Proteinase activity and receptor cleavage: mechanism for insulin resistance in the spontaneously hypertensive rat.
about
Protease activity increases in plasma, peritoneal fluid, and vital organs after hemorrhagic shock in ratsNovel 19F activatable probe for the detection of matrix metalloprotease-2 activity by MRI/MRS.Regulation and involvement of matrix metalloproteinases in vascular diseasesMetalloproteinases: key and common mediators of multiple GPCRs and candidate therapeutic targets in models of hypertensive cardiac disease.Molecular Signals Elicited by GPCR Agonists in Hypertension, Cardiovascular Remodeling: Are MMPs and ADAMs Elusive Therapeutic Targets?Matrix metalloproteinases: discrete elevations in essential hypertension and hypertensive end-stage renal disease.Matrix metalloproteinases cleave the beta2-adrenergic receptor in spontaneously hypertensive rats.Receptor cleavage reduces the fluid shear response in neutrophils of the spontaneously hypertensive ratAcute venous occlusion enhances matrix metalloprotease activity: Implications on endothelial dysfunctionRelative roles of doxycycline and cation chelation in endothelial glycan shedding and adhesion of leukocytes.Detection of protease activities by flash chronopotentiometry using a reversible polycation-sensitive polymeric membrane electrode.Protease Activity and the Role of the Endothelial Glycocalyx in Inflammation.Honey supplementation in spontaneously hypertensive rats elicits antihypertensive effect via amelioration of renal oxidative stressInhibition of matrix metalloproteinase-2 improves endothelial function and prevents hypertension in insulin-resistant rats.Proteolytic Activity Attenuates the Response of Endothelial Cells to Fluid Shear StressReceptor cleavage and P-selectin-dependent reduction of leukocyte adhesion in the spontaneously hypertensive rat.Emergence of a metalloproteinase / phospholipase A2 axis of systemic inflammation.Cleavage and reduced CD36 ectodomain density on heart and spleen macrophages in the spontaneously hypertensive rat.Proof of Concept: Matrix metalloproteinase inhibitor decreases inflammation and improves muscle insulin sensitivity in people with type 2 diabetesProteolytic receptor cleavage in the pathogenesis of blood rheology and co-morbidities in metabolic syndrome. Early forms of autodigestion.The autodigestion hypothesis for shock and multi-organ failure.The endothelial glycocalyx as a barrier to leukocyte adhesion and its mediation by extracellular proteases.An emerging role of degrading proteinases in hypertension and the metabolic syndrome: autodigestion and receptor cleavage.Matrix metalloproteinases and small artery remodeling.Insights into the activity, differential expression, mutual regulation, and functions of matrix metalloproteinases and a disintegrin and metalloproteinases in hypertension and cardiac disease.Matrix metalloproteinases are involved in cardiovascular diseases.Neutrophil proteolytic activation cascades: a possible mechanistic link between chronic periodontitis and coronary heart disease.THE AUTODIGESTION HYPOTHESIS AND RECEPTOR CLEAVAGE IN DIABETES AND HYPERTENSION.Angiogenesis and Proteinases: Influence on Vascular Morphogenesis, Stabilization and Regression.The autodigestion hypothesis: Proteolytic receptor cleavage in rheological and cardiovascular cell dysfunction1.A New Hypothesis for Insulin Resistance in Hypertension Due to Receptor Cleavage.The oxygen free radicals control MMP-9 and transcription factors expression in the spontaneously hypertensive rat.Enhanced matrix metalloproteinase activity in the spontaneously hypertensive rat: VEGFR-2 cleavage, endothelial apoptosis, and capillary rarefactionNuclear factor kappa B and matrix metalloproteinase induced receptor cleavage in the spontaneously hypertensive rat.Proteolytic Cleavage of the Red Blood Cell Glycocalyx in a Genetic Form of Hypertension.Pancreatic digestive enzyme blockade in the small intestine prevents insulin resistance in hemorrhagic shock.Matrix metalloproteinase activity causes VEGFR-2 cleavage and microvascular rarefaction in rat mesentery.Association of MMP-8 with obesity, smoking and insulin resistance.Constitutive expression and enzymatic cleavage of ICAM-1 in the spontaneously hypertensive rat.Vascular receptors as new substrates for matrix metalloproteinases in hypertension and other inflammatory states.
