Inhibition of PTP1B by trodusquemine (MSI-1436) causes fat-specific weight loss in diet-induced obese mice.
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H2S-Induced sulfhydration of the phosphatase PTP1B and its role in the endoplasmic reticulum stress responseOrder, Disorder, and Everything in BetweenObesity pharmacotherapy: current perspectives and future directionsProtein-tyrosine Phosphatase and Kinase Specificity in Regulation of SRC and Breast Tumor KinaseThe cellular and molecular bases of leptin and ghrelin resistance in obesity.Discovery of a novel series of inhibitors of lymphoid tyrosine phosphatase with activity in human T cells.Targeting the disordered C terminus of PTP1B with an allosteric inhibitorShp2 protein tyrosine phosphatase inhibitor activity of estramustine phosphate and its triterpenoid analogs.MSI-1436 reduces acute food intake without affecting dopamine transporter activity.New pharmacological perspectives for the leptin receptor in the treatment of obesityTargeting protein tyrosine phosphatases for anticancer drug discovery.Significance of endangered and threatened plant natural products in the control of human disease.Current and future drug targets in weight managementEffects of hepatic protein tyrosine phosphatase 1B and methionine restriction on hepatic and whole-body glucose and lipid metabolism in mice.Protein-tyrosine phosphatase 1B antagonized signaling by insulin-like growth factor-1 receptor and kinase BRK/PTK6 in ovarian cancer cells.Brain signaling systems in the Type 2 diabetes and metabolic syndrome: promising target to treat and prevent these diseases.Protein Tyrosine Phosphatase 1B (PTP1B): A Potential Target for Alzheimer's Therapy?Novel curcumin derivative CNB-001 mitigates obesity-associated insulin resistance.Protein tyrosine phosphatases as drug targets: strategies and challenges of inhibitor development.Protein tyrosine phosphatase structure-function relationships in regulation and pathogenesis.Leptin signalling pathways in hypothalamic neurons.Renaissance of leptin for obesity therapy.Receptor-Interacting Protein 140 Orchestrates the Dynamics of Macrophage M1/M2 Polarization.Targeting hepatic glucose metabolism in the treatment of type 2 diabetes.Molecular Pathways: Targeting Protein Tyrosine Phosphatases in Cancer.Inhibitors of Protein Tyrosine Phosphatase 1B from Marine Natural Products.Targeting Tyrosine Phosphatases: Time to End the Stigma.1H-2,3-dihydroperimidine derivatives: a new class of potent protein tyrosine phosphatase 1B inhibitors.Obesity Drug Update: The Lost Decade?Novel Mixed-Type Inhibitors of Protein Tyrosine Phosphatase 1B. Kinetic and Computational Studies.Protein tyrosine phosphatases in cardiac physiology and pathophysiology.The protein tyrosine phosphatase 1B inhibitor MSI-1436 stimulates regeneration of heart and multiple other tissues.
P2860
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P2860
Inhibition of PTP1B by trodusquemine (MSI-1436) causes fat-specific weight loss in diet-induced obese mice.
description
2010 nî lūn-bûn
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2010年の論文
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2010年学术文章
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2010年学术文章
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2010年学术文章
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2010年学术文章
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2010年学术文章
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2010年学术文章
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name
Inhibition of PTP1B by trodusq ...... ss in diet-induced obese mice.
@en
Inhibition of PTP1B by trodusquemine
@nl
type
label
Inhibition of PTP1B by trodusq ...... ss in diet-induced obese mice.
@en
Inhibition of PTP1B by trodusquemine
@nl
prefLabel
Inhibition of PTP1B by trodusq ...... ss in diet-induced obese mice.
@en
Inhibition of PTP1B by trodusquemine
@nl
P2093
P2860
P356
P1433
P1476
Inhibition of PTP1B by trodusq ...... ss in diet-induced obese mice.
@en
P2093
Henry R Wolfe
Inez A Ruiz-White
Kristen A Lantz
Michael P McLane
Mitchell F Roitman
Sonia L Planey
Susan G Emeigh Hart
P2860
P304
P356
10.1038/OBY.2009.444
P577
2010-01-14T00:00:00Z