ErbB2-overexpressing human mammary carcinoma cells display an increased requirement for the phosphatidylinositol 3-kinase signaling pathway in anchorage-independent growth.
about
Trastuzumab, an appropriate first-line single-agent therapy for HER2-overexpressing metastatic breast cancerFunctional interaction between mouse erbB3 and wild-type rat c-neu in transgenic mouse mammary tumor cells.Celecoxib analogues disrupt Akt signaling, which is commonly activated in primary breast tumoursGenes affecting the cell cycle, growth, maintenance, and drug sensitivity are preferentially regulated by anti-HER2 antibody through phosphatidylinositol 3-kinase-AKT signalingThe mitogenic action of insulin-like growth factor I in normal human mammary epithelial cells requires the epidermal growth factor receptor tyrosine kinase.AKT inhibition relieves feedback suppression of receptor tyrosine kinase expression and activityChronic morphine treatment attenuates cell growth of human BT474 breast cancer cells by rearrangement of the ErbB signalling network.Inhibitors of HSP90 block p95-HER2 signaling in Trastuzumab-resistant tumors and suppress their growthHRG-β1-driven ErbB3 signaling induces epithelial-mesenchymal transition in breast cancer cells.Dysregulation of HER2/HER3 signaling axis in Epstein-Barr virus-infected breast carcinoma cells.Growth factor signaling induces metastasis genes in transformed cells: molecular connection between Akt kinase and osteopontin in breast cancerRapamycin inhibits multiple stages of c-Neu/ErbB2 induced tumor progression in a transgenic mouse model of HER2-positive breast cancerFatty acid synthase regulates estrogen receptor-α signaling in breast cancer cells.LOXL2 induces aberrant acinar morphogenesis via ErbB2 signaling.Design optimization and characterization of Her2/neu-targeted immunotoxins: comparative in vitro and in vivo efficacy studiesGamma-tocotrienol inhibits neoplastic mammary epithelial cell proliferation by decreasing Akt and nuclear factor kappaB activity.Degradation of HER2/neu by apigenin induces apoptosis through cytochrome c release and caspase-3 activation in HER2/neu-overexpressing breast cancer cells.Improved Aptamers for the Diagnosis and Potential Treatment of HER2-Positive Cancer.Loss of PTEN/MMAC1/TEP in EGF receptor-expressing tumor cells counteracts the antitumor action of EGFR tyrosine kinase inhibitors.HER2/PI-3K/Akt activation leads to a multidrug resistance in human breast adenocarcinoma cells.AMPK-Akt Double-Negative Feedback Loop in Breast Cancer Cells Regulates Their Adaptation to Matrix Deprivation.Effects of ErbB-2 overexpression on mitogenic signalling and cell cycle progression in human breast luminal epithelial cells.Meta-analysis reveals no significant correlation between breast cancer survival and ErbB3 expression.
P2860
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P2860
ErbB2-overexpressing human mammary carcinoma cells display an increased requirement for the phosphatidylinositol 3-kinase signaling pathway in anchorage-independent growth.
description
2001 nî lūn-bûn
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2001年の論文
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2001年学术文章
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2001年学术文章
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2001年学术文章
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2001年学术文章
@zh-hans
2001年学术文章
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2001年学术文章
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2001年學術文章
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2001年學術文章
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name
ErbB2-overexpressing human mam ...... anchorage-independent growth.
@en
ErbB2-overexpressing human mam ...... anchorage-independent growth.
@nl
type
label
ErbB2-overexpressing human mam ...... anchorage-independent growth.
@en
ErbB2-overexpressing human mam ...... anchorage-independent growth.
@nl
prefLabel
ErbB2-overexpressing human mam ...... anchorage-independent growth.
@en
ErbB2-overexpressing human mam ...... anchorage-independent growth.
@nl
P2093
P2860
P356
P1433
P1476
ErbB2-overexpressing human mam ...... anchorage-independent growth.
@en
P2093
P2860
P2888
P304
P356
10.1038/SJ.ONC.1204964
P407
P577
2001-11-01T00:00:00Z
P5875
P6179
1015837117