P2860
Q28730902-AB809BA3-64D9-448B-ADED-EB2D55144708Q30856771-CA964112-F61C-4407-8F79-E2BFC1673F38Q33773304-268A83DB-AB36-43B8-8E13-399A91780F7CQ33807027-D24F956C-643F-4826-BCC6-E6E553704FC0Q33807091-9B9F3A7B-B58E-4272-A833-AF1D6E19B242Q33872836-B6666055-D827-46E3-AB06-D29080010B97Q33994864-36C29CE3-A51D-4B8C-AB81-BF4E4C10560BQ34426368-F8428DA6-918A-40AE-B8D1-013483E678DEQ34491348-DD7533E1-3DA1-4271-A261-DB9AB1DF4A98Q34600385-EEC1E386-5396-4AED-A5E0-8EDD7F44BC1DQ35074826-EC178E36-0571-4849-9981-C4323AD76D35Q35503145-2506AD3E-FAAB-4A4D-B519-F270D0AB9D34Q35725463-3114B691-18FE-4485-B789-955BD03E8FB7Q35859780-D4A51082-483A-43AD-9048-0EA1D21DE418Q35915595-CF9CD1BB-8448-40E1-A213-FC90A51E0A42Q36056004-20FE8AA5-87B9-4265-BAA2-190A16DCBF18Q36176901-9D706614-E5A8-4519-AB71-D8E94EAE65ACQ36274816-B0C04B8B-803C-44FC-B658-639BDD5704C2Q36427429-FB900D50-975B-4CE5-AAF3-460128A9E9FBQ37228621-ED79E927-F2F1-4CA3-9B3B-C2AD87D9F47DQ37620034-BB1E6AAD-2B72-499B-AE04-E40BD7032FBCQ37943787-155EC20B-DF89-4098-B91E-25675D5D31F4Q37955866-A6F3BECE-5A49-42CC-AC6E-08E78C136808Q37962503-289B7CE8-D0C7-45E2-BB66-BBCE9AA42217Q38061567-08EA245C-F8D2-49F1-BCC3-369DEC233EA8Q38224193-D381A95F-171C-4BF1-BA37-FA06F9D20C7FQ38648056-75E9DE69-D083-406E-A2D1-B6F70EDB8E21Q39012642-2F315DAF-5283-46D9-956D-E98516E512D7Q39367074-F3CAD747-3086-4B6E-9188-A6ACCAE43960Q40304817-D30C9162-1B05-447C-9E65-F2E0A642EA22Q41343627-399596D8-EBA5-440B-8AD3-89ABE640EE8BQ41808888-443B5A95-5921-427E-81B4-BEF7677BCB20Q41817544-BE7DD4AD-9826-4759-B21D-F7E2899C04FCQ41821185-72A2EB9C-B76C-48CB-BE9F-4EE78A34C616Q41837752-79F06E66-F055-4C97-A35B-FE3DB59FD1FDQ41858386-5D752E50-418F-489F-B9B0-6533EC6F3290Q41885523-64B2359C-2688-4073-B12B-C0D36682F532Q42103591-9553D74F-E7D6-4CC0-AEFA-4A57230FD33FQ42720460-DE303491-3CE5-4B65-A67A-C1440D84B3E2Q42733133-BF2A5238-D1DD-4DA1-84A3-7476629EE695
P2860
Proteinase activity and receptor cleavage: mechanism for insulin resistance in the spontaneously hypertensive rat.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
@zh-hant
name
Proteinase activity and recept ...... pontaneously hypertensive rat.
@en
Proteinase activity and recept ...... pontaneously hypertensive rat.
@nl
type
label
Proteinase activity and recept ...... pontaneously hypertensive rat.
@en
Proteinase activity and recept ...... pontaneously hypertensive rat.
@nl
prefLabel
Proteinase activity and recept ...... pontaneously hypertensive rat.
@en
Proteinase activity and recept ...... pontaneously hypertensive rat.
@nl
P2860
P1433
P1476
Proteinase activity and recept ...... pontaneously hypertensive rat.
@en
P2093
Frank A DeLano
Geert W Schmid-Schönbein
P2860
P304
P356
10.1161/HYPERTENSIONAHA.107.104356
P407
P577
2008-07-07T00:00:00Z