Continuous cultivation of Trypanosoma brucei blood stream forms in a medium containing a low concentration of serum protein without feeder cell layers.
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Early invasion of brain parenchyma by African trypanosomesDifferences between Trypanosoma brucei gambiense groups 1 and 2 in their resistance to killing by trypanolytic factor 1The killing of African trypanosomes by ethidium bromideTelomeric expression sites are highly conserved in Trypanosoma bruceiSCYX-7158, an orally-active benzoxaborole for the treatment of stage 2 human African trypanosomiasisC-terminal mutants of apolipoprotein L-I efficiently kill both Trypanosoma brucei brucei and Trypanosoma brucei rhodesienseCold shock and regulation of surface protein trafficking convey sensitization to inducers of stage differentiation in Trypanosoma bruceiTrypanosoma brucei CTP synthetase: a target for the treatment of African sleeping sicknessTrypanosoma brucei BRCA2 acts in antigenic variation and has undergone a recent expansion in BRC repeat number that is important during homologous recombinationActive VSG expression sites in Trypanosoma brucei are depleted of nucleosomesDissecting the essentiality of the bifunctional trypanothione synthetase-amidase in Trypanosoma brucei using chemical and genetic methodsEvidence for an interplay between cell cycle progression and the initiation of differentiation between life cycle forms of African trypanosomesDistinct roles of haptoglobin-related protein and apolipoprotein L-I in trypanolysis by human serumTelomere structure and shortening in telomerase-deficient Trypanosoma bruceiDistinct roles for two RAD51-related genes in Trypanosoma brucei antigenic variation.Melarsoprol cyclodextrin inclusion complexes as promising oral candidates for the treatment of human African trypanosomiasisCharacterization of Trypanosoma brucei dihydroorotate dehydrogenase as a possible drug target; structural, kinetic and RNAi studiesComparative structural, kinetic and inhibitor studies of Trypanosoma brucei trypanothione reductase with T. cruziCrystal Structures of Trypanosomal Histidyl-tRNA Synthetase Illuminate Differences between Eukaryotic and Prokaryotic HomologsChemical, genetic and structural assessment of pyridoxal kinase as a drug target in the African trypanosomeDiscovery of a Novel Class of Orally Active Trypanocidal N -Myristoyltransferase InhibitorsModulation of the Immune Response by Nematode Secreted Acetylcholinesterase Revealed by Heterologous Expression in Trypanosoma musculiA pyruvate-proton symport and an H+-ATPase regulate the intracellular pH of Trypanosoma brucei at different stages of its life cycleAdenosine analogues as selective inhibitors of glyceraldehyde-3-phosphate dehydrogenase of Trypanosomatidae via structure-based drug designCytosolic peroxidases protect the lysosome of bloodstream African trypanosomes from iron-mediated membrane damageRegulated expression of an essential allosteric activator of polyamine biosynthesis in African trypanosomesFunctional characterisation and drug target validation of a mitotic kinesin-13 in Trypanosoma brucei2,4-Diaminopyrimidines as potent inhibitors of Trypanosoma brucei and identification of molecular targets by a chemical proteomics approachIdentification of compounds with anti-proliferative activity against Trypanosoma brucei brucei strain 427 by a whole cell viability based HTS campaignPyrimidine biosynthesis is not an essential function for Trypanosoma brucei bloodstream formsAquaporin 2 mutations in Trypanosoma brucei gambiense field isolates correlate with decreased susceptibility to pentamidine and melarsoprolHighly sensitive in vivo imaging of Trypanosoma brucei expressing "red-shifted" luciferaseHandling uncertainty in dynamic models: the pentose phosphate pathway in Trypanosoma bruceiRevisiting the central metabolism of the bloodstream forms of Trypanosoma brucei: production of acetate in the mitochondrion is essential for parasite viabilityRegulators of Trypanosoma brucei cell cycle progression and differentiation identified using a kinome-wide RNAi screenA panel of Trypanosoma brucei strains tagged with blue and red-shifted luciferases for bioluminescent imaging in murine infection modelsSpecific Cell Targeting Therapy Bypasses Drug Resistance Mechanisms in African TrypanosomiasisQuantitative Proteomics Uncovers Novel Factors Involved in Developmental Differentiation of Trypanosoma bruceiNew Trypanosoma evansi Type B Isolates from Ethiopian Dromedary CamelsGenomic and Proteomic Studies on the Mode of Action of Oxaboroles against the African Trypanosome
P2860
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P2860
Continuous cultivation of Trypanosoma brucei blood stream forms in a medium containing a low concentration of serum protein without feeder cell layers.
description
1989 nî lūn-bûn
@nan
1989年の論文
@ja
1989年学术文章
@wuu
1989年学术文章
@zh-cn
1989年学术文章
@zh-hans
1989年学术文章
@zh-my
1989年学术文章
@zh-sg
1989年學術文章
@yue
1989年學術文章
@zh
1989年學術文章
@zh-hant
name
Continuous cultivation of Tryp ...... in without feeder cell layers.
@en
Continuous cultivation of Tryp ...... in without feeder cell layers.
@nl
type
label
Continuous cultivation of Tryp ...... in without feeder cell layers.
@en
Continuous cultivation of Tryp ...... in without feeder cell layers.
@nl
prefLabel
Continuous cultivation of Tryp ...... in without feeder cell layers.
@en
Continuous cultivation of Tryp ...... in without feeder cell layers.
@nl
P1476
Continuous cultivation of Tryp ...... in without feeder cell layers.
@en
P2093
P304
P577
1989-12-01T00:00:00Z