about
Gene therapy for cardiovascular disease: advances in vector development, targeting, and delivery for clinical translationProspects for gene transfer for clinical heart failureGene therapy targets in heart failure: the path to translationFunctional role of phosphodiesterase 3 in cardiomyocyte apoptosis: implication in heart failureRandomized Clinical Trials of Gene Transfer for Heart Failure with Reduced Ejection Fraction.Cardiac-Directed Expression of Adenylyl Cyclase Catalytic Domain Reverses Cardiac Dysfunction Caused by Sustained Beta-Adrenergic Receptor Stimulation.Fibroblast-specific expression of AC6 enhances beta-adrenergic and prostacyclin signaling and blunts bleomycin-induced pulmonary fibrosis.Effects of cardiac overexpression of type 6 adenylyl cyclase affects on the response to chronic pressure overload.ROCK1 plays an essential role in the transition from cardiac hypertrophy to failure in mice.Disruption of adenylyl cyclase type V does not rescue the phenotype of cardiac-specific overexpression of Galphaq protein-induced cardiomyopathyBeneficial effects of adenylyl cyclase type 6 (AC6) expression persist using a catalytically inactive AC6 mutant.Adenylyl cyclase 6 deletion reduces left ventricular hypertrophy, dilation, dysfunction, and fibrosis in pressure-overloaded female mice.Adenylyl cyclase 6 improves calcium uptake and left ventricular function in aged heartsActivation of cardiac adenylyl cyclase expression increases function of the failing ischemic heart in mice.Preserved cardiac function despite marked impairment of cAMP generation.Heart failure -- a challenge to our current concepts of excitation-contraction coupling.Effect of overexpressed adenylyl cyclase VI on beta 1- and beta 2-adrenoceptor responses in adult rat ventricular myocytesTherapeutic efficacy of cardiosphere-derived cells in a transgenic mouse model of non-ischaemic dilated cardiomyopathy.Inhibition of adenylyl cyclase type 5 increases longevity and healthful aging through oxidative stress protectionActivated expression of cardiac adenylyl cyclase 6 reduces dilation and dysfunction of the pressure-overloaded heart.Anti-beta(1)-adrenergic receptor antibodies and heart failure: causation, not just correlationDisruption of type 5 adenylyl cyclase gene preserves cardiac function against pressure overload.New signaling pathways associated with increased cardiac adenylyl cyclase 6 expression: implications for possible congestive heart failure therapy.Adenylyl cyclase gene transfer in heart failure.Gene transfer for congestive heart failure: update 2013.Common genetic variants of the β2-adrenergic receptor affect its translational efficiency and are associated with human longevityModulation of beta-adrenergic receptor signaling in heart failure and longevity: targeting adenylyl cyclase type 5.Gene therapy in heart failure.Adenylyl cyclase subtype-specific compartmentalization: differential regulation of L-type Ca2+ current in ventricular myocytesIntravenous adeno-associated virus serotype 8 encoding urocortin-2 provides sustained augmentation of left ventricular function in mice.Physiological roles for G protein-regulated adenylyl cyclase isoforms: insights from knockout and overexpression studies.Gene therapy to treat cardiovascular disease.cAMP signal transduction in the heart: understanding spatial control for the development of novel therapeutic strategies.Adenylyl cyclase 6 deletion increases mortality during sustained β-adrenergic receptor stimulation.Unanticipated signaling events associated with cardiac adenylyl cyclase gene transfer.Adenylyl cyclase type VI gene transfer reduces phospholamban expression in cardiac myocytes via activating transcription factor 3.Intracoronary Gene Transfer of Adenylyl Cyclase 6 in Patients With Heart Failure: A Randomized Clinical TrialThe role of Epac in the heart.International Union of Basic and Clinical Pharmacology. CI. Structures and Small Molecule Modulators of Mammalian Adenylyl Cyclases.Activation of PH-domain leucine-rich protein phosphatase 2 (PHLPP2) by agonist stimulation in cardiac myocytes expressing adenylyl cyclase type 6.
P2860
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P2860
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年学术文章
@wuu
2002年学术文章
@zh-cn
2002年学术文章
@zh-hans
2002年学术文章
@zh-my
2002年学术文章
@zh-sg
2002年學術文章
@yue
2002年學術文章
@zh
2002年學術文章
@zh-hant
name
Adenylyl cyclase increases survival in cardiomyopathy.
@en
Adenylyl cyclase increases survival in cardiomyopathy.
@nl
type
label
Adenylyl cyclase increases survival in cardiomyopathy.
@en
Adenylyl cyclase increases survival in cardiomyopathy.
@nl
prefLabel
Adenylyl cyclase increases survival in cardiomyopathy.
@en
Adenylyl cyclase increases survival in cardiomyopathy.
@nl
P2093
P1433
P1476
Adenylyl cyclase increases survival in cardiomyopathy.
@en
P2093
Aziz Ander
David M Roth
H Kirk Hammond
Hamed Bayat
James S Swaney
Jeffrey D Drumm
Mei Hua Gao
P304
P356
10.1161/01.CIR.0000014968.54967.D3
P407
P577
2002-04-01T00:00:00Z