Stereospecificity of ketoreductase domains 1 and 2 of the tylactone modular polyketide synthase.
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Crystal Structures of Dehydratase Domains from the Curacin Polyketide Biosynthetic PathwayStructural and Biochemical Analyses of Regio- and Stereospecificities Observed in a Type II Polyketide KetoreductaseThe Determinants of Activity and Specificity in Actinorhodin Type II Polyketide KetoreductaseStructure and Stereospecificity of the Dehydratase Domain from the Terminal Module of the Rifamycin Polyketide SynthaseInsights into radicicol biosynthesis via heterologous synthesis of intermediates and analogsMechanism and stereospecificity of a fully saturating polyketide synthase module: nanchangmycin synthase module 2 and its dehydratase domain.Enediyne polyketide synthases stereoselectively reduce the β-ketoacyl intermediates to β-D-hydroxyacyl intermediates in enediyne core biosynthesis.Polyketide intermediate mimics as probes for revealing cryptic stereochemistry of ketoreductase domains.Essential role of the donor acyl carrier protein in stereoselective chain translocation to a fully reducing module of the nanchangmycin polyketide synthaseEpimerase and Reductase Activities of Polyketide Synthase Ketoreductase Domains Utilize the Same Conserved Tyrosine and Serine Residues.Stereochemistry of reductions catalyzed by methyl-epimerizing ketoreductase domains of polyketide synthases.Coupled methyl group epimerization and reduction by polyketide synthase ketoreductase domains. Ketoreductase-catalyzed equilibrium isotope exchange.Structural insights into nonribosomal peptide enzymatic assembly linesPolyketide stereocontrol: a study in chemical biology.The structures of type I polyketide synthases.Vinylogous Dehydration by a Polyketide Dehydratase Domain in Curacin Biosynthesis.The biochemical basis for stereochemical control in polyketide biosynthesis.A fungal ketoreductase domain that displays substrate-dependent stereospecificity.Stereospecificity of the dehydratase domain of the erythromycin polyketide synthase.Tylosin polyketide synthase module 3: stereospecificity, stereoselectivity and steady-state kinetic analysis of β-processing domains via diffusible, synthetic substrates.A trans-acting ketoreductase in biosynthesis of a symmetric polyketide dimer SIA7248.Elucidation of the Stereospecificity of C-Methyltransferases from trans-AT Polyketide Synthases.Elucidation of the Cryptic Methyl Group Epimerase Activity of Dehydratase Domains from Modular Polyketide Synthases Using a Tandem Modules Epimerase Assay.Mechanism and Stereochemistry of Polyketide Chain Elongation and Methyl Group Epimerization in Polyether Biosynthesis.Insights into the stereospecificity of ketoreduction in a modular polyketide synthase.Substrate-dependent stereospecificity of Tyl-KR1: an isolated polyketide synthase ketoreductase domain from Streptomyces fradiae.
P2860
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P2860
Stereospecificity of ketoreductase domains 1 and 2 of the tylactone modular polyketide synthase.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
@zh-hant
name
Stereospecificity of ketoreduc ...... e modular polyketide synthase.
@en
Stereospecificity of ketoreduc ...... e modular polyketide synthase.
@nl
type
label
Stereospecificity of ketoreduc ...... e modular polyketide synthase.
@en
Stereospecificity of ketoreduc ...... e modular polyketide synthase.
@nl
prefLabel
Stereospecificity of ketoreduc ...... e modular polyketide synthase.
@en
Stereospecificity of ketoreduc ...... e modular polyketide synthase.
@nl
P2093
P2860
P356
P1476
Stereospecificity of ketoreduc ...... e modular polyketide synthase.
@en
P2093
Adrian Keatinge-Clay
Alice Y Chen
Chaitan Khosla
Chiara R Valenzano
David E Cane
Roselyne Castonguay
P2860
P304
11598-11599
P356
10.1021/JA804453P
P407
P577
2008-08-12T00:00:00Z