A transient inhibition of mitochondrial ATP synthesis by nitric oxide synthase activation triggered apoptosis in primary cortical neurons.
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Knockdown of glutamate-cysteine ligase by small hairpin RNA reveals that both catalytic and modulatory subunits are essential for the survival of primary neuronsPeroxynitrite protects neurons against nitric oxide-mediated apoptosis. A key role for glucose-6-phosphate dehydrogenase activity in neuroprotectionCdk5 phosphorylates Cdh1 and modulates cyclin B1 stability in excitotoxicityAstrocyte NMDA receptors' activity sustains neuronal survival through a Cdk5-Nrf2 pathway.Liver proteome analysis in a rodent model of alcoholic steatosis.Different responses of astrocytes and neurons to nitric oxide: the role of glycolytically generated ATP in astrocyte protection.Nitric oxide and cell signaling pathways in mitochondrial-dependent apoptosis.The human Tp53 Arg72Pro polymorphism explains different functional prognosis in stroke.Response of the nitrergic system to activation of the neuroendocrine stress axis.Magnesium sulfate protects against the bioenergetic consequences of chronic glutamate receptor stimulationOxygen resuscitation after hypoxia ischemia stimulates prostaglandin pathway in rat cortex.Polychlorinated Biphenyls Induce Mitochondrial Dysfunction in SH-SY5Y Neuroblastoma Cells.γ-Glutamylcysteine detoxifies reactive oxygen species by acting as glutathione peroxidase-1 cofactor.Neuroprotective effects of 20(S)-protopanaxadiol against glutamate-induced mitochondrial dysfunction in PC12 cells.Excitotoxic stimulus stabilizes PFKFB3 causing pentose-phosphate pathway to glycolysis switch and neurodegenerationCdk5-mediated inhibition of APC/C-Cdh1 switches on the cyclin D1-Cdk4-pRb pathway causing aberrant S-phase entry of postmitotic neurons.Regulation of APC/C-Cdh1 and its function in neuronal survivalOptical and pharmacological tools to investigate the role of mitochondria during oxidative stress and neurodegeneration.PACAP38 protects rat cortical neurons against the neurotoxicity evoked by sodium nitroprusside and thrombin.Nitric oxide in health and disease of the nervous system.High Pressure-Induced mtDNA Alterations in Retinal Ganglion Cells and Subsequent Apoptosis.Antioxidant and bioenergetic coupling between neurons and astrocytes.Bioenergetics and redox adaptations of astrocytes to neuronal activity.Street heroin induces mitochondrial dysfunction and apoptosis in rat cortical neurons.Use of potentiometric fluorophores in the measurement of mitochondrial reactive oxygen species.Role of cyclophilin D-dependent mitochondrial permeability transition in glutamate-induced calcium deregulation and excitotoxic neuronal death.Nitric oxide evokes an adaptive response to oxidative stress by arresting respiration.VLDL Induced Modulation of Nitric Oxide Signalling and Cell Redox Homeostasis in HUVEC.Cytochrome c associated apoptosis during ATP recovery after hypoxia in neonatal rat cerebrocortical slices.Glutamate uptake inhibitor L-trans-pyrrolidine 2,4-dicarboxylate becomes neurotoxic in the presence of subthreshold concentrations of mitochondrial toxin 3-nitropropionate: involvement of mitochondrial reducing activity and ATP production.Apoptosis to necrosis switching downstream of apoptosome formation requires inhibition of both glycolysis and oxidative phosphorylation in a BCL-X(L)- and PKB/AKT-independent fashion.Increased mitochondrial respiration maintains the mitochondrial membrane potential and promotes survival of cerebellar neurons in an endogenous model of glutamate receptor activation.Neuroprotective Mechanisms of 9-Hydroxy Epinootkatol Against Glutamate-Induced Neuronal Apoptosis in Primary Neuron Culture.Nitric oxide from neuronal nitric oxide synthase sensitises neurons to hypoxia-induced death via competitive inhibition of cytochrome oxidase.The Na+/H+ exchanger-1 inhibitor cariporide prevents glutamate-induced necrotic neuronal death by inhibiting mitochondrial Ca2+ overload.PIDD-dependent activation of caspase-2-mediated mitochondrial injury in E1A-induced cellular sensitivity to macrophage nitric oxide-induced apoptosis
P2860
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P2860
A transient inhibition of mitochondrial ATP synthesis by nitric oxide synthase activation triggered apoptosis in primary cortical neurons.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年学术文章
@wuu
2001年学术文章
@zh
2001年学术文章
@zh-cn
2001年学术文章
@zh-hans
2001年学术文章
@zh-my
2001年学术文章
@zh-sg
2001年學術文章
@yue
2001年學術文章
@zh-hant
name
A transient inhibition of mito ...... s in primary cortical neurons.
@en
A transient inhibition of mito ...... s in primary cortical neurons.
@nl
type
label
A transient inhibition of mito ...... s in primary cortical neurons.
@en
A transient inhibition of mito ...... s in primary cortical neurons.
@nl
prefLabel
A transient inhibition of mito ...... s in primary cortical neurons.
@en
A transient inhibition of mito ...... s in primary cortical neurons.
@nl
P2860
P1476
A transient inhibition of mito ...... is in primary cortical neurons
@en
P2093
P2860
P304
P356
10.1046/J.1471-4159.2001.00276.X
P407
P577
2001-04-01T00:00:00Z