A novel mutation within the extracellular domain of TrkA causes constitutive receptor activation.
about
Deoxygedunin, a natural product with potent neurotrophic activity in miceTRKing down an old oncogene in a new era of targeted therapyBivalent peptidomimetic ligands of TrkC are biased agonists and selectively induce neuritogenesis or potentiate neurotrophin-3 trophic signalsA monovalent agonist of TrkA tyrosine kinase receptors can be converted into a bivalent antagonist.Small-molecule modulation of neurotrophin receptors: a strategy for the treatment of neurological disease.Alternative TrkAIII splicing: a potential regulated tumor-promoting switch and therapeutic target in neuroblastoma.An intracellular domain fragment of the p75 neurotrophin receptor (p75(NTR)) enhances tropomyosin receptor kinase A (TrkA) receptor functionTrkA receptor "hot spots" for binding of NT-3 as a heterologous ligand.Ectopic expression of TrKA in the adult rat basal ganglia induces both nerve growth factor-dependent and -independent neuronal responses.p75 Co-receptors regulate ligand-dependent and ligand-independent Trk receptor activation, in part by altering Trk docking subdomains.Dependence of neurotrophic factor activation of Trk tyrosine kinase receptors on cellular sialidase.
P2860
Q21136320-39672E4C-E142-40EC-B6FE-0E4C5484F24BQ28254287-6DF9F772-9A15-4D39-B0E4-EE9DDC41042AQ33500614-556BC97C-D698-43CA-9163-6E9916B8FF1FQ34145650-8CB3EF9E-DB1D-4181-B744-69D6691171B3Q34366768-FC394002-612B-4552-9A3D-3D4261E243E4Q36429595-3446D4FB-5ECF-47B2-9B2C-10FBFED25F5CQ36779558-F772879A-A936-4E12-81AB-4BD3DB9AF3A1Q40144725-D2E457A3-65D5-4F79-A698-92E988E58E0CQ42503430-B500EFC8-C99D-47F0-8AAF-759E6154DE91Q43653375-419E67F8-DA6A-4B70-9796-5C4FF8D03945Q48421947-945F1815-DAB7-4669-BADF-E9B3EC1C9AAF
P2860
A novel mutation within the extracellular domain of TrkA causes constitutive receptor activation.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年学术文章
@wuu
2001年学术文章
@zh
2001年学术文章
@zh-cn
2001年学术文章
@zh-hans
2001年学术文章
@zh-my
2001年学术文章
@zh-sg
2001年學術文章
@yue
2001年學術文章
@zh-hant
name
A novel mutation within the ex ...... stitutive receptor activation.
@en
A novel mutation within the ex ...... stitutive receptor activation.
@nl
type
label
A novel mutation within the ex ...... stitutive receptor activation.
@en
A novel mutation within the ex ...... stitutive receptor activation.
@nl
prefLabel
A novel mutation within the ex ...... stitutive receptor activation.
@en
A novel mutation within the ex ...... stitutive receptor activation.
@nl
P2093
P2860
P50
P356
P1433
P1476
A novel mutation within the ex ...... stitutive receptor activation.
@en
P2093
Hempstead BI
Martín-Zanca D
P2860
P2888
P304
P356
10.1038/SJ.ONC.1204215
P407
P577
2001-03-01T00:00:00Z
P5875
P6179
1033459833