Effects of chronic exposure to cocaine are regulated by the neuronal protein Cdk5. - Wikidata - awgldk - TriplyDB

Effects of chronic exposure to cocaine are regulated by the neuronal protein Cdk5.

Effects of chronic exposure to cocaine are regulated by the neuronal protein Cdk5.

http://www.wikidata.org/entity/Q43553698

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Mechanisms for the modulation of dopamine d(1) receptor signaling in striatal neurons Transcriptional mechanisms of drug addiction Molecular neurobiology of addiction: what’s all the (Δ)FosB about?Natural and Drug Rewards Act on Common Neural Plasticity Mechanisms with FosB as a Key Mediator DARPP-32 mediates the actions of multiple drugs of abuse Methylphenidate-induced dendritic spine formation and DeltaFosB expression in nucleus accumbens Transcriptional and epigenetic mechanisms of addiction Striatal dysregulation of Cdk5 alters locomotor responses to cocaine, motor learning, and dendritic morphology DeltaFosB: a sustained molecular switch for addiction Cellular basis of memory for addiction ΔFosB in the nucleus accumbens is critical for reinforcing effects of sexual reward The epigenetic landscape of addiction Review. Transcriptional mechanisms of addiction: role of DeltaFosB Epigenetic mechanisms in drug addiction Epigenetic mediation of environmental influences in major psychotic disorders Genome-wide analysis of chromatin regulation by cocaine reveals a role for sirtuins Early life exposure to a high fat diet promotes long-term changes in dietary preferences and central reward signaling Adenosine A2A receptors and basal ganglia physiology Virogenetic and optogenetic mechanisms to define potential therapeutic targets in psychiatric disorders Molecular, cellular, and structural mechanisms of cocaine addiction: a key role for microRNAs The role of ventral striatal cAMP signaling in stress-induced behaviors.Calpain-mediated cleavage of the cyclin-dependent kinase-5 activator p39 to p29 AKT and CDK5/p35 mediate brain-derived neurotrophic factor induction of DARPP-32 in medium size spiny neurons in vitro A Tale of the Good and Bad: Remodeling of the Microtubule Network in the Brain by Cdk5 Regulation of hippocampal and behavioral excitability by cyclin-dependent kinase 5.Mechanisms of psychostimulant-induced structural plasticity Locomotor conditioning by amphetamine requires cyclin-dependent kinase 5 signaling in the nucleus accumbens Striatal signal transduction and drug addiction Targeted Epigenetic Remodeling of the Cdk5 Gene in Nucleus Accumbens Regulates Cocaine- and Stress-Evoked Behavior Cdk5 phosphorylates dopamine D2 receptor and attenuates downstream signaling Cdk5-FOXO3a axis: initially neuroprotective, eventually neurodegenerative in Alzheimer's disease models Electroacupuncture decreases excessive alcohol consumption involving reduction of FosB/ΔFosB levels in reward-related brain regions Cyclin-dependent kinase 5 governs learning and synaptic plasticity via control of NMDAR degradation Cocaine-induced proliferation of dendritic spines in nucleus accumbens is dependent on the activity of cyclin-dependent kinase-5 Signaling pathway adaptations and novel protein kinase A substrates related to behavioral sensitization to cocaine A developmentally regulated and psychostimulant-inducible novel rat gene mrt1 encoding PDZ-PX proteins isolated in the neocortex Delta FosB mediates epigenetic desensitization of the c-fos gene after chronic amphetamine exposure Attention-deficit/hyperactivity phenotype in mice lacking the cyclin-dependent kinase 5 cofactor p35 Perinatal abrogation of Cdk5 expression in brain results in neuronal migration defects Cyclin-dependent kinase 5 regulates dopaminergic and glutamatergic transmission in the striatum

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Effects of chronic exposure to cocaine are regulated by the neuronal protein Cdk5.

http://www.wikidata.org/entity/Q43553698

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2001年學術文章

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2001年學術文章

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2001年學術文章

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name

Effects of chronic exposure to cocaine are regulated by the neuronal protein Cdk5.

@en

Effects of chronic exposure to cocaine are regulated by the neuronal protein Cdk5.

@nl

type

label

Effects of chronic exposure to cocaine are regulated by the neuronal protein Cdk5.

@en

Effects of chronic exposure to cocaine are regulated by the neuronal protein Cdk5.

@nl

prefLabel

Effects of chronic exposure to cocaine are regulated by the neuronal protein Cdk5.

@en

Effects of chronic exposure to cocaine are regulated by the neuronal protein Cdk5.

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Effects of chronic exposure to cocaine are regulated by the neuronal protein Cdk5.

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A Nishi

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C C Ouimet

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G L Snyder

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J A Bibb

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J Chen

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J R Taylor

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Z K Sagawa

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Z Yan

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P2860

Phosphorylation of DARPP-32 by Cdk5 modulates dopamine signalling in neurons

Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches

Conversion of p35 to p25 deregulates Cdk5 activity and promotes neurodegeneration

Amplification of dopaminergic signaling by a positive feedback loop

Addiction, dopamine, and the molecular mechanisms of memory

Characterization of multiple phosphorylation sites on the AMPA receptor GluR1 subunit

Mice lacking p35, a neuronal specific activator of Cdk5, display cortical lamination defects, seizures, and adult lethality

Neuronal and behavioural abnormalities in striatal function in DARPP-32-mutant mice

Targeted disruption of the cyclin-dependent kinase 5 gene results in abnormal corticogenesis, neuronal pathology and perinatal death

Elimination of cocaine-induced hyperactivity and dopamine-mediated neurophysiological effects in dopamine D1 receptor mutant mice

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