Folding of the natural hammerhead ribozyme is enhanced by interaction of auxiliary elements.
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Functional hammerhead ribozymes naturally encoded in the genome of Arabidopsis thalianaFrom alpaca to zebrafish: hammerhead ribozymes wherever you lookEfficient ligation of the Schistosoma hammerhead ribozymeThe ubiquitous hammerhead ribozymeLow-magnesium, trans-cleavage activity by type III, tertiary stabilized hammerhead ribozymes with stem 1 discontinuities.Solvent Structure and Hammerhead Ribozyme CatalysisCapturing Hammerhead Ribozyme Structures in Action by Modulating General Base CatalysisTertiary contacts distant from the active site prime a ribozyme for catalysis.Self-assembly Controls Self-cleavage of HHR from ASBVd (-): a Combined SANS and Modeling StudyFrequency of RNA-RNA interaction in a model of the RNA World.Identification of inhibitors of ribozyme self-cleavage in mammalian cells via high-throughput screening of chemical libraries.The hammerhead ribozyme: structure, catalysis, and gene regulationDo the hairpin and VS ribozymes share a common catalytic mechanism based on general acid-base catalysis? A critical assessment of available experimental data.Selecting RNA aptamers for synthetic biology: investigating magnesium dependence and predicting binding affinityEnhanced product stability in the hammerhead ribozyme.Precise mapping of RNA tertiary structure via nanometer distance measurements with double electron-electron resonance spectroscopyNucleotides that are essential but not conserved; a sufficient L-tryptophan site in RNA.The catalytic diversity of RNAs.Extraordinary rates of transition metal ion-mediated ribozyme catalysisVariables and strategies in development of therapeutic post-transcriptional gene silencing agentsTopological rearrangement yields structural stabilization and interhelical distance constraints in the Kin.46 self-phosphorylating ribozyme.Organelle trafficking of chimeric ribozymes and genetic manipulation of mitochondria.Conformational heterogeneity and the determinants of tertiary stabilization in the hammerhead ribozyme from Dolichopoda cave crickets.Folding of the hammerhead ribozyme: pyrrolo-cytosine fluorescence separates core folding from global folding and reveals a pH-dependent conformational change.Distinct reaction pathway promoted by non-divalent-metal cations in a tertiary stabilized hammerhead ribozyme.Metal-ion-dependent folding of a uranyl-specific DNAzyme: insight into function from fluorescence resonance energy transfer studies.A loop loop interaction and a K-turn motif located in the lysine aptamer domain are important for the riboswitch gene regulation control.Biophysical Approaches to Bacterial Gene Regulation by Riboswitches.Ribozyme catalysis: not different, just worse.A versatile cis-blocking and trans-activation strategy for ribozyme characterization.Hinge stiffness is a barrier to RNA foldingRole of Mg2+ in hammerhead ribozyme catalysis from molecular simulationIntermolecular domain docking in the hairpin ribozyme: metal dependence, binding kinetics and catalysisMetal ion specificities for folding and cleavage activity in the Schistosoma hammerhead ribozymeLeakage and slow allostery limit performance of single drug-sensing aptazyme molecules based on the hammerhead ribozyme.Analysis of branched nucleic acid structure using comparative gel electrophoresis.Metal ion dependence, thermodynamics, and kinetics for intramolecular docking of a GAAA tetraloop and receptor connected by a flexible linker.Catalytic diversity of extended hammerhead ribozymesActivity, folding and Z-DNA formation of the 8-17 DNAzyme in the presence of monovalent ions.Improved design of hammerhead ribozyme for selective digestion of target RNA through recognition of site-specific adenosine-to-inosine RNA editing.
P2860
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P2860
Folding of the natural hammerhead ribozyme is enhanced by interaction of auxiliary elements.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年学术文章
@wuu
2004年学术文章
@zh
2004年学术文章
@zh-cn
2004年学术文章
@zh-hans
2004年学术文章
@zh-my
2004年学术文章
@zh-sg
2004年學術文章
@yue
2004年學術文章
@zh-hant
name
Folding of the natural hammerh ...... raction of auxiliary elements.
@en
Folding of the natural hammerh ...... raction of auxiliary elements.
@nl
type
label
Folding of the natural hammerh ...... raction of auxiliary elements.
@en
Folding of the natural hammerh ...... raction of auxiliary elements.
@nl
prefLabel
Folding of the natural hammerh ...... raction of auxiliary elements.
@en
Folding of the natural hammerh ...... raction of auxiliary elements.
@nl
P2093
P2860
P356
P1433
P1476
Folding of the natural hammerh ...... eraction of auxiliary elements
@en
P2093
Anastasia Khvorova
David M J Lilley
Sumedha D Jayasena
Timothy J Wilson
P2860
P304
P356
10.1261/RNA.5268404
P407
P577
2004-05-01T00:00:00Z