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Poly(ADP-ribose) polymerase-1 protects neurons against apoptosis induced by oxidative stressInhibition of mitochondrial respiration by nitric oxide rapidly stimulates cytoprotective GLUT3-mediated glucose uptake through 5'-AMP-activated protein kinasePeroxynitrite protects neurons against nitric oxide-mediated apoptosis. A key role for glucose-6-phosphate dehydrogenase activity in neuroprotectionInhibition of PTEN by peroxynitrite activates the phosphoinositide-3-kinase/Akt neuroprotective signaling pathwayCdk5 phosphorylates Cdh1 and modulates cyclin B1 stability in excitotoxicityAstrocyte NMDA receptors' activity sustains neuronal survival through a Cdk5-Nrf2 pathway.APC/CCdh1-Rock2 pathway controls dendritic integrity and memory.E3 ubiquitin ligase APC/C-Cdh1 accounts for the Warburg effect by linking glycolysis to cell proliferationRegulatory T cells modulate inflammation and reduce infarct volume in experimental brain ischaemiaGlutamate excitoxicity is the key molecular mechanism which is influenced by body temperature during the acute phase of brain stroke.The human Tp53 Arg72Pro polymorphism explains different functional prognosis in stroke.DJ1 represses glycolysis and cell proliferation by transcriptionally up-regulating Pink1.Provoking neuroprotection by peroxynitrite.Excitotoxic stimulus stabilizes PFKFB3 causing pentose-phosphate pathway to glycolysis switch and neurodegenerationMitochondrial respiratory chain and free radical generation in stroke.Cdk5-mediated inhibition of APC/C-Cdh1 switches on the cyclin D1-Cdk4-pRb pathway causing aberrant S-phase entry of postmitotic neurons.Modulation of astroglial energy metabolism by nitric oxide.Linking glycolysis with oxidative stress in neural cells: a regulatory role for nitric oxide.Complex I assembly into supercomplexes determines differential mitochondrial ROS production in neurons and astrocytes.Mitochondria and reactive oxygen and nitrogen species in neurological disorders and stroke: Therapeutic implications.Neovascularization and functional recovery after intracerebral hemorrhage is conditioned by the Tp53 Arg72Pro single-nucleotide polymorphismThe pentose-phosphate pathway in neuronal survival against nitrosative stress.Antioxidant and bioenergetic coupling between neurons and astrocytes.Genetic determinants of neuronal vulnerability to apoptosis.Brain energy metabolism in glutamate-receptor activation and excitotoxicity: role for APC/C-Cdh1 in the balance glycolysis/pentose phosphate pathway.Retinoic acid downregulates Rae1 leading to APC(Cdh1) activation and neuroblastoma SH-SY5Y differentiation.Cdh1/Hct1-APC is essential for the survival of postmitotic neurons.Interrelationships between astrocyte function, oxidative stress and antioxidant status within the central nervous system.APC/C-Cdh1 coordinates neurogenesis and cortical size during development.Bilirubin selectively inhibits cytochrome c oxidase activity and induces apoptosis in immature cortical neurons: assessment of the protective effects of glycoursodeoxycholic acid.A transient inhibition of mitochondrial ATP synthesis by nitric oxide synthase activation triggered apoptosis in primary cortical neurons.Expression of glucose transporter GLUT3 by endotoxin in cultured rat astrocytes: the role of nitric oxide.Increased mitochondrial respiration maintains the mitochondrial membrane potential and promotes survival of cerebellar neurons in an endogenous model of glutamate receptor activation.The bioenergetic and antioxidant status of neurons is controlled by continuous degradation of a key glycolytic enzyme by APC/C-Cdh1.Mitochondrial Complex I Activity is Conditioned by Supercomplex I-III2-IV Assembly in Brain Cells: Relevance for Parkinson's Disease.PINK1 deficiency sustains cell proliferation by reprogramming glucose metabolism through HIF1.Neuroprotective role of antidiabetic drug metformin against apoptotic cell death in primary cortical neurons.The MDM2-p53 pathway is involved in preconditioning-induced neuronal tolerance to ischemia.Nitric oxide switches on glycolysis through the AMP protein kinase and 6-phosphofructo-2-kinase pathway.Regulation of Bcl-xL-ATP Synthase Interaction by Mitochondrial Cyclin B1-Cyclin-Dependent Kinase-1 Determines Neuronal Survival.
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description
researcher ORCID ID = 0000-0003-0485-8904
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wetenschapper
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A Almeida
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A Almeida
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A Almeida
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P496
0000-0003-0485-8904