Structure-activity relationship studies of nordihydroguaiaretic acid inhibitors toward soybean, 12-human, and 15-human lipoxygenase.
about
Structure based design and synthesis of peptide inhibitor of human LOX-12: in vitro and in vivo analysis of a novel therapeutic agent for breast cancerDiscovery of a novel dual fungal CYP51/human 5-lipoxygenase inhibitor: implications for anti-fungal therapyA high throughput screen identifies potent and selective inhibitors to human epithelial 15-lipoxygenase-2Novel lipoxygenase inhibitors as neuroprotective reagents.Potent and selective inhibitors of human reticulocyte 12/15-lipoxygenase as anti-stroke therapiesDiscovery of potent and selective inhibitors of human reticulocyte 15-lipoxygenase-1.Discovery of potent and selective inhibitors of human platelet-type 12- lipoxygenase.Using enzyme assays to evaluate the structure and bioactivity of sponge-derived meroterpenesMinireview: 12-Lipoxygenase and Islet β-Cell Dysfunction in Diabetes.The potential of 12/15-lipoxygenase inhibitors in stroke therapy.Production of eicosanoids and other oxylipins by pathogenic eukaryotic microbes.A high-throughput mass spectrometric assay for discovery of human lipoxygenase inhibitors and allosteric effectors.Structure-activity relationship studies of flavonoids as potent inhibitors of human platelet 12-hLO, reticulocyte 15-hLO-1, and prostate epithelial 15-hLO-2.Inhibition of IGF-1R and lipoxygenase by nordihydroguaiaretic acid (NDGA) analogs.Lipids and immunoinflammatory pathways of beta cell destruction.Pseudoperoxidase investigations of hydroperoxides and inhibitors with human lipoxygenasesRedox-active antioxidant modulation of lipid signaling in vascular endothelial cells: vitamin C induces activation of phospholipase D through phospholipase A2, lipoxygenase, and cyclooxygenase.Synthesis, characterization, and anti-melanoma activity of tetra-O-substituted analogs of nordihydroguaiaretic acid.Synthesis and structure-activity relationship studies of 4-((2-hydroxy-3-methoxybenzyl)amino)benzenesulfonamide derivatives as potent and selective inhibitors of 12-lipoxygenaseThe role of laccase in prostaglandin production by Cryptococcus neoformans.15-Lipoxygenase inhibitors: a patent review.A novel inhibitor of 9-cis-epoxycarotenoid dioxygenase in abscisic acid biosynthesis in higher plants.Pyridine and pyrimidine analogs of acetaminophen as inhibitors of lipid peroxidation and cyclooxygenase and lipoxygenase catalysis.The arachidonic acid 5-lipoxygenase inhibitor nordihydroguaiaretic acid inhibits tumor necrosis factor alpha activation of microglia and extends survival of G93A-SOD1 transgenic mice.Clicked cinnamic/caffeic esters and amides as radical scavengers and 5-lipoxygenase inhibitors.Inflammation, Cancer and Oxidative Lipoxygenase Activity are Intimately Linked.Eicosanoid signaling and vascular dysfunction: methylmercury-induced phospholipase D activation in vascular endothelial cells.TGSA-Flex: Extending the capabilities of the Topo-Geometrical Superposition Algorithm to handle flexible molecules.Derivatives form better lipoxygenase inhibitors than piperine: in vitro and in silico study.Computer modeling in predicting the bioactivity of human 5-lipoxygenase inhibitors.Fucophlorethol C, a phlorotannin as a lipoxygenase inhibitor.Cross-reaction between proteins of Larrea divaricata Cav. (jarilla) and proteins of Gram-negative bacteria.Comparison of eight 15-lipoxygenase (LO) inhibitors on the biosynthesis of 15-LO metabolites by human neutrophils and eosinophils
P2860
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P2860
Structure-activity relationship studies of nordihydroguaiaretic acid inhibitors toward soybean, 12-human, and 15-human lipoxygenase.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年学术文章
@wuu
2002年学术文章
@zh
2002年学术文章
@zh-cn
2002年学术文章
@zh-hans
2002年学术文章
@zh-my
2002年学术文章
@zh-sg
2002年學術文章
@yue
2002年學術文章
@zh-hant
name
Structure-activity relationshi ...... an, and 15-human lipoxygenase.
@en
Structure-activity relationshi ...... an, and 15-human lipoxygenase.
@nl
type
label
Structure-activity relationshi ...... an, and 15-human lipoxygenase.
@en
Structure-activity relationshi ...... an, and 15-human lipoxygenase.
@nl
prefLabel
Structure-activity relationshi ...... an, and 15-human lipoxygenase.
@en
Structure-activity relationshi ...... an, and 15-human lipoxygenase.
@nl
P2093
P356
P1476
Structure-activity relationshi ...... an, and 15-human lipoxygenase.
@en
P2093
Barbara N Timmermann
Mikail Gezginci
Stephanie Whitman
Theodore R Holman
P304
P356
10.1021/JM0201262
P407
P577
2002-06-01T00:00:00Z