DNA adducts from a tumorigenic metabolite of benzo[a]pyrene block human RNA polymerase II elongation in a sequence- and stereochemistry-dependent manner.
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Comparison of toxicogenomics and traditional approaches to inform mode of action and points of departure in human health risk assessment of benzo[a]pyrene in drinking waterRotational dynamics of DNA on the nucleosome surface markedly impact accessibility to a DNA repair enzyme.Malondialdehyde adducts in DNA arrest transcription by T7 RNA polymerase and mammalian RNA polymerase II.Stereochemistry and position-dependent effects of carcinogens on TATA/TBP binding.Formation and repair of tobacco carcinogen-derived bulky DNA adductsStructure of DNA polymerase beta with a benzo[c]phenanthrene diol epoxide-adducted template exhibits mutagenic featuresDevelopment of human cell biosensor system for genotoxicity detection based on DNA damage-induced gene expression.Nucleotide Excision Repair and Transcription-coupled DNA Repair Abrogate the Impact of DNA Damage on Transcription.DNA polymerase β gap-filling translesion DNA synthesisThe role of polycyclic aromatic hydrocarbon-DNA adducts in inducing mutations in mouse skinTranscription of DNA containing the 5-guanidino-4-nitroimidazole lesion by human RNA polymerase II and bacteriophage T7 RNA polymerase.Transcription elongation past O6-methylguanine by human RNA polymerase II and bacteriophage T7 RNA polymeraseLesion processing: high-fidelity versus lesion-bypass DNA polymerasesSynergistic damage by UVA radiation and pollutants.Molecular basis of transcriptional fidelity and DNA lesion-induced transcriptional mutagenesis.RNA polymerase II transcriptional fidelity control and its functional interplay with DNA modifications.The Nonbulky DNA Lesions Spiroiminodihydantoin and 5-Guanidinohydantoin Significantly Block Human RNA Polymerase II Elongation in Vitro.The attenuation of early benzo(a)pyrene-induced carcinogenic insults by diallyl disulfide (DADS) in MCF-10A cells.Polycyclic aromatic hydrocarbons within airborne particulate matter (PM(2.5)) produced DNA bulky stable adducts in a human lung cell coculture model.Human RNA polymerase II is partially blocked by DNA adducts derived from tumorigenic benzo[c]phenanthrene diol epoxides: relating biological consequences to conformational preferences.ATM activation accompanies histone H2AX phosphorylation in A549 cells upon exposure to tobacco smoke.Transcription processing at 1,N2-ethenoguanine by human RNA polymerase II and bacteriophage T7 RNA polymeraseDual roles of glycosyl torsion angle conformation and stereochemical configuration in butadiene oxide-derived N1 beta-hydroxyalkyl deoxyinosine adducts: a structural perspective.Transcription arrest at a lesion in the transcribed DNA strand in vitro is not affected by a nearby lesion in the opposite strand.Multiple states of stalled T7 RNA polymerase at DNA lesions generated by platinum anticancer agents.Behavior of T7 RNA polymerase and mammalian RNA polymerase II at site-specific cisplatin adducts in the template DNA.Genetic instability associated with loop or stem-loop structures within transcription units can be independent of nucleotide excision repair.
P2860
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P2860
DNA adducts from a tumorigenic metabolite of benzo[a]pyrene block human RNA polymerase II elongation in a sequence- and stereochemistry-dependent manner.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年学术文章
@wuu
2002年学术文章
@zh-cn
2002年学术文章
@zh-hans
2002年学术文章
@zh-my
2002年学术文章
@zh-sg
2002年學術文章
@yue
2002年學術文章
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2002年學術文章
@zh-hant
name
DNA adducts from a tumorigenic ...... reochemistry-dependent manner.
@en
DNA adducts from a tumorigenic ...... reochemistry-dependent manner.
@nl
type
label
DNA adducts from a tumorigenic ...... reochemistry-dependent manner.
@en
DNA adducts from a tumorigenic ...... reochemistry-dependent manner.
@nl
prefLabel
DNA adducts from a tumorigenic ...... reochemistry-dependent manner.
@en
DNA adducts from a tumorigenic ...... reochemistry-dependent manner.
@nl
P2093
P1476
DNA adducts from a tumorigenic ...... reochemistry-dependent manner.
@en
P2093
Alexander Kolbanovskii
Brian E Hingerty
David A Scicchitano
Nicholas E Geacintov
Rebecca A Perlow
Suse Broyde
P356
10.1016/S0022-2836(02)00593-4
P407
P577
2002-08-01T00:00:00Z