Overexpression of a calpastatin transgene in mdx muscle reduces dystrophic pathology.
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Hypernitrosylated ryanodine receptor calcium release channels are leaky in dystrophic muscleMultiple molecular interactions implicate the connectin/titin N2A region as a modulating scaffold for p94/calpain 3 activity in skeletal musclePharmacological manipulation of cell death: clinical applications in sight?Ca2+-dependent regulations and signaling in skeletal muscle: from electro-mechanical coupling to adaptationRescue of dystrophic skeletal muscle by PGC-1α involves a fast to slow fiber type shift in the mdx mouseThe atypical calpains: evolutionary analyses and roles in Caenorhabditis elegans cellular degenerationGenetic evidence in the mouse solidifies the calcium hypothesis of myofiber death in muscular dystrophyMice lacking Homer 1 exhibit a skeletal myopathy characterized by abnormal transient receptor potential channel activityDeficiency in APOBEC2 leads to a shift in muscle fiber type, diminished body mass, and myopathy.Pharmacologic management of Duchenne muscular dystrophy: target identification and preclinical trialsComprehensive survey of p94/calpain 3 substrates by comparative proteomics--possible regulation of protein synthesis by p94.Bowman-Birk inhibitor attenuates dystrophic pathology in mdx mice.Muscle-specific calpastatin overexpression prevents diaphragm weakness in cecal ligation puncture-induced sepsis.A proteasome inhibitor fails to attenuate dystrophic pathology in mdx mice.Orai1 mediates exacerbated Ca(2+) entry in dystrophic skeletal muscleMitigation of muscular dystrophy in mice by SERCA overexpression in skeletal muscle.The role of proteases in excitation-contraction coupling failure in muscular dystrophy.Transgenic overexpression of dystroglycan does not inhibit muscular dystrophy in mdx miceTransgenic expression of {alpha}7{beta}1 integrin maintains muscle integrity, increases regenerative capacity, promotes hypertrophy, and reduces cardiomyopathy in dystrophic mice.L-arginine supplementation protects exercise performance and structural integrity of muscle fibers after a single bout of eccentric exercise in rats.Calpain chronicle--an enzyme family under multidisciplinary characterizationRegulation of the calpain and ubiquitin-proteasome systems in a canine model of muscular dystrophy.Chronic administration of a leupeptin-derived calpain inhibitor fails to ameliorate severe muscle pathology in a canine model of duchenne muscular dystrophyDuchenne muscular dystrophy and dystrophin: pathogenesis and opportunities for treatmentOverexpression of the cytotoxic T cell (CT) carbohydrate inhibits muscular dystrophy in the dyW mouse model of congenital muscular dystrophy 1A.Porcine models of muscular dystrophyCalpain activation impairs neuromuscular transmission in a mouse model of the slow-channel myasthenic syndromecAMP signaling in skeletal muscle adaptation: hypertrophy, metabolism, and regenerationAnalysis of calpain-3 protein in muscle biopsies of different muscular dystrophies from India.Mechanisms of stretch-induced muscle damage in normal and dystrophic muscle: role of ionic changes.Stressed out: the skeletal muscle ryanodine receptor as a target of stressAbsence of Dystrophin Disrupts Skeletal Muscle Signaling: Roles of Ca2+, Reactive Oxygen Species, and Nitric Oxide in the Development of Muscular Dystrophy.Calpastatin inhibits motor neuron death and increases survival of hSOD1(G93A) mice.An association between the calpastatin (CAST) gene and keratoconusWasting mechanisms in muscular dystrophy.Leupeptin-based inhibitors do not improve the mdx phenotype.Gene therapy in large animal models of muscular dystrophy.Calcium influx is sufficient to induce muscular dystrophy through a TRPC-dependent mechanism.Impact of genetic insights into calpain biology.Cell-matrix interactions in muscle disease.
P2860
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P2860
Overexpression of a calpastatin transgene in mdx muscle reduces dystrophic pathology.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年学术文章
@wuu
2002年学术文章
@zh
2002年学术文章
@zh-cn
2002年学术文章
@zh-hans
2002年学术文章
@zh-my
2002年学术文章
@zh-sg
2002年學術文章
@yue
2002年學術文章
@zh-hant
name
Overexpression of a calpastatin transgene in mdx muscle reduces dystrophic pathology.
@en
Overexpression of a calpastatin transgene in mdx muscle reduces dystrophic pathology.
@nl
type
label
Overexpression of a calpastatin transgene in mdx muscle reduces dystrophic pathology.
@en
Overexpression of a calpastatin transgene in mdx muscle reduces dystrophic pathology.
@nl
prefLabel
Overexpression of a calpastatin transgene in mdx muscle reduces dystrophic pathology.
@en
Overexpression of a calpastatin transgene in mdx muscle reduces dystrophic pathology.
@nl
P356
P1476
Overexpression of a calpastatin transgene in mdx muscle reduces dystrophic pathology.
@en
P2093
Melissa J Spencer
Ronald L Mellgren
P304
P356
10.1093/HMG/11.21.2645
P577
2002-10-01T00:00:00Z