fuel UnwindingIdentification of Determinants Involved in Initiation of Hepatitis C Virus RNA Synthesis by Using Intergenotypic Replicase ChimerasAllelic Variation in the Hepatitis C Virus NS4B Protein Dramatically Influences RNA ReplicationThe NS3 Helicase and NS5B-to-3'X Regions Are Important for Efficient Hepatitis C Virus Strain JFH-1 Replication in Huh7 CellsEffects of Mutagenic and Chain-Terminating Nucleotide Analogs on Enzymes Isolated from Hepatitis C Virus Strains of Various GenotypesHepatitis C virus NS3 helicase forms oligomeric structures that exhibit optimal DNA unwinding activity in vitroA Genetic Interaction between Hepatitis C Virus NS4B and NS3 Is Important for RNA ReplicationNS3 Helicase from the Hepatitis C Virus Can Function as a Monomer or Oligomer Depending on Enzyme and Substrate ConcentrationsThe Hepatitis C Virus NS4B Protein Can trans-Complement Viral RNA Replication and Modulates Production of Infectious VirusHepatitis C Virus NS5B Polymerase Exhibits Distinct Nucleotide Requirements for Initiation and ElongationThe Hepatitis C Virus NS5A Stimulates NS5B During In Vitro RNA Synthesis in a Template Specific MannerHelicase inhibitors as specifically targeted antiviral therapy for hepatitis CBluetongue virus: dissection of the polymerase complexBovine viral diarrhea virus NS4B protein is an integral membrane protein associated with Golgi markers and rearranged host membranesMutations in Classical Swine Fever Virus NS4B Affect Virulence in SwineThe RNA helicase Mtr4p modulates polyadenylation in the TRAMP complex.Comparative Proteomics Reveals Important Viral-Host Interactions in HCV-Infected Human Liver CellsInitiation of RNA synthesis by the hepatitis C virus RNA-dependent RNA polymerase is affected by the structure of the RNA template.Identification of PTC725, an orally bioavailable small molecule that selectively targets the hepatitis C Virus NS4B proteinSingle-molecule studies reveal that DEAD box protein DDX1 promotes oligomerization of HIV-1 Rev on the Rev response element.Inhibition of hepatitis C virus replication by single-stranded RNA structural mimics.Regulation of de novo-initiated RNA synthesis in hepatitis C virus RNA-dependent RNA polymerase by intermolecular interactions.RNA helicases: emerging roles in viral replication and the host innate response.RNA helicases in infection and disease.The hepatitis C virus core protein can modulate RNA-dependent RNA synthesis by the 2a polymerase.The hepatitis C virus NS3 protein: a model RNA helicase and potential drug targetCharged residues in hepatitis C virus NS4B are critical for multiple NS4B functions in RNA replication.Identification of AP80978, a novel small-molecule inhibitor of hepatitis C virus replication that targets NS4B.Nonstructural protein 5A (NS5A) and human replication protein A increase the processivity of hepatitis C virus NS5B polymerase activity in vitro.Inhibition of protease-inhibitor-resistant hepatitis C virus replicons and infectious virus by intracellular intrabodies.Encoded library technology screening of hepatitis C virus NS4B yields a small-molecule compound series with in vitro replicon activity.
P2860
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P2860
Modulation of the hepatitis C virus RNA-dependent RNA polymerase activity by the non-structural (NS) 3 helicase and the NS4B membrane protein.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年学术文章
@wuu
2002年学术文章
@zh
2002年学术文章
@zh-cn
2002年学术文章
@zh-hans
2002年学术文章
@zh-my
2002年学术文章
@zh-sg
2002年學術文章
@yue
2002年學術文章
@zh-hant
name
Modulation of the hepatitis C ...... and the NS4B membrane protein.
@en
Modulation of the hepatitis C ...... activity by the non-structural
@nl
type
label
Modulation of the hepatitis C ...... and the NS4B membrane protein.
@en
Modulation of the hepatitis C ...... activity by the non-structural
@nl
prefLabel
Modulation of the hepatitis C ...... and the NS4B membrane protein.
@en
Modulation of the hepatitis C ...... activity by the non-structural
@nl
P2093
P2860
P356
P1476
Modulation of the hepatitis C ...... and the NS4B membrane protein
@en
P2093
Bhuvanesh Dave
John E G McCarthy
Kevin D Raney
Maria Nardelli
Sabina Piccininni
P2860
P304
45670-45679
P356
10.1074/JBC.M204124200
P407
P577
2002-09-15T00:00:00Z