Reduced amide bond peptidomimetics. (4S)-N-(4-amino-5-[aminoakyl]aminopentyl)-N'-nitroguanidines, potent and highly selective inhibitors of neuronal nitric oxide synthase.
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Role of zinc in isoform-selective inhibitor binding to neuronal nitric oxide synthaseStructural basis for dipeptide amide isoform-selective inhibition of neuronal nitric oxide synthaseStructure-Based Design and Synthesis of N ω -Nitro- l -Arginine-Containing Peptidomimetics as Selective Inhibitors of Neuronal Nitric Oxide Synthase. Displacement of the Heme Structural WaterMinimal Pharmacophoric Elements and Fragment Hopping, an Approach Directed at Molecular Diversity and Isozyme Selectivity. Design of Selective Neuronal Nitric Oxide Synthase InhibitorsCrystal Structures of Constitutive Nitric Oxide Synthases in Complex with De Novo Designed Inhibitors †Unexpected Binding Modes of Nitric Oxide Synthase Inhibitors Effective in the Prevention of a Cerebral Palsy Phenotype in an Animal ModelExploration of the Active Site of Neuronal Nitric Oxide Synthase by the Design and Synthesis of Pyrrolidinomethyl 2-Aminopyridine DerivativesNeuronal nitric oxide inhibits intestinal smooth muscle growthTraumatic brain injury disrupts cerebrovascular tone through endothelial inducible nitric oxide synthase expression and nitric oxide gain of functionCharacteristics and function of cardiac mitochondrial nitric oxide synthase.Development of nitric oxide synthase inhibitors for neurodegeneration and neuropathic pain.Nitric oxide synthases activation and inhibition by metallacarborane-cluster-based isoform-specific affectors.Mechanistic studies of inactivation of inducible nitric oxide synthase by amidinesIntracellular nitric oxide mediates neuroproliferative effect of neuropeptide y on postnatal hippocampal precursor cells.Hydroxyethylene isosteres of selective neuronal nitric oxide synthase inhibitorsTarget- and mechanism-based therapeutics for neurodegenerative diseases: strength in numbersDiscovery of highly potent and selective inhibitors of neuronal nitric oxide synthase by fragment hopping.A cellular model for screening neuronal nitric oxide synthase inhibitorsDesign of selective neuronal nitric oxide synthase inhibitors for the prevention and treatment of neurodegenerative diseases.Nitric oxide as key mediator of neuron-to-neuron and endothelia-to-glia communication involved in the neuroendocrine control of reproduction.Novel nitric oxide synthase inhibitors: a patent review.Arginine-based inhibitors of nitric oxide synthase: therapeutic potential and challenges.Induction and expression of GluA1 (GluR-A)-independent LTP in the hippocampus.The effect of the aquatic contaminants bisphenol-A and PCB-95 on the zebrafish lateral line.Differential effects of nitric oxide synthase inhibitors on endothelium-dependent and nitrergic nerve-mediated vasodilatation in the bovine ciliary artery.Structural basis for isoform-selective inhibition in nitric oxide synthase.
P2860
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P2860
Reduced amide bond peptidomimetics. (4S)-N-(4-amino-5-[aminoakyl]aminopentyl)-N'-nitroguanidines, potent and highly selective inhibitors of neuronal nitric oxide synthase.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年学术文章
@wuu
2001年学术文章
@zh
2001年学术文章
@zh-cn
2001年学术文章
@zh-hans
2001年学术文章
@zh-my
2001年学术文章
@zh-sg
2001年學術文章
@yue
2001年學術文章
@zh-hant
name
Reduced amide bond peptidomime ...... euronal nitric oxide synthase.
@en
Reduced amide bond peptidomime ...... euronal nitric oxide synthase.
@nl
type
label
Reduced amide bond peptidomime ...... euronal nitric oxide synthase.
@en
Reduced amide bond peptidomime ...... euronal nitric oxide synthase.
@nl
prefLabel
Reduced amide bond peptidomime ...... euronal nitric oxide synthase.
@en
Reduced amide bond peptidomime ...... euronal nitric oxide synthase.
@nl
P2093
P356
P1476
Reduced amide bond peptidomime ...... euronal nitric oxide synthase.
@en
P2093
P304
P356
10.1021/JM0101491
P407
P577
2001-08-01T00:00:00Z