A chemical screening approach reveals that indole fluorescence is quenched by pre-fibrillar but not fibrillar amyloid-beta.
about
Dye-binding assays for evaluation of the effects of small molecule inhibitors on amyloid (aβ) self-assemblyQuantifying prefibrillar amyloids in vitro by using a "thioflavin-like" spectroscopic method.Dihydroxybenzoic acid isomers differentially dissociate soluble biotinyl-Aβ(1-42) oligomers.Insight into amyloid structure using chemical probes.Reactivity of diphenylpropynone derivatives toward metal-associated amyloid-β species.Biochemistry of amyloid β-protein and amyloid deposits in Alzheimer disease.Compounds for imaging amyloid-β deposits in an Alzheimer's brain: a patent review.The molecular mechanism for human metallothionein-3 to protect against the neuronal cytotoxicity of Aβ(1-42) with Cu ions.Development of bifunctional stilbene derivatives for targeting and modulating metal-amyloid-β species.Small molecule modulators of copper-induced Abeta aggregationBifunctional compounds for controlling metal-mediated aggregation of the aβ42 peptide.The neurotransmitter serotonin interrupts α-synuclein amyloid maturation.Probing the molecular mechanism of cerium oxide nanoparticles in protecting against the neuronal cytotoxicity of Aβ1-42 with copper ions.Zinc ion rapidly induces toxic, off-pathway amyloid-β oligomers distinct from amyloid-β derived diffusible ligands in Alzheimer's disease.
P2860
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P2860
A chemical screening approach reveals that indole fluorescence is quenched by pre-fibrillar but not fibrillar amyloid-beta.
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年学术文章
@wuu
2009年学术文章
@zh
2009年学术文章
@zh-cn
2009年学术文章
@zh-hans
2009年学术文章
@zh-my
2009年学术文章
@zh-sg
2009年學術文章
@yue
2009年學術文章
@zh-hant
name
A chemical screening approach ...... ut not fibrillar amyloid-beta.
@en
A chemical screening approach ...... ut not fibrillar amyloid-beta.
@nl
type
label
A chemical screening approach ...... ut not fibrillar amyloid-beta.
@en
A chemical screening approach ...... ut not fibrillar amyloid-beta.
@nl
prefLabel
A chemical screening approach ...... ut not fibrillar amyloid-beta.
@en
A chemical screening approach ...... ut not fibrillar amyloid-beta.
@nl
P2093
P2860
P1476
A chemical screening approach ...... ut not fibrillar amyloid-beta.
@en
P2093
Ashley A Reinke
Han Yiau Seh
Jason E Gestwicki
P2860
P304
P356
10.1016/J.BMCL.2009.07.082
P407
P577
2009-07-19T00:00:00Z