Specific cGMP binding by the cGMP binding domains of cGMP-binding cGMP specific phosphodiesterase.
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The two GAF domains in phosphodiesterase 2A have distinct roles in dimerization and in cGMP bindingConformation Changes, N-terminal Involvement, and cGMP Signal Relay in the Phosphodiesterase-5 GAF DomainMolecular determinants for cyclic nucleotide binding to the regulatory domains of phosphodiesterase 2APivotal effects of phosphodiesterase inhibitors on myocyte contractility and viability in normal and ischemic hearts.Crystal structure of the tandem GAF domains from a cyanobacterial adenylyl cyclase: modes of ligand binding and dimerizationcGMP-dependent protein kinases and cGMP phosphodiesterases in nitric oxide and cGMP action.Mechanisms of action of PDE5 inhibition in erectile dysfunction.PDE5 inhibitors as therapeutics for heart disease, diabetes and cancerDirect activation of PDE5 by cGMP: long-term effects within NO/cGMP signalingRole of phosphodiesterase 5 in synaptic plasticity and memoryRapid nitric oxide-induced desensitization of the cGMP response is caused by increased activity of phosphodiesterase type 5 paralleled by phosphorylation of the enzyme.Phosphorylation of isolated human phosphodiesterase-5 regulatory domain induces an apparent conformational change and increases cGMP binding affinity.Modeling and mutational analysis of the GAF domain of the cGMP-binding, cGMP-specific phosphodiesterase, PDE5.Molecular determinants of cGMP binding to chicken cone photoreceptor phosphodiesterase.Cyclic GMP-specific phosphodiesterase 5 regulates growth and apoptosis in pulmonary endothelial cells.3',5'-cIMP as Potential Second Messenger in the Vascular Wall.
P2860
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P2860
Specific cGMP binding by the cGMP binding domains of cGMP-binding cGMP specific phosphodiesterase.
description
2002 nî lūn-bûn
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2002年の論文
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2002年学术文章
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2002年学术文章
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2002年学术文章
@zh-cn
2002年学术文章
@zh-hans
2002年学术文章
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2002年学术文章
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2002年學術文章
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name
Specific cGMP binding by the c ...... MP specific phosphodiesterase.
@en
Specific cGMP binding by the c ...... MP specific phosphodiesterase.
@nl
type
label
Specific cGMP binding by the c ...... MP specific phosphodiesterase.
@en
Specific cGMP binding by the c ...... MP specific phosphodiesterase.
@nl
prefLabel
Specific cGMP binding by the c ...... MP specific phosphodiesterase.
@en
Specific cGMP binding by the c ...... MP specific phosphodiesterase.
@nl
P2093
P1433
P1476
Specific cGMP binding by the c ...... MP specific phosphodiesterase.
@en
P2093
Rifat Pamukcu
Tashandra Underwood
W Joseph Thompson
P356
10.1016/S0898-6568(01)00216-9
P577
2002-01-01T00:00:00Z