Systematic optimization of expression and refolding of the Plasmodium falciparum cysteine protease falcipain-2.
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Expression and biochemical characterization of the Plasmodium falciparum DNA repair enzyme, flap endonuclease-1 (PfFEN-1)Expression and characterization of the Plasmodium falciparum haemoglobinase falcipain-3Biochemical properties of a novel cysteine protease of Plasmodium vivax, vivapain-4Blocking Plasmodium falciparum development via dual inhibition of hemoglobin degradation and the ubiquitin proteasome system by MG132Scalable Production of Recombinant Membrane Active Peptides and Its Potential as a Complementary Adjunct to Conventional ChemotherapeuticsStructural basis for unique mechanisms of folding and hemoglobin binding by a malarial proteaseDevelopment and characterization of an automated high throughput screening method for optimization of protein refolding processes.A novel Entamoeba histolytica cysteine proteinase, EhCP4, is key for invasive amebiasis and a therapeutic target.Critical role of amino acid 23 in mediating activity and specificity of vinckepain-2, a papain-family cysteine protease of rodent malaria parasites.Use of recombinant Entamoeba histolytica cysteine proteinase 1 to identify a potent inhibitor of amebic invasion in a human colonic model.Hemoglobin cleavage site-specificity of the Plasmodium falciparum cysteine proteases falcipain-2 and falcipain-3.Identification of Tight-Binding Plasmepsin II and Falcipain 2 Inhibitors in Aqueous Extracts of Marine Invertebrates by the Combination of Enzymatic and Interaction-Based Assays.The Plasmodium falciparum cysteine protease falcipain-2 captures its substrate, hemoglobin, via a unique motif.The cysteine protease α-clostripain is not essential for the pathogenesis of Clostridium perfringens-mediated myonecrosis.Antimalarial activities of novel synthetic cysteine protease inhibitors.Bovipain-2, the falcipain-2 ortholog, is expressed in intraerythrocytic stages of the tick-transmitted hemoparasite Babesia bovisInhibition of dengue NS2B-NS3 protease and viral replication in Vero cells by recombinant retrocyclin-1Fusion of protegrin-1 and plectasin to MAP30 shows significant inhibition activity against dengue virus replicationSynthetic compounds from an in house library as inhibitors of falcipain-2 from Plasmodium falciparum.Effect of codon optimization on expression levels of a functionally folded malaria vaccine candidate in prokaryotic and eukaryotic expression systemsHigh-throughput automated refolding screening of inclusion bodies.Efficient expression systems for cysteine proteases of malaria parasites: too good to be true?Heterologous expression of plasmodial proteins for structural studies and functional annotation.Trafficked Proteins-Druggable in Plasmodium falciparum?The transcriptional co-activator MBF1c is a key regulator of thermotolerance in Arabidopsis thaliana.Approaches for the generation of active papain-like cysteine proteases from inclusion bodies of Escherichia coli.Antiviral cationic peptides as a strategy for innovation in global health therapeutics for dengue virus: high yield production of the biologically active recombinant plectasin peptide.Efficient co-expression of a recombinant staphopain A and its inhibitor staphostatin A in Escherichia coli.Identification and biochemical characterization of vivapains, cysteine proteases of the malaria parasite Plasmodium vivax.Synthesis and molecular modeling studies of derivatives of a highly potent peptidomimetic vinyl ester as falcipain-2 inhibitors.Substrate mapping and inhibitor profiling of falcipain-2, falcipain-3 and berghepain-2: implications for peptidase anti-malarial drug discovery.Folding of the Plasmodium falciparum cysteine protease falcipain-2 is mediated by a chaperone-like peptide and not the prodomain.Ricinosomes predict programmed cell death leading to anther dehiscence in tomato.Independent intramolecular mediators of folding, activity, and inhibition for the Plasmodium falciparum cysteine protease falcipain-2.Synthesis and antiplasmodial activity of a cysteine protease-inhibiting biotinylated aziridine-2,3-dicarboxylate.Structural and functional characterization of Falcipain-2, a hemoglobinase from the malarial parasite Plasmodium falciparum.
P2860
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P2860
Systematic optimization of expression and refolding of the Plasmodium falciparum cysteine protease falcipain-2.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年学术文章
@wuu
2001年学术文章
@zh-cn
2001年学术文章
@zh-hans
2001年学术文章
@zh-my
2001年学术文章
@zh-sg
2001年學術文章
@yue
2001年學術文章
@zh
2001年學術文章
@zh-hant
name
Systematic optimization of exp ...... cysteine protease falcipain-2.
@en
Systematic optimization of exp ...... cysteine protease falcipain-2.
@nl
type
label
Systematic optimization of exp ...... cysteine protease falcipain-2.
@en
Systematic optimization of exp ...... cysteine protease falcipain-2.
@nl
prefLabel
Systematic optimization of exp ...... cysteine protease falcipain-2.
@en
Systematic optimization of exp ...... cysteine protease falcipain-2.
@nl
P2093
P356
P1476
Systematic optimization of exp ...... cysteine protease falcipain-2.
@en
P2093
Rosenthal PJ
Sijwali PS
P304
P356
10.1006/PREP.2001.1416
P577
2001-06-01T00:00:00Z