A common P-glycoprotein polymorphism is associated with nortriptyline-induced postural hypotension in patients treated for major depression.
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From pharmacogenetics to pharmacogenomics: the way toward the personalization of antidepressant treatmentP-glycoprotein inhibition increases the brain distribution and antidepressant-like activity of escitalopram in rodentsDrug resistance in brain diseases and the role of drug efflux transporters.Expression and function of multidrug resistance transporters at the blood-brain barriers.Pharmacogenetics of antidepressant response.Pharmacogenomics of MDR1/ABCB1 gene: the influence on risk and clinical outcome of haematological malignancies.Applying genome-wide gene-based expression quantitative trait locus mapping to study population ancestry and pharmacogeneticsCYP2C19 and ABCB1 gene polymorphisms are differently distributed according to ethnicity in the Brazilian general population.Pharmacogenetics of antidepressantsPharmacogenomics of antidepressant treatment effectsInteractions between antidepressants and P-glycoprotein at the blood-brain barrier: clinical significance of in vitro and in vivo findings.Neuropsychiatric pharmacogenetics: moving toward a comprehensive understanding of predicting risks and response.MDR1 haplotypes derived from exons 21 and 26 do not affect the steady-state pharmacokinetics of tacrolimus in renal transplant patients.Therapeutic drug monitoring of non-tricyclic antidepressant drugs.Influence of ABCB1 (P-glycoprotein) haplotypes on nortriptyline pharmacokinetics and nortriptyline-induced postural hypotension in healthy volunteers.Mechanisms of resistance to anticancer drugs: the role of the polymorphic ABC transporters ABCB1 and ABCG2.Genetic polymorphisms of ATP-binding cassette transporters ABCB1 and ABCG2: therapeutic implications.The Influence of C3435T Polymorphism of the ABCB1 Gene on Genetic Susceptibility to Depression and Treatment Response in Polish Population - Preliminary Report.Single nucleotide polymorphisms in human P-glycoprotein: its impact on drug delivery and disposition.Contribution of allelic variations in transporters to the phenotype of drug response.Active transport across the human placenta: impact on drug efficacy and toxicity.ABCB1 genotype and PGP expression, function and therapeutic drug response: a critical review and recommendations for future research.Genetic polymorphisms of drug transporters: pharmacokinetic and pharmacodynamic consequences in pharmacotherapy.Membrane transporter proteins: a challenge for CNS drug development.Computational analysis and predictive modeling of polymorph descriptors.A review on the relation between the brain-serum concentration ratio of drugs and the influence of P-glycoprotein.Transporter-mediated uptake into cellular compartments.Effect of the C3435T polymorphism of the multidrug resistance 1 gene on the severity of inflammatory bowel disease in Iranian Azeri Turks.Mechanisms of antidepressant resistancePharmacogenetics of antidepressant response: an updateThe permeability P-glycoprotein: a focus on enantioselectivity and brain distribution.Regioselective biotransformation of CNS drugs and its clinical impact on adverse drug reactions.Psychotropic drug-drug interactions involving P-glycoprotein.Drug access to the central nervous system in Alzheimer's disease: preclinical and clinical insights.Reliability of In Vitro and In Vivo Methods for Predicting the Effect of P-Glycoprotein on the Delivery of Antidepressants to the Brain.ABCB1 haplotypes but not individual SNPs predict for optimal response/failure in Egyptian patients with chronic-phase chronic myeloid leukemia receiving imatinib mesylate.Pharmacogenetics and Imaging-Pharmacogenetics of Antidepressant Response: Towards Translational Strategies.ABCB1 gene variants and antidepressant treatment outcome: A meta-analysis.Influence of ABCB1 polymorphisms and serum concentrations on venlafaxine response in patients with major depressive disorder.ABCB1 genotyping in the treatment of depression.
P2860
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P2860
A common P-glycoprotein polymorphism is associated with nortriptyline-induced postural hypotension in patients treated for major depression.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年学术文章
@wuu
2002年学术文章
@zh
2002年学术文章
@zh-cn
2002年学术文章
@zh-hans
2002年学术文章
@zh-my
2002年学术文章
@zh-sg
2002年學術文章
@yue
2002年學術文章
@zh-hant
name
A common P-glycoprotein polymo ...... treated for major depression.
@en
A common P-glycoprotein polymo ...... treated for major depression.
@nl
type
label
A common P-glycoprotein polymo ...... treated for major depression.
@en
A common P-glycoprotein polymo ...... treated for major depression.
@nl
prefLabel
A common P-glycoprotein polymo ...... treated for major depression.
@en
A common P-glycoprotein polymo ...... treated for major depression.
@nl
P2093
P2860
P356
P1476
A common P-glycoprotein polymo ...... treated for major depression.
@en
P2093
P2860
P2888
P304
P356
10.1038/SJ.TPJ.6500099
P577
2002-01-01T00:00:00Z