Germline mutations of the gene encoding bone morphogenetic protein receptor 1A in juvenile polyposis.
about
Multiple common susceptibility variants near BMP pathway loci GREM1, BMP4, and BMP2 explain part of the missing heritability of colorectal cancerMutations in bone morphogenetic protein receptor 1B cause brachydactyly type A2Germline mutations in SMAD4 disrupt bone morphogenetic protein signalingProtean PTEN: form and functionHereditary haemorrhagic telangiectasia: current views on genetics and mechanisms of diseaseHigh proportion of large genomic deletions and a genotype phenotype update in 80 unrelated families with juvenile polyposis syndromeA census of human cancer genesHamartomatous polyposis syndromesBMP receptor signaling is required for postnatal maintenance of articular cartilageThe Inositide Signaling Pathway As a Target for Treating Gastric Cancer and Colorectal CancerTargeting BMP signalling in cardiovascular disease and anaemiaTGF-β/BMP signaling and other molecular events: regulation of osteoblastogenesis and bone formationTGF-β and BMP signaling in osteoblast differentiation and bone formationDefining hierarchies of stemness in the intestine: evidence from biomarkers and regulatory pathwaysPTEN-deficient intestinal stem cells initiate intestinal polyposis.Structure analysis of bone morphogenetic protein-2 type I receptor complexes reveals a mechanism of receptor inactivation in juvenile polyposis syndromeActivin receptor-like kinases: a diverse family playing an important role in cancerThe genetic heterogeneity of colorectal cancer predisposition - guidelines for gene discoveryGenetic Variants That Predispose to DNA Double-Strand Breaks in Lymphocytes From a Subset of Patients With Familial Colorectal CarcinomasTGF-β family signaling in stem cellsIncomplete penetrance and phenotypic variability characterize Gdf6-attributable oculo-skeletal phenotypesDevelopment and differentiation of the intestinal epitheliumGenomic fossils as a snapshot of the human transcriptomeMeta-analysis of genome-wide association data identifies four new susceptibility loci for colorectal cancerPatterns of somatic mutation in human cancer genomesGranulosa cell-expressed BMPR1A and BMPR1B have unique functions in regulating fertility but act redundantly to suppress ovarian tumor development.Genetic variation in bone morphogenetic protein and colon and rectal cancer.Canonical Wnt signals combined with suppressed TGFβ/BMP pathways promote renewal of the native human colonic epithelium.BMP-specific SMADs function as novel repressors of PDGFA and modulate its expression in ovarian granulosa cells and tumors.A rapid and sensitive bioassay to measure bone morphogenetic protein activity.Controlling destiny through chemistry: small-molecule regulators of cell fate.Gastrointestinal tract cancers: Genetics, heritability and germ line mutationsGenetic testing for hereditary colorectal cancer.Medical applications of transforming growth factor-betaConstitutive activation of BMP signalling abrogates experimental metastasis of OVCA429 cells via reduced cell adhesionSomatic mutation profiles of MSI and MSS colorectal cancer identified by whole exome next generation sequencing and bioinformatics analysis.Differential expressions of BMPR1α, ACTN4α and FABP7 in Hirschsprung disease.Comprehensive assessment of variation at the transforming growth factor beta type 1 receptor locus and colorectal cancer predisposition.Histologic variations in juvenile polyp phenotype correlate with genetic defect underlying juvenile polyposisEpimorphin deletion protects mice from inflammation-induced colon carcinogenesis and alters stem cell niche myofibroblast secretion.
P2860
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P2860
Germline mutations of the gene encoding bone morphogenetic protein receptor 1A in juvenile polyposis.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年学术文章
@wuu
2001年学术文章
@zh-cn
2001年学术文章
@zh-hans
2001年学术文章
@zh-my
2001年学术文章
@zh-sg
2001年學術文章
@yue
2001年學術文章
@zh
2001年學術文章
@zh-hant
name
Germline mutations of the gene ...... ptor 1A in juvenile polyposis.
@en
Germline mutations of the gene ...... ptor 1A in juvenile polyposis.
@nl
type
label
Germline mutations of the gene ...... ptor 1A in juvenile polyposis.
@en
Germline mutations of the gene ...... ptor 1A in juvenile polyposis.
@nl
prefLabel
Germline mutations of the gene ...... ptor 1A in juvenile polyposis.
@en
Germline mutations of the gene ...... ptor 1A in juvenile polyposis.
@nl
P2093
P356
P1433
P1476
Germline mutations of the gene ...... eptor 1A in juvenile polyposis
@en
P2093
B Vogelstein
F A Mitros
G M Petersen
G Traverso
M E Anderson
P304
P356
10.1038/88919
P407
P577
2001-06-01T00:00:00Z
P6179
1022573828