V(D)J recombination: signal and coding joint resolution are uncoupled and depend on parallel synapsis of the sites.
about
Transposition mediated by RAG1 and RAG2 and the evolution of the adaptive immune system.Functional analysis of coordinated cleavage in V(D)J recombination.RAG-2 promotes heptamer occupancy by RAG-1 in the assembly of a V(D)J initiation complex.Postcleavage sequence specificity in V(D)J recombination.The DDE motif in RAG-1 is contributed in trans to a single active site that catalyzes the nicking and transesterification steps of V(D)J recombinationThe RAG proteins in V(D)J recombination: more than just a nuclease.A RAG-1/RAG-2 tetramer supports 12/23-regulated synapsis, cleavage, and transposition of V(D)J recombination signals.Nicking is asynchronous and stimulated by synapsis in 12/23 rule-regulated V(D)J cleavage.Single-molecule analysis of RAG-mediated V(D)J DNA cleavage.V(D)J recombination: how to tame a transposase.Fluorescence resonance energy transfer analysis of recombination signal sequence configuration in the RAG1/2 synaptic complex.Ku86 is not required for protection of signal ends or for formation of nonstandard V(D)J recombination products.Enhancer control of local accessibility to V(D)J recombinase.Abnormal deletions in the T-cell receptor delta locus of mouse thymocytes.Full-length RAG1 promotes contact with coding and intersignal sequences in RAG protein complexes bound to recombination signals paired in cis.Accessibility of chromosomal recombination breaks in nuclei of wild-type and DNA-PKcs-deficient cells.Initial stages of V(D)J recombination: the organization of RAG1/2 and RSS DNA in the postcleavage complex.Synapsis of recombination signal sequences located in cis and DNA underwinding in V(D)J recombination.The nicking step in V(D)J recombination is independent of synapsis: implications for the immune repertoireThe RAG-HMG1 complex enforces the 12/23 rule of V(D)J recombination specifically at the double-hairpin formation stepV(D)J recombination coding junction formation without DNA homology: processing of coding termini.Unequal signal and coding joint formation in human V(D)J recombination.V(D)J recombination in mammalian cell mutants defective in DNA double-strand break repair.Ku80 is required for immunoglobulin isotype switchingWarner-Lambert/Parke-Davis Award Lecture. Pathological and physiological double-strand breaks: roles in cancer, aging, and the immune system.V(D)J recombination activity in human hematopoietic cells: correlation with developmental stage and genome stability.
P2860
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P2860
V(D)J recombination: signal and coding joint resolution are uncoupled and depend on parallel synapsis of the sites.
description
1993 nî lūn-bûn
@nan
1993年の論文
@ja
1993年学术文章
@wuu
1993年学术文章
@zh
1993年学术文章
@zh-cn
1993年学术文章
@zh-hans
1993年学术文章
@zh-my
1993年学术文章
@zh-sg
1993年學術文章
@yue
1993年學術文章
@zh-hant
name
V(D)J recombination: signal an ...... arallel synapsis of the sites.
@en
type
label
V(D)J recombination: signal an ...... arallel synapsis of the sites.
@en
prefLabel
V(D)J recombination: signal an ...... arallel synapsis of the sites.
@en
P2860
P356
P1476
V(D)J recombination: signal an ...... arallel synapsis of the sites.
@en
P2093
K M Sheehan
M R Lieber
P2860
P304
P356
10.1128/MCB.13.3.1363
P407
P577
1993-03-01T00:00:00Z