Further insight into mechanism of action of clodronate: inhibition of mitochondrial ADP/ATP translocase by a nonhydrolyzable, adenine-containing metabolite.
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Once-yearly zoledronic acid in hip fracture preventionInnovative Target Therapies Are Able to Block the Inflammation Associated with Dysfunction of the Cholesterol Biosynthesis PathwaySLC transporters as therapeutic targets: emerging opportunitiesBisphosphonates: from bench to bedsideDrug screening on Hutchinson Gilford progeria pluripotent stem cells reveals aminopyrimidines as new modulators of farnesylation.Microglial depletion using intrahippocampal injection of liposome-encapsulated clodronate in prolonged hypothermic cardiac arrest in rats.Clodronate exerts an anabolic effect on articular chondrocytes mediated through the purinergic receptor pathway.Direct antitumour activity of zoledronic acid: preclinical and clinical data.Anti-Tumor Activity and Immunotherapeutic Potential of a Bisphosphonate Prodrug.Mechanisms of action of bisphosphonates: similarities and differences and their potential influence on clinical efficacy.Predictors of atypical femoral fractures during long term bisphosphonate therapy: a case series & review of literatureThe kd/kd mouse is a model of collapsing glomerulopathyThe alveolar macrophages in asthma: a double-edged sword.Bisphosphonates pathway.Discoveries, drugs and skeletal disorders.Differences between the bisphosphonates for the prevention and treatment of osteoporosis.The Chemical and Physical Properties of Poly(ε-caprolactone) Scaffolds Functionalised with Poly(vinyl phosphonic acid-co-acrylic acid).Bisphosphonamidate clodronate prodrug exhibits potent anticancer activity in non-small-cell lung cancer cellsModelling circulating tumour cells for personalised survival prediction in metastatic breast cancerBisphosphonates significantly increase the activity of doxorubicin or vincristine against canine malignant histiocytosis cells.Discovery, clinical development, and therapeutic uses of bisphosphonates.Modulating P2X7 Receptor Signaling during Rheumatoid Arthritis: New Therapeutic Approaches for BisphosphonatesEfficacy and Safety of Zoledronic Acid and Pamidronate Disodium in the Treatment of Malignant Skeletal Metastasis: A Meta-AnalysisSystemic macrophage depletion inhibits Helicobacter bilis-induced proinflammatory cytokine-mediated typhlocolitis and impairs bacterial colonization dynamics in a BALB/c Rag2-/- mouse model of inflammatory bowel disease.Bisphosphonates as potential adjuvants for patients with cancers of the digestive system.Mitochondrial permeability transition pore as a selective target for anti-cancer therapyEffect of long-term oral bisphosphonates on implant wound healing: literature review and a case report.Depletion of resident alveolar macrophages does not prevent Fas-mediated lung injury in mice.Immunomodulating role of bisphosphonates on human gamma delta T cells: an intriguing and promising aspect of their antitumour activity.Potential applications of biphosphonates in dental surgical implants.Evaluation of the predisposing factors and involved outcome of surgical treatment in bisphosphonate-related osteonecrosis of the jaw cases including bone biopsies.Zoledronic acid inhibits macrophage/microglia-assisted breast cancer cell invasionPharmacokinetic profile of bisphosphonates in the treatment of metabolic bone disorders.Clodronate acts on human osteoclastic cell proliferation, differentiation and function in a bioreversible manner.Bisphosphonamidate clodronate prodrug exhibits selective cytotoxic activity against melanoma cell lines.Toll-like receptor 9 expression is associated with breast cancer sensitivity to the growth inhibitory effects of bisphosphonates in vitro and in vivo.Bisphosphonates and atypical subtrochanteric fractures of the femur.Anticancer effect of bisphosphonates: new insights from clinical trials and preclinical evidence.Targeting the mitochondrial permeability transition: cardiac ischemia-reperfusion versus carcinogenesis.Physiology of the aging bone and mechanisms of action of bisphosphonates.
P2860
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P2860
Further insight into mechanism of action of clodronate: inhibition of mitochondrial ADP/ATP translocase by a nonhydrolyzable, adenine-containing metabolite.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年学术文章
@wuu
2002年学术文章
@zh
2002年学术文章
@zh-cn
2002年学术文章
@zh-hans
2002年学术文章
@zh-my
2002年学术文章
@zh-sg
2002年學術文章
@yue
2002年學術文章
@zh-hant
name
Further insight into mechanism ...... adenine-containing metabolite.
@en
Further insight into mechanism ...... adenine-containing metabolite.
@nl
type
label
Further insight into mechanism ...... adenine-containing metabolite.
@en
Further insight into mechanism ...... adenine-containing metabolite.
@nl
prefLabel
Further insight into mechanism ...... adenine-containing metabolite.
@en
Further insight into mechanism ...... adenine-containing metabolite.
@nl
P2093
P356
P1476
Further insight into mechanism ...... adenine-containing metabolite
@en
P2093
Alex Azhayev
H Kalervo Väänänen
Ilmo E Hassinen
Juha P Näpänkangas
Jukka Mönkkönen
Kari V Ylitalo
Maarit Kellinsalmi
P304
P356
10.1124/MOL.61.5.1255
P577
2002-05-01T00:00:00Z