Repair of clustered DNA lesions. Sequence-specific inhibition of long-patch base excision repair be 8-oxoguanine.
about
Efficient formation of the tandem thymine glycol/8-oxo-7,8-dihydroguanine lesion in isolated DNA and the mutagenic and cytotoxic properties of the tandem lesions in Escherichia coli cells.Apex1 can cleave complex clustered DNA lesions in cells.DNA-PKcs deficiency leads to persistence of oxidatively induced clustered DNA lesions in human tumor cells.Irreparable complex DNA double-strand breaks induce chromosome breakage in organotypic three-dimensional human lung epithelial cell cultureThe checkpoint clamp, Rad9-Rad1-Hus1 complex, preferentially stimulates the activity of apurinic/apyrimidinic endonuclease 1 and DNA polymerase beta in long patch base excision repairDNA repair of clustered lesions in mammalian cells: involvement of non-homologous end-joining.Synthesis and thermodynamic studies of oligodeoxyribonucleotides containing tandem lesions of thymidine glycol and 8-oxo-2'-deoxyguanosineThe formation of double-strand breaks at multiply damaged sites is driven by the kinetics of excision/incision at base damage in eukaryotic cells.The yield, processing, and biological consequences of clustered DNA damage induced by ionizing radiation.In vitro replication and repair studies of tandem lesions containing neighboring thymidine glycol and 8-oxo-7,8-dihydro-2'-deoxyguanosineQuantification of 8-oxodGuo lesions in double-stranded DNA using a photoelectrochemical DNA sensor.Hierarchy of lesion processing governs the repair, double-strand break formation and mutability of three-lesion clustered DNA damage.Enhanced mutagenic potential of 8-oxo-7,8-dihydroguanine when present within a clustered DNA damage siteMode of inhibition of short-patch base excision repair by thymine glycol within clustered DNA lesions.
P2860
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P2860
Repair of clustered DNA lesions. Sequence-specific inhibition of long-patch base excision repair be 8-oxoguanine.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年学术文章
@wuu
2002年学术文章
@zh-cn
2002年学术文章
@zh-hans
2002年学术文章
@zh-my
2002年学术文章
@zh-sg
2002年學術文章
@yue
2002年學術文章
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2002年學術文章
@zh-hant
name
Repair of clustered DNA lesion ...... cision repair be 8-oxoguanine.
@en
Repair of clustered DNA lesion ...... cision repair be 8-oxoguanine.
@nl
type
label
Repair of clustered DNA lesion ...... cision repair be 8-oxoguanine.
@en
Repair of clustered DNA lesion ...... cision repair be 8-oxoguanine.
@nl
prefLabel
Repair of clustered DNA lesion ...... cision repair be 8-oxoguanine.
@en
Repair of clustered DNA lesion ...... cision repair be 8-oxoguanine.
@nl
P2093
P2860
P356
P1476
Repair of clustered DNA lesion ...... cision repair be 8-oxoguanine.
@en
P2093
Grigory L Dianov
Helen Budworth
Irina I Dianova
Vladimir N Podust
P2860
P304
21300-21305
P356
10.1074/JBC.M201918200
P407
P577
2002-03-28T00:00:00Z