A pyrazolato-bridged dinuclear platinum(II) complex induces only minor distortions upon DNA-binding.
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Protein Recognition in Drug-Induced DNA Alkylation: When the Moonlight Protein GAPDH Meets S23906-1/DNA Minor Groove AdductsDNA-Destabilizing Agents as an Alternative Approach for Targeting DNA: Mechanisms of Action and Cellular ConsequencesPhotoinduced interactions of two dirhodium complexes with d(GTCGAC)2 probed by 2D NOESY.Modeling anticancer drug-DNA interactions via mixed QM/MM molecular dynamics simulations.Chromatin folding and DNA replication inhibition mediated by a highly antitumor-active tetrazolato-bridged dinuclear platinum(II) complexAtomistic-level portrayal of drug-DNA Interplay: a history of courtships and meetings revealed by molecular simulations.Highly efficient uptake into cisplatin-resistant cells and the isomerization upon coordinative DNA binding of anticancer tetrazolato-bridged dinuclear platinum(II) complexes.Synthesis of antitumor azolato-bridged dinuclear platinum(ii) complexes with in vivo antitumor efficacy and unique in vitro cytotoxicity profiles.Dinuclear Pt(II)-bisphosphonate complexes: a scaffold for multinuclear or different oxidation state platinum drugs.An in vivo highly antitumor-active tetrazolato-bridged dinuclear platinum(II) complex largely circumvents in vitro cisplatin resistance: two linkage isomers yield the same product upon reaction with 9-ethylguanine but exhibit different cytotoxic proA tetrazolato-bridged dinuclear platinum(II) complex exhibits markedly high in vivo antitumor activity against pancreatic cancer.Non-traditional platinum compounds for improved accumulation, oral bioavailability, and tumor targeting.Cisplatin adducts on a GGG sequence within a DNA duplex studied by NMR spectroscopy and molecular dynamics simulations.Multiple Condensation Reactions Involving Pt(II) /Pd(II) -OH2 , Pt-NH3 , and Cytosine-NH2 Groups: New Twists in Cisplatin-Nucleobase Chemistry.
P2860
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P2860
A pyrazolato-bridged dinuclear platinum(II) complex induces only minor distortions upon DNA-binding.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
A pyrazolato-bridged dinuclear ...... distortions upon DNA-binding.
@en
type
label
A pyrazolato-bridged dinuclear ...... distortions upon DNA-binding.
@en
prefLabel
A pyrazolato-bridged dinuclear ...... distortions upon DNA-binding.
@en
P2093
P2860
P356
P1476
A pyrazolato-bridged dinuclear ...... distortions upon DNA-binding.
@en
P2093
Jan Reedijk
Jan-Maarten Teuben
Jirí Kozelka
Miguel-Angel Elizondo-Riojas
Seiji Komeda
Stéphane Teletchéa
P2860
P304
P356
10.1002/CHEM.200500923
P407
P577
2006-05-01T00:00:00Z