Homeobox gene Nkx6.1 lies downstream of Nkx2.2 in the major pathway of beta-cell formation in the pancreas.
about
Neuroendocrine differentiation factor, IA-1, is a transcriptional repressor and contains a specific DNA-binding domain: identification of consensus IA-1 binding sequenceIA1 is NGN3-dependent and essential for differentiation of the endocrine pancreas.The transcription factor Rfx3 regulates beta-cell differentiation, function, and glucokinase expressionNotch signaling controls multiple steps of pancreatic differentiationThe MafA transcription factor appears to be responsible for tissue-specific expression of insulinStimulation of human and rat islet beta-cell proliferation with retention of function by the homeodomain transcription factor Nkx6.1Engineering tissue from human embryonic stem cellsMafB is required for islet beta cell maturationRecapitulation of embryonic neuroendocrine differentiation in adult human pancreatic duct cells expressing neurogenin 3Contextual interactions determine whether the Drosophila homeodomain protein, Vnd, acts as a repressor or activatorGeneration of β cells from human pluripotent stem cells: are we there yet?Genes involved in pancreatic islet cell rejuvenationDerivation of insulin-producing beta-cells from human pluripotent stem cellsReversal of hyperglycemia by insulin-secreting rat bone marrow- and blastocyst-derived hypoblast stem cell-like cellsNatural history of β-cell adaptation and failure in type 2 diabetesToward beta cell replacement for diabetesTranscription factor regulation of pancreatic organogenesis, differentiation and maturationGhrelin cells replace insulin-producing beta cells in two mouse models of pancreas developmentGata6 is an important regulator of mouse pancreas developmentRequirement of the tissue-restricted homeodomain transcription factor Nkx6.3 in differentiation of gastrin-producing G cells in the stomach antrumThe Krüppel-like zinc finger protein Glis3 directly and indirectly activates insulin gene transcriptionLoss of Myt1 function partially compromises endocrine islet cell differentiation and pancreatic physiological function in the mouseIdentification of the bHLH factor Math6 as a novel component of the embryonic pancreas transcriptional networkGenetic identification of a novel NeuroD1 function in the early differentiation of islet alpha, PP and epsilon cellsSOX9 is required for maintenance of the pancreatic progenitor cell poolMembers of the large Maf transcription family regulate insulin gene transcription in islet beta cellsNkx6-1 controls the identity and fate of red nucleus and oculomotor neurons in the mouse midbrainNkx2.2-repressor activity is sufficient to specify alpha-cells and a small number of beta-cells in the pancreatic isletThe Nkx6.1 homeodomain transcription factor suppresses glucagon expression and regulates glucose-stimulated insulin secretion in islet beta cells.Nkx6.1 regulates islet β-cell proliferation via Nr4a1 and Nr4a3 nuclear receptorsExpression of Groucho/TLE proteins during pancreas developmentDachshund homologues play a conserved role in islet cell developmentThe zinc-finger factor Insm1 (IA-1) is essential for the development of pancreatic beta cells and intestinal endocrine cellsPdx1 and Ngn3 overexpression enhances pancreatic differentiation of mouse ES cell-derived endoderm populationThe Cdk4-E2f1 pathway regulates