Matrix geometry determines optimal cancer cell migration strategy and modulates response to interventions.
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The Regulation of Cellular Responses to Mechanical Cues by Rho GTPasesRho, ROCK and actomyosin contractility in metastasis as drug targetsCapturing relevant extracellular matrices for investigating cell migrationEpithelia migration: a spatiotemporal interplay between contraction and adhesionPhysical view on migration modesRemodelling the extracellular matrix in development and diseaseThe multiple faces of leukocyte interstitial migrationThe role and regulation of blebs in cell migrationInvadopodia in contextSteering cell migration by alternating blebs and actin-rich protrusions.Apolar and polar transitions drive the conversion between amoeboid and mesenchymal shapes in melanoma cells.α5β1 integrin recycling promotes Arp2/3-independent cancer cell invasion via the formin FHOD3.Fibronectin Modulates Cell Adhesion and Signaling to Promote Single Cell Migration of Highly Invasive Oral Squamous Cell CarcinomaPerinuclear Arp2/3-driven actin polymerization enables nuclear deformation to facilitate cell migration through complex environments.Design of a microfluidic device to quantify dynamic intra-nuclear deformation during cell migration through confining environments.Coordination of contractility, adhesion and flow in migrating Physarum amoebae.Quantifying Modes of 3D Cell MigrationMembrane shrinkage and cortex remodelling are predicted to work in harmony to retract blebsLinearized texture of three-dimensional extracellular matrix is mandatory for bladder cancer cell invasion.Erk regulation of actin capping and bundling by Eps8 promotes cortex tension and leader bleb-based migration.Bleb-driven chemotaxis of Dictyostelium cells.A molecular switch for the orientation of epithelial cell polarizationComparative mechanisms of cancer cell migration through 3D matrix and physiological microtracksOpen source software for quantification of cell migration, protrusions, and fluorescence intensities.Cost-benefit analysis of the mechanisms that enable migrating cells to sustain motility upon changes in matrix environments.Computer-assisted quantification of motile and invasive capabilities of cancer cells.Estimating the 3D pore size distribution of biopolymer networks from directionally biased data.Long-term High-Resolution Intravital Microscopy in the Lung with a Vacuum Stabilized Imaging Window.Probing cell traction forces in confined microenvironments.RhoD Inhibits RhoC-ROCK-Dependent Cell Contraction via PAK6.Cadherin 6 promotes neural crest cell detachment via F-actin regulation and influences active Rho distribution during epithelial-to-mesenchymal transition.Diverse matrix metalloproteinase functions regulate cancer amoeboid migrationDendritic cells control fibroblastic reticular network tension and lymph node expansion.Topography design concept of a tissue engineering scaffold for controlling cell function and fate through actin cytoskeletal modulation3D collagen alignment limits protrusions to enhance breast cancer cell persistence.Bioengineering paradigms for cell migration in confined microenvironments.A novel 2.5D culture platform to investigate the role of stiffness gradients on adhesion-independent cell migration.Mechanotransduction: use the force(s).Regulation of microtubule dynamics by DIAPH3 influences amoeboid tumor cell mechanics and sensitivity to taxanesCell Blebbing in Confined Microfluidic Environments.
P2860
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P2860
Matrix geometry determines optimal cancer cell migration strategy and modulates response to interventions.
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年学术文章
@wuu
2013年学术文章
@zh
2013年学术文章
@zh-cn
2013年学术文章
@zh-hans
2013年学术文章
@zh-my
2013年学术文章
@zh-sg
2013年學術文章
@yue
2013年學術文章
@zh-hant
name
Matrix geometry determines opt ...... tes response to interventions.
@en
Matrix geometry determines opt ...... tes response to interventions.
@nl
type
label
Matrix geometry determines opt ...... tes response to interventions.
@en
Matrix geometry determines opt ...... tes response to interventions.
@nl
prefLabel
Matrix geometry determines opt ...... tes response to interventions.
@en
Matrix geometry determines opt ...... tes response to interventions.
@nl
P2093
P2860
P356
P1433
P1476
Matrix geometry determines opt ...... tes response to interventions.
@en
P2093
Alexander L Tournier
Melda Tozluoğlu
Robert P Jenkins
Steven Hooper
P2860
P2888
P304
P356
10.1038/NCB2775
P577
2013-06-23T00:00:00Z