Metabotropic glutamate receptor 1 (mGluR1) and 5 (mGluR5) regulate late phases of LTP and LTD in the hippocampal CA1 region in vitro.
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Fluoride and arsenic exposure impairs learning and memory and decreases mGluR5 expression in the hippocampus and cortex in ratsDeleterious GRM1 mutations in schizophreniaNMDA receptors, mGluR5, and endocannabinoids are involved in a cascade leading to hippocampal long-term depressionMGluR5 mediates the interaction between late-LTP, network activity, and learningmGluR5 positive allosteric modulators facilitate both hippocampal LTP and LTD and enhance spatial learningCognitive effects of Group I metabotropic glutamate receptor ligands in the context of drug addiction.Successful cognitive aging in rats: a role for mGluR5 glutamate receptors, homer 1 proteins and downstream signaling pathways.Pharmacological reversal of synaptic plasticity deficits in the mouse model of fragile X syndrome by group II mGluR antagonist or lithium treatment.Hippocampal metaplasticity is required for the formation of temporal associative memories.The role of the tripartite glutamatergic synapse in the pathophysiology of Alzheimer's disease.Novel interactive partners of neuroligin 3: new aspects for pathogenesis of autism.Role of mGluR5 neurotransmission in reinstated cocaine-seekingProtein Synthesis Inhibitors Did Not Interfere with Long-Term Depression Induced either Electrically in Juvenile Rats or Chemically in Middle-Aged Rats.Roles of mGluR5 in synaptic function and plasticity of the mouse thalamocortical pathway.Extracellular calcium modulates actions of orthosteric and allosteric ligands on metabotropic glutamate receptor 1α.Social Communication is an Emerging Target for Pharmacotherapy in Autism Spectrum Disorder - A Review of the Literature on Potential Agents.Metabotropic glutamate receptor-mediated long-term depression: molecular mechanisms.Intracellular mGluR5 can mediate synaptic plasticity in the hippocampus.Group 1 metabotropic glutamate receptor function and its regulation of learning and memory in the aging brainmGlu1 receptor as a drug target for treatment of substance use disorders: time to gather stones together?Hippocampal metabotropic glutamate receptor long-term depression in health and disease: focus on mitogen-activated protein kinase pathways.Molecular and cellular aspects of age-related cognitive decline and Alzheimer's disease.The Role of mGlu Receptors in Hippocampal Plasticity Deficits in Neurological and Psychiatric Disorders: Implications for Allosteric Modulators as Novel Therapeutic Strategies.Metabotropic glutamate receptor 1 recycles to the cell surface in protein phosphatase 2A-dependent manner in non-neuronal and neuronal cell lines.Rescue of synaptic plasticity and spatial learning deficits in the hippocampus of Homer1 knockout mice by recombinant Adeno-associated viral gene delivery of Homer1c.NMDA receptor-mediated long-term alterations in epileptiform activity in experimental chronic epilepsyEarly-life seizures alter synaptic calcium-permeable AMPA receptor function and plasticity.Synaptic depression in the CA1 region of freely behaving mice is highly dependent on afferent stimulation parameters.Venus fly trap domain of mGluR1 functions as a dominant negative against group I mGluR signaling.Separate Ionotropic and Metabotropic Glutamate Receptor Functions in Depotentiation vs. LTP: A Distinct Role for Group1 mGluR Subtypes and NMDARs.Involvement of the metabotropic glutamate receptor mGluR5 in NMDA receptor-dependent, learning-facilitated long-term depression in CA1 synapses.Converging signal on ERK1/2 activity regulates group I mGluR-mediated Arc transcription.Place field stability requires the metabotropic glutamate receptor, mGlu5.Kinases of eIF2a Switch Translation of mRNA Subset during Neuronal Plasticity.Synaptic ionotropic glutamate receptors and plasticity are developmentally altered in the CA1 field of Fmr1 knockout mice.Effects of the Positive Allosteric Modulator of Metabotropic Glutamate Receptor 5, VU-29, on Impairment of Novel Object Recognition Induced by Acute Ethanol and Ethanol Withdrawal in Rats.Hippocampal long-term depression in freely behaving mice requires the activation of beta-adrenergic receptors.Endogenous hippocampal LTD that is enabled by spatial object recognition requires activation of NMDA receptors and the metabotropic glutamate receptor, mGlu5.Enhancement of social novelty discrimination by positive allosteric modulators at metabotropic glutamate 5 receptors: adolescent administration prevents adult-onset deficits induced by neonatal treatment with phencyclidine.Frequency dependency of NMDA receptor-dependent synaptic plasticity in the hippocampal CA1 region of freely behaving mice.
P2860
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P2860
Metabotropic glutamate receptor 1 (mGluR1) and 5 (mGluR5) regulate late phases of LTP and LTD in the hippocampal CA1 region in vitro.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
@zh-hant
name
Metabotropic glutamate recepto ...... ppocampal CA1 region in vitro.
@en
type
label
Metabotropic glutamate recepto ...... ppocampal CA1 region in vitro.
@en
prefLabel
Metabotropic glutamate recepto ...... ppocampal CA1 region in vitro.
@en
P2860
P1476
Metabotropic glutamate recepto ...... ppocampal CA1 region in vitro.
@en
P2093
Sergey Neyman
P2860
P304
P356
10.1111/J.1460-9568.2008.06109.X
P407
P577
2008-03-01T00:00:00Z