early pancreas development by targeting Pdx1+ progenitors and Ngn3+ endocrine precursors.Transdifferentiation of pancreatic cells by loss of contact-mediated signalingPharmacological induction of pancreatic islet cell transdifferentiation: relevance to type I diabetesDeciphering c-MYC-regulated genes in two distinct tissues.Preservation of proliferating pancreatic progenitor cells by Delta-Notch signaling in the embryonic chicken pancreas.Expression of zebrafish pax6b in pancreas is regulated by two enhancers containing highly conserved cis-elements bound by PDX1, PBX and PREP factors
P2860
Q24292295-3A7E8C9E-EF83-48AF-8E66-1FECFDB917D4Q24306349-A6972C51-57AA-4A1B-BAF9-7025E11A5BDBQ24307633-21F301DB-04DC-4CB7-8A2C-4C64C05009ECQ24569636-10A6254C-EFB8-4348-85FF-571111BB3F86Q24626092-0E99C242-69A1-4A72-A80E-DC297F83529AQ24641935-784B537F-D725-444E-9B18-532B92A68A72Q24657199-0A5036E8-B194-4252-A8D8-E754D281C9B8Q24669977-48D752CA-8A5B-441B-A45D-E8F235F227BFQ24674625-8EFF0D24-8550-4AB9-9A97-8C56DDC2FFD9Q24793257-CCEB7E41-B011-4774-A201-3C87E87ABFF7Q26823732-3B7EFA3B-7625-45E7-8CD1-B949F190B97EQ26827270-77F97D17-71C5-43F1-99F1-94A664E20ED2Q27011814-6335C980-5565-44B0-BCEB-29BB196F092BQ27320637-5070995D-FBB0-4345-B683-A667953A84ACQ28082002-A4155292-A367-4C24-91D0-D3B40C602257Q28083650-2FE4B784-F605-47D2-A93F-A30604EDC3D2Q28083955-9C4E4749-5F74-4AF9-9338-806BC04A6BB5Q28245759-DB355A7C-8FF7-421B-9DFA-601F7E5F1EDFQ28505084-4A3A7876-A685-4712-9B35-8F15169699E6Q28507588-D2CAB7B7-18A1-43B0-BA56-52770B01870FQ28507859-AF001D7B-FC16-4711-A898-7AD30C1A6F84Q28507900-D118D46C-693B-486D-9DB1-9509F10450BAQ28509631-98A4D756-08D6-4112-8BB3-BCE6B2EF90F2Q28509809-6A468551-5A4F-4560-BB55-710A978FDC30Q28510325-E0941E3F-516C-4D91-8139-B1E2437794B4Q28510639-80052C79-7570-4B18-AFEB-022E79D51931Q28512715-9DE961C8-9120-4840-B5E3-6426A18ED2ECQ28512983-888A2445-F19B-4C39-A625-74A28384C0EBQ28575562-C8F67301-A4EA-4723-A516-608917F30E2FQ28578613-3A1AC5A6-F96B-488D-AA6D-6D715B0FADBAQ28583875-ACB2F06F-52E5-4BB0-A2DE-F29FEBB03370Q28586023-544545A0-C0BE-4466-A6ED-A14AB943EA1BQ28588538-6C38ED3C-D800-4BBF-B7D4-CC50CE23F198Q28740445-9A0AE063-FC78-4C13-8BD2-2B0CF0C734FFQ30499855-96BD1ABF-8A55-49D2-9E93-F8B92652F2AAQ30543433-BE35A923-5AAA-4800-A592-6AC8E8F91623Q30585966-2FD7CCBD-7AC1-4165-8207-E2B2CB5A4C30Q31031668-E1B35D6D-A9A8-4A04-94C6-6B3899A302CEQ33287045-818BC5F5-C137-4597-A940-C1D308E401E7Q33335336-77F64223-9D68-4779-B870-D9CB2F9D10D4
P2860
Homeobox gene Nkx6.1 lies downstream of Nkx2.2 in the major pathway of beta-cell formation in the pancreas.
description
2000 nî lūn-bûn
@nan
2000年の論文
@ja
2000年学术文章
@wuu
2000年学术文章
@zh
2000年学术文章
@zh-cn
2000年学术文章
@zh-hans
2000年学术文章
@zh-my
2000年学术文章
@zh-sg
2000年學術文章
@yue
2000年學術文章
@zh-hant
name
Homeobox gene Nkx6.1 lies down ...... ell formation in the pancreas.
@en
Homeobox gene Nkx6.1 lies down ...... ell formation in the pancreas.
@nl
type
label
Homeobox gene Nkx6.1 lies down ...... ell formation in the pancreas.
@en
Homeobox gene Nkx6.1 lies down ...... ell formation in the pancreas.
@nl
prefLabel
Homeobox gene Nkx6.1 lies down ...... ell formation in the pancreas.
@en
Homeobox gene Nkx6.1 lies down ...... ell formation in the pancreas.
@nl
P2093
P921
P1433
P1476
Homeobox gene Nkx6.1 lies down ...... cell formation in the pancreas
@en
P2093
A Hayes-Jordan
F Dela Cruz
J Kalamaras
V Schwitzgebel
P304
P407
P577
2000-12-01T00:00:00Z