A small molecular weight catalytic metalloporphyrin antioxidant with superoxide dismutase (SOD) mimetic properties protects lungs from radiation-induced injury.
about
Comparative genomics of two Leptospira interrogans serovars reveals novel insights into physiology and pathogenesisSOD therapeutics: latest insights into their structure-activity relationships and impact on the cellular redox-based signaling pathwaysPartial volume rat lung irradiation: temporal fluctuations of in-field and out-of-field DNA damage and inflammatory cytokines following irradiationAEOL 10150 Mitigates Radiation-Induced Lung Injury in the Nonhuman Primate: Morbidity and Mortality are Administration Schedule-Dependent.Antioxidants reduce consequences of radiation exposure.Mesenchymal Stem Cell Therapy Protects Lungs from Radiation-Induced Endothelial Cell Loss by Restoring Superoxide Dismutase 1 ExpressionThe green tea extract epigallocatechin-3-gallate inhibits irradiation-induced pulmonary fibrosis in adult rats.Superoxide dismutase mimics: chemistry, pharmacology, and therapeutic potentialProteomic analysis of radiation-induced changes in rat lung: Modulation by the superoxide dismutase mimetic MnTE-2-PyP(5+).Alpha-2-macroglobulin as a radioprotective agent: a reviewDesign of Mn porphyrins for treating oxidative stress injuries and their redox-based regulation of cellular transcriptional activities.Targeted modulation of reactive oxygen species in the vascular endotheliumGenistein can mitigate the effect of radiation on rat lung tissue.Effect of lipophilicity of Mn (III) ortho N-alkylpyridyl- and diortho N, N'-diethylimidazolylporphyrins in two in-vitro models of oxygen and glucose deprivation-induced neuronal death.Radioprotection of the brain white matter by Mn(III) n-Butoxyethylpyridylporphyrin-based superoxide dismutase mimic MnTnBuOE-2-PyP5+.Novel synthetic SOD/catalase mimetics can mitigate capillary endothelial cell apoptosis caused by ionizing radiation.Targeting the TGF-beta1 pathway to prevent normal tissue injury after cancer therapy.Long-term administration of a small molecular weight catalytic metalloporphyrin antioxidant, AEOL 10150, protects lungs from radiation-induced injury.Modulation expression of tumor necrosis factor α in the radiation-induced lung injury by glycyrrhizic acidMn porphyrin-based superoxide dismutase (SOD) mimic, MnIIITE-2-PyP5+, targets mouse heart mitochondriaEndothelial targeting of antibody-decorated polymeric filomicelles.Strategies to decrease ongoing oxidant burden in chronic obstructive pulmonary disease.Oxidative stress in pulmonary fibrosis: a possible role for redox modulatory therapy.Dose Optimization Study of AEOL 10150 as a Mitigator of Radiation-Induced Lung Injury in CBA/J Mice.The metalloporphyrin antioxidant, MnTE-2-PyP, inhibits Th2 cell immune responses in an asthma modelThe antioxidant, MnTE-2-PyP, prevents side-effects incurred by prostate cancer irradiation.Extracellular superoxide dismutase in pulmonary fibrosisRadiation-induced lung injury is mitigated by blockade of gastrin-releasing peptide.Exploring the role of HIF-1 in early angiogenesis and response to radiotherapy.Short-term treatment with a SOD/catalase mimetic, EUK-207, mitigates pneumonitis and fibrosis after single-dose total-body or whole-thoracic irradiationSubcutaneous administration of bovine superoxide dismutase protects lungs from radiation-induced lung injury.Comparison of two Mn porphyrin-based mimics of superoxide dismutase in pulmonary radioprotectionSOD-like activity of Mn(II) beta-octabromo-meso-tetrakis(N-methylpyridinium-3-yl)porphyrin equals that of the enzyme itselfPharmacokinetics of the potent redox-modulating manganese porphyrin, MnTE-2-PyP(5+), in plasma and major organs of B6C3F1 miceEarly and late administration of MnTE-2-PyP5+ in mitigation and treatment of radiation-induced lung damageAntioxidants as potential therapeutics for lung fibrosis.Catalase and glutathione peroxidase mimics.Genome features of Leptospira interrogans serovar Copenhageni.Quercetin liposomes protect against radiation-induced pulmonary injury in a murine model.The antioxidant mimetic, MnTE-2-PyP, reduces intracellular growth of Mycobacterium abscessus.
P2860
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P2860
A small molecular weight catalytic metalloporphyrin antioxidant with superoxide dismutase (SOD) mimetic properties protects lungs from radiation-induced injury.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年学术文章
@wuu
2002年学术文章
@zh-cn
2002年学术文章
@zh-hans
2002年学术文章
@zh-my
2002年学术文章
@zh-sg
2002年學術文章
@yue
2002年學術文章
@zh
2002年學術文章
@zh-hant
name
A small molecular weight catal ...... from radiation-induced injury.
@en
A small molecular weight catalytic metalloporphyrin antioxidant with superoxide dismutase
@nl
type
label
A small molecular weight catal ...... from radiation-induced injury.
@en
A small molecular weight catalytic metalloporphyrin antioxidant with superoxide dismutase
@nl
prefLabel
A small molecular weight catal ...... from radiation-induced injury.
@en
A small molecular weight catalytic metalloporphyrin antioxidant with superoxide dismutase
@nl
P2093
P1476
A small molecular weight catal ...... from radiation-induced injury
@en
P2093
Ines Batinic-Haberle
Irwin Fridovich
Ivan Spasojevic
Mark W Dewhirst
Qin-fu Feng
Song K Kang
Thaddeus V Samulski
Zahid N Rabbani
Zeljko Vujaskovic
P304
P356
10.1016/S0891-5849(02)00980-2
P577
2002-09-01T00:00:00Z