Mammalian target of rapamycin (mTOR): pro- and anti-apoptotic.
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Wip1 phosphatase: between p53 and MAPK kinases pathwaysmTOR/p70S6k signalling alteration by Abeta exposure as well as in APP-PS1 transgenic models and in patients with Alzheimer's diseaseThe physiology and pathophysiology of rapamycin resistance: implications for cancerSalinomycin induces autophagy in colon and breast cancer cells with concomitant generation of reactive oxygen speciesThe mammalian target of rapamycin signaling pathway mediates epileptogenesis in a model of temporal lobe epilepsymiR-199a impairs autophagy and induces cardiac hypertrophy through mTOR activationTemsirolimus in combination with carboplatin and paclitaxel in patients with advanced solid tumors: a NCIC-CTG, phase I, open-label dose-escalation study (IND 179).Overexpression of Exosomal Cardioprotective miRNAs Mitigates Hypoxia-Induced H9c2 Cells Apoptosis.Developing Antiepileptogenic Drugs for Acquired Epilepsy: Targeting the Mammalian Target of Rapamycin (mTOR) Pathway.Dysregulation of apoptotic signaling in cancer: molecular mechanisms and therapeutic opportunitiesRapamycin is active against B-precursor leukemia in vitro and in vivo, an effect that is modulated by IL-7-mediated signaling.Mammalian target of rapamycin (mTOR) inhibition as a potential antiepileptogenic therapy: From tuberous sclerosis to common acquired epilepsiesEffects of mTOR inhibitor everolimus (RAD001) on bladder cancer cells.Role of mTOR, Bad, and Survivin in RasGAP Fragment N-Mediated Cell ProtectionTherapeutic role of mammalian target of rapamycin (mTOR) inhibition in preventing epileptogenesis.The cytoplasmic tail of FPC antagonizes the full-length protein in the regulation of mTOR pathwaybFGF regulates autophagy and ubiquitinated protein accumulation induced by myocardial ischemia/reperfusion via the activation of the PI3K/Akt/mTOR pathway.Induction of autophagy in rats upon overexpression of wild-type and mutant optineurin gene.Ethambutol induces impaired autophagic flux and apoptosis in the rat retina.A synthetic-lethality RNAi screen reveals an ERK-mTOR co-targeting pro-apoptotic switch in PIK3CA+ oral cancersCell death signaling and anticancer therapyCoupled down-regulation of mTOR and telomerase activity during fluorouracil-induced apoptosis of hepatocarcinoma cellsN-n-butyl haloperidol iodide protects cardiomyocytes against hypoxia/reoxygenation injury by inhibiting autophagy.Propofol Suppressed Hypoxia/Reoxygenation-Induced Apoptosis in HBVSMC by Regulation of the Expression of Bcl-2, Bax, Caspase3, Kir6.1, and p-JNKGOLPH3 is a potential therapeutic target and a prognostic indicator of poor survival in bladder cancer treated by cystectomy.Elevated phosphorylation and activation of PDK-1/AKT pathway in human breast cancerSestrin2 integrates Akt and mTOR signaling to protect cells against energetic stress-induced deathTAK1 regulates autophagic cell death by suppressing the phosphorylation of p70 S6 kinase 1.PRAS40 deregulates apoptosis in Ewing sarcoma family tumors by enhancing the insulin receptor/Akt and mTOR signaling pathwaysDefects in skin gamma delta T cell function contribute to delayed wound repair in rapamycin-treated miceJujuboside A Protects H9C2 Cells from Isoproterenol-Induced Injury via Activating PI3K/Akt/mTOR Signaling PathwayRapamycin Influences the Efficiency of In vitro Fertilization and Development in the Mouse: A Role for Autophagic ActivationmicroRNA-199a is able to reverse cisplatin resistance in human ovarian cancer cells through the inhibition of mammalian target of rapamycin.Danshensu alleviates cardiac ischaemia/reperfusion injury by inhibiting autophagy and apoptosis via activation of mTOR signalling.Upstream and Downstream Co-inhibition of Mitogen-Activated Protein Kinase and PI3K/Akt/mTOR Pathways in Pancreatic Ductal Adenocarcinoma.Cross-species withdrawal of MCL1 facilitates postpartum uterine involution in both the mouse and baboon.Novel functional roles of caspase-related genes in the regulation of apoptosis and autophagy.Rapamycin Prolongs the Survival of Corneal Epithelial Cells in Culture.Regulation of cell death and epileptogenesis by the mammalian target of rapamycin (mTOR): a double-edged sword?Immune dysfunction in autism: a pathway to treatment.
P2860
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P2860
Mammalian target of rapamycin (mTOR): pro- and anti-apoptotic.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年学术文章
@wuu
2002年学术文章
@zh
2002年学术文章
@zh-cn
2002年学术文章
@zh-hans
2002年学术文章
@zh-my
2002年学术文章
@zh-sg
2002年學術文章
@yue
2002年學術文章
@zh-hant
name
Mammalian target of rapamycin (mTOR): pro- and anti-apoptotic.
@en
type
label
Mammalian target of rapamycin (mTOR): pro- and anti-apoptotic.
@en
prefLabel
Mammalian target of rapamycin (mTOR): pro- and anti-apoptotic.
@en
P356
P1476
Mammalian target of rapamycin (mTOR): pro- and anti-apoptotic.
@en
P2093
P304
P356
10.1038/SJ/CDD/4400978
P577
2002-02-01T00:00:00Z