Structural model for the reaction mechanism of glutamine synthetase, based on five crystal structures of enzyme-substrate complexes
about
Discovery of the ammonium substrate site on glutamine synthetase, a third cation binding siteGlutamine synthetase in Medicago truncatula, unveiling new secrets of a very old enzymeMethionine oxidation and reduction in proteinsProkaryotic ubiquitin-like protein modificationLengsin Is a Survivor of an Ancient Family of Class I Glutamine Synthetases Re-engineered by Evolution for a Role in the Vertebrate LensMechanisms of Activation of Phosphoenolpyruvate Carboxykinase from Escherichia coli by Ca2+ and of Desensitization by TrypsinStructural Basis for Feedback and Pharmacological Inhibition of Saccharomyces cerevisiae Glutamate Cysteine LigaseTrisubstituted Imidazoles as Mycobacterium tuberculosis Glutamine Synthetase InhibitorsStructures of the Bacillus subtilis Glutamine Synthetase Dodecamer Reveal Large Intersubunit Catalytic Conformational Changes Linked to a Unique Feedback Inhibition MechanismStructural Basis for the Active Site Inhibition Mechanism of Human Kidney-Type Glutaminase (KGA)The structures of cytosolic and plastid-located glutamine synthetases fromMedicago truncatulareveal a common and dynamic architectureSnapshot of a phosphorylated substrate intermediate by kinetic crystallographyIn Salmonella enterica, the Gcn5-related acetyltransferase MddA (formerly YncA) acetylates methionine sulfoximine and methionine sulfone, blocking their toxic effectsNitrogen assimilation in Escherichia coli: putting molecular data into a systems perspectiveFunctional roles of the conserved Glu304 loop of Bacillus subtilis glutamine synthetaseAsparagine synthetase chemotherapy.Mycobacterial ubiquitin-like protein ligase PafA follows a two-step reaction pathway with a phosphorylated pup intermediate.An inhibitor of human asparagine synthetase suppresses proliferation of an L-asparaginase-resistant leukemia cell line.Feedback-resistant mutations in Bacillus subtilis glutamine synthetase are clustered in the active site.A sensing role of the glutamine synthetase in the nitrogen regulation network in Fusarium fujikuroiStructures of regulatory machinery reveal novel molecular mechanisms controlling B. subtilis nitrogen homeostasis.Molecular Mechanisms of Glutamine Synthetase Mutations that Lead to Clinically Relevant Pathologies.Identification of the enzyme responsible for N-acetylation of norfloxacin by Microbacterium sp. Strain 4N2-2.The Genomes of Three Uneven Siblings: Footprints of the Lifestyles of Three Trichoderma Species.Novel trans-Acting Bacillus subtilis glnA mutations that derepress glnRA expression.Focus on phosphoaspartate and phosphoglutamate.Mutational analysis of Asp51 of Anabaena azollae glutamine synthetase. D51E mutation confers resistance to the active site inhibitors L-methionine-DL-sulfoximine and phosphinothricin.The Molecular Basis of TnrA Control by Glutamine Synthetase in Bacillus subtilis.Glutamine Synthetase: Role in Neurological Disorders.The Glutamate-Glutamine Cycle in Epilepsy.Biochemical and mutational analysis of glutamine synthetase type III from the rumen anaerobe Ruminococcus albus 8.Phenotypic changes resulting from distinct point mutations in the Azospirillum brasilense glnA gene, encoding glutamine synthetaseStructure prediction and active site analysis of the metal binding determinants in gamma -glutamylcysteine synthetase.Escherichia coli gamma-glutamylcysteine synthetase. Two active site metal ions affect substrate and inhibitor binding.Mutations in Bacillus subtilis glutamine synthetase that block its interaction with transcription factor TnrA.Identification of three key active site residues in the C-terminal domain of human recombinant folylpoly-gamma-glutamate synthetase by site-directed mutagenesis.A feedback-resistant mutant of Bacillus subtilis glutamine synthetase with pleiotropic defects in nitrogen-regulated gene expression.Probing the origins of glutathione biosynthesis through biochemical analysis of glutamate-cysteine ligase and glutathione synthetase from a model photosynthetic prokaryote.Mechanistic Basis for ATP-Dependent Inhibition of Glutamine Synthetase by Tabtoxinine-β-lactam.Chemoselective generation of acyl phosphates, acylium ion equivalents, from carboxylic acids and an organophosphate ester in the presence of a Brønsted acid.
P2860
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P2860
Structural model for the reaction mechanism of glutamine synthetase, based on five crystal structures of enzyme-substrate complexes
description
1994 nî lūn-bûn
@nan
1994 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
1994 թվականի հունվարին հրատարակված գիտական հոդված
@hy
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
name
Structural model for the react ...... of enzyme-substrate complexes
@ast
Structural model for the react ...... of enzyme-substrate complexes
@en
Structural model for the react ...... of enzyme-substrate complexes
@nl
type
label
Structural model for the react ...... of enzyme-substrate complexes
@ast
Structural model for the react ...... of enzyme-substrate complexes
@en
Structural model for the react ...... of enzyme-substrate complexes
@nl
prefLabel
Structural model for the react ...... of enzyme-substrate complexes
@ast
Structural model for the react ...... of enzyme-substrate complexes
@en
Structural model for the react ...... of enzyme-substrate complexes
@nl
P356
P1433
P1476
Structural model for the react ...... of enzyme-substrate complexes
@en
P2093
P304
P356
10.1021/BI00169A007
P407
P577
1994-01-25T00:00:00Z