Structure prediction and active site analysis of the metal binding determinants in gamma -glutamylcysteine synthetase.
about
Structure, function, and post-translational regulation of the catalytic and modifier subunits of glutamate cysteine ligaseManipulation of cellular GSH biosynthetic capacity via TAT-mediated protein transduction of wild-type or a dominant-negative mutant of glutamate cysteine ligase alters cell sensitivity to oxidant-induced cytotoxicityLateral gene transfer and parallel evolution in the history of glutathione biosynthesis genesMechanistic Details of Glutathione Biosynthesis Revealed by Crystal Structures of Saccharomyces cerevisiae Glutamate Cysteine LigaseStructural Basis for Feedback and Pharmacological Inhibition of Saccharomyces cerevisiae Glutamate Cysteine LigaseGlutathione synthetase homologs encode alpha-L-glutamate ligases for methanogenic coenzyme F420 and tetrahydrosarcinapterin biosynthesesPrediction of the functional class of metal-binding proteins from sequence derived physicochemical properties by support vector machine approachUnraveling the biochemistry and provenance of pupylation: a prokaryotic analog of ubiquitinationAmidoligases with ATP-grasp, glutamine synthetase-like and acetyltransferase-like domains: synthesis of novel metabolites and peptide modifications of proteinsA multidomain fusion protein in Listeria monocytogenes catalyzes the two primary activities for glutathione biosynthesisStructure of Mycobacterium tuberculosis glutamine synthetase in complex with a transition-state mimic provides functional insights.Structural basis for the redox control of plant glutamate cysteine ligase.Using protein design for homology detection and active site searchesGlutathione, photosynthesis and the redox regulation of stress-responsive gene expression.Genetic determination of essential residues of the Vibrio cholerae actin cross-linking domain reveals functional similarity with glutamine synthetases.Crystal structure of gamma-glutamylcysteine synthetase: insights into the mechanism of catalysis by a key enzyme for glutathione homeostasis.DapE can function as an aspartyl peptidase in the presence of Mn2+.Biochemical and biophysical characterization of Leishmania donovani gamma-glutamylcysteine synthetaseEscherichia coli gamma-glutamylcysteine synthetase. Two active site metal ions affect substrate and inhibitor binding.Depupylase Dop Requires Inorganic Phosphate in the Active Site for Catalysis.The redox switch of gamma-glutamylcysteine ligase via a reversible monomer-dimer transition is a mechanism unique to plants.Characterization of a cold-adapted glutathione synthetase from the psychrophile Pseudoalteromonas haloplanktis.Molecular modeling of Trypanosoma cruzi glutamate cysteine ligase and investigation of its interactions with glutathione
P2860
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P2860
Structure prediction and active site analysis of the metal binding determinants in gamma -glutamylcysteine synthetase.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年学术文章
@wuu
2001年学术文章
@zh
2001年学术文章
@zh-cn
2001年学术文章
@zh-hans
2001年学术文章
@zh-my
2001年学术文章
@zh-sg
2001年學術文章
@yue
2001年學術文章
@zh-hant
name
Structure prediction and activ ...... -glutamylcysteine synthetase.
@en
Structure prediction and activ ...... -glutamylcysteine synthetase.
@nl
type
label
Structure prediction and activ ...... -glutamylcysteine synthetase.
@en
Structure prediction and activ ...... -glutamylcysteine synthetase.
@nl
prefLabel
Structure prediction and activ ...... -glutamylcysteine synthetase.
@en
Structure prediction and activ ...... -glutamylcysteine synthetase.
@nl
P2093
P2860
P356
P1476
Structure prediction and activ ...... -glutamylcysteine synthetase.
@en
P2093
Grishin VN
Phillips MA
Pitcher LA
P2860
P304
42099-42107
P356
10.1074/JBC.M104672200
P407
P577
2001-08-29T00:00:00Z