about
The discovery of capsazepine, the first competitive antagonist of the sensory neuron excitants capsaicin and resiniferatoxinA novel small conductance Ca2+-activated K+ channel blocker from Oxyuranus scutellatus taipan venom. Re-evaluation of taicatoxin as a selective Ca2+ channel probeModes of hexamethonium action on acetylcholine receptor channels in frog skeletal muscleANKTM1, a TRP-like channel expressed in nociceptive neurons, is activated by cold temperaturesA TRP channel that senses cold stimuli and mentholA heat-sensitive TRP channel expressed in keratinocytesMethylglyoxal evokes pain by stimulating TRPA1Monoacylglycerols activate TRPV1--a link between phospholipase C and TRPV1Inhibition of spinal microglial cathepsin S for the reversal of neuropathic painTRPM8 is a neuronal osmosensor that regulates eye blinking in mice.Evidence for the pathophysiological relevance of TRPA1 receptors in the cardiovascular system in vivo.4-oxo-2-nonenal (4-ONE): evidence of transient receptor potential ankyrin 1-dependent and -independent nociceptive and vasoactive responses in vivo.TRPA1 mediates spinal antinociception induced by acetaminophen and the cannabinoid Δ(9)-tetrahydrocannabiorcol.TRPM8 activation by menthol, icilin, and cold is differentially modulated by intracellular pH.TRPA1 has a key role in the somatic pro-nociceptive actions of hydrogen sulfideModifications of gait as predictors of natural osteoarthritis progression in STR/Ort miceAntihyperalgesic activity of a novel nonpeptide bradykinin B1 receptor antagonist in transgenic mice expressing the human B1 receptorStreptozotocin Stimulates the Ion Channel TRPA1 Directly: INVOLVEMENT OF PEROXYNITRITEEnvironmental cold exposure increases blood flow and affects pain sensitivity in the knee joints of CFA-induced arthritic mice in a TRPA1-dependent manner.TRPA1 mediates the hypothermic action of acetaminophen.TRPA1 activation leads to neurogenic vasodilatation: involvement of reactive oxygen nitrogen species in addition to CGRP and NOTherapeutic potential of cannabinoid receptor agonists as analgesic agents.Selective internalization of sodium channels in rat dorsal root ganglion neurons infected with herpes simplex virus-1Nociceptive Sensitizers Are Regulated in Damaged Joint Tissues, Including Articular Cartilage, When Osteoarthritic Mice Display Pain Behavior.Clioquinol and pyrithione activate TRPA1 by increasing intracellular Zn2+.Transient receptor potential A1 is a sensory receptor for multiple products of oxidative stress.Modulation of the cold-activated channel TRPM8 by lysophospholipids and polyunsaturated fatty acidsMonocytes expressing CX3CR1 orchestrate the development of vincristine-induced pain.Peripheral nerve injury induces cannabinoid receptor 2 protein expression in rat sensory neurons.Activation of transient receptor potential ankyrin 1 induces CGRP release from spinal cord synaptosomes.Stimulation of GLP-1 secretion downstream of the ligand-gated ion channel TRPA1.Regulation of calcitonin gene-related peptide and TRPV1 in a rat model of osteoarthritis.Cannabinoid 1 receptors are expressed in nociceptive primary sensory neurons.Cannabinoid 1 receptors are expressed by nerve growth factor- and glial cell-derived neurotrophic factor-responsive primary sensory neurones.Anti-hyperalgesic activity of the cox-2 inhibitor lumiracoxib in a model of bone cancer pain in the rat.7-tert-Butyl-6-(4-chloro-phenyl)-2-thioxo-2,3-dihydro-1H-pyrido[2,3-d]pyrimidin-4-one, a classic polymodal inhibitor of transient receptor potential vanilloid type 1 with a reduced liability for hyperthermia, is analgesic and ameliorates visceral hyG protein βγ subunits inhibit TRPM3 ion channels in sensory neurons.The roles of iPLA2, TRPM8 and TRPA1 in chemically induced cold hypersensitivity.TRPA1 is essential for the vascular response to environmental cold exposure.Metabotropic glutamate receptor 5 upregulation in A-fibers after spinal nerve injury: 2-methyl-6-(phenylethynyl)-pyridine (MPEP) reverses the induced thermal hyperalgesia.
P50
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P50
description
hulumtues
@sq
researcher
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wetenschapper
@nl
հետազոտող
@hy
name
Stuart Bevan
@ast
Stuart Bevan
@en
Stuart Bevan
@es
Stuart Bevan
@nl
Stuart Bevan
@sl
type
label
Stuart Bevan
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Stuart Bevan
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Stuart Bevan
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Stuart Bevan
@nl
Stuart Bevan
@sl
prefLabel
Stuart Bevan
@ast
Stuart Bevan
@en
Stuart Bevan
@es
Stuart Bevan
@nl
Stuart Bevan
@sl
P106
P1153
7005746396
P21
P31
P496
0000-0002-8977-